TSC Alliance: Research Grants

The TSC Alliance is committed to advancing the understanding of tuberous sclerosis complex (TSC) through research grants aimed at early-career researchers. In 2024, they plan to award three to four grants focused on key areas such as phenotypic heterogeneity, TSC signaling pathways, disease models, and clinical biomarkers. These grants will support independent researchers in furthering innovative studies to benefit those affected by TSC.

The TSC Alliance is dedicated to creating a future where everyone affected by tuberous sclerosis complex (TSC) can live their fullest lives. We invest in early-career researchers to drive innovative TSC research and to foster a diverse group of researchers dedicated to our shared mission. In 2024, we anticipate awarding three or four awards to postdoctoral fellows and early-stage investigators depending on merit, requested budgets, and funds available.
Research grant proposals should address one of the following four high-priority areas:Understanding phenotypic heterogeneity in TSC, i.e., research on genetic, biologic, or environmental factors that might explain why TSC is so different from person to personGaining a deeper knowledge of TSC signaling pathways and the cellular consequences of TSC deficiencyImproving TSC disease models, whether cell-based, tissue-based, or animal modelsDeveloping clinical biomarkers or patient-reported outcome measures for TSC, particularly those that assess disease burden or stratify an individual’s risk of progression or developing specific manifestations of TSCResearch grant awards are intended to provide funding for an independent researcher, whether tenure-track faculty, non-tenure-track faculty or staff, or an equivalent level at a research institution or company. The award may support laboratory supplies, personnel costs, services, or equipment necessary to conduct the proposed research.The TSC Alliance fully supports collaborative projects between co-investigators, but only one investigator may be considered the “Principal Investigator” for the purpose of applying through the online system.