The LAM Foundation: Pilot and Feasibility Research Awards Grant

The LAM Foundation: Pilot and Feasibility Research Awards Grant

Status: ACTIVE
Funder: The Lam Foundation
Amount: Up to US $50,000
Last Updated: November 02, 2025

Summary

The LAM Foundation offers Pilot and Feasibility Research Awards aimed at fostering innovative research in lymphangioleiomyomatosis (LAM). These awards support hypothesis-driven studies with the potential to advance understanding and treatment options for this rare disease. Applicants can request a maximum of $50,000 for a period of up to one year. The Foundation prioritizes new researchers, encouraging fresh perspectives in LAM research to enhance patient care and ultimately achieve a future without LAM.

Overview

NOTE: The first step in the process of a grant application to The LAM Foundation is to submit a Letter of Intent (LOI). The submission of an LOI is required for each grant category. Applicants must create a profile and be logged in to ProposalCentral to access The LAM Foundation’s LOI Form.If your LOI is approved, The LAM Foundation will invite you to submit a full grant application. Mission The LAM Foundation urgently seeks new treatments and a cure for LAM. Vision A future without LAM. Lymphangioleiomyomatosis (LAM) is a rare and progressive lung disease that primarily affects women and has no known cure. Founded in 1995 as a grassroots effort, The LAM Foundation is the global leader in the fight against LAM. It has evolved into an organization that is described by the National Heart, Lung, and Blood Institute (NHLBI) as “a model for voluntary health agencies.” The LAM Foundation provides support and education for women with LAM and their families, engages doctors and scientists to continue to learn more about the disease, and raises funds for continued research. In May 2015, the FDA approved Rapamune as the first effective treatment for LAM, based on research and patient engagement supported by The LAM Foundation. In over 30 years, The LAM Foundation has raised nearly $37 million, with more than $19 million directed to research. Thanks to those grants, investigators were able to obtain an estimated $90 million in subsequent funding from other sources to advance the field of LAM research. This research effort has produced significant grant-related publications, a diagnostic biomarker that can obviate the need for lung biopsy, and a pivotal clinical trial that has identified the first treatment. As we look ahead to the next 30 years, we are focused on investing in scientific research that will allow an earlier diagnosis and the identification and FDA approval of new therapies for treatment. We will be working with our clinician partners to improve access to comprehensive patient care and support while creating fund development strategies to ensure the sustainability of our work. We will be moving forward to attain our vision – a future without LAM. Pilot and Feasibility Grant The objective of this type of award is to provide funds to encourage the development and testing of new hypotheses and/or new methods in research areas relevant to LAM. The proposed work must be hypothesis generating or hypothesis testing, reflecting innovative approaches to important questions in LAM research or development of novel methods, and providing sufficient preliminary data to justify the Foundation’s support. Results from Pilot and Feasibility Grants should have the potential to lead to the submission of applications for funding from other agencies (e.g., NIH). The award is not intended to support the continuation of programs initiated under other granting mechanisms. An applicant may be an MD, DO, PhD, DVM or equivalent postdoctoral researcher, postgraduate medical trainee, junior faculty or established investigator. The LAM Foundation encourages applications from investigators new to LAM research who could contribute their knowledge and expertise. Funding Funding Level: A maximum of $50,000 may be requested. Period: Up to 1 year of support is available.

Eligibility

You can learn more about this opportunity by visiting the funder's website. The LAM Foundation collaborates with scientists, academic institutions, and non-profit organizations to enable access to data, biospecimens, and researchers to facilitate LAM research.Only one LOI may be submitted by the same research laboratory or research group.

Ineligibility

The award is not intended to support the continuation of programs begun under other granting mechanisms.