PCRF: Translational Research Grant

PCRF: Translational Research Grant

Status: ACTIVE
Funder: Pediatric Cancer Research Foundation
Amount: Up to US $100,000
Last Updated: January 16, 2026

Summary

The Pediatric Cancer Research Foundation (PCRF) is dedicated to funding innovative research aimed at curing childhood cancer. With a focus on collaborative efforts, PCRF has contributed over $51 million since 1982, significantly improving survival rates for childhood cancers. The Translational Research Grant supports cutting-edge clinical trials and therapeutic approaches, enhancing the journey from laboratory discoveries to patient care. This initiative underscores the urgent need for effective treatments, offering hope for children diagnosed with cancer and their families.

Overview

NOTE: A Letter of Intent is required in order to be invited to submit a grant application. About PCRF The Pediatric Cancer Research Foundation identifies and invests in leading-edge research that demonstrates the best hope for curing childhood cancer. PCRF invites you to walk with us as we vigorously pursue eliminating childhood cancer through research. An average of 43 children and adolescents are diagnosed with cancer every day in the United States (almost 16,000 annually) and that number is dramatically compounded when we look worldwide: nearly 250,000 new cases of cancer affect children annually, or 700 new children affected every day around the globe (The Lancet Oncology. 2013; 14(3): e95-e103). As evidenced by these numbers, pediatric cancer is not rare – in fact, it remains the number one disease killer of all children. More children die from cancer than pediatric AIDS, asthma, diabetes, cystic fibrosis, and congenital anomalies combined (Cancer in Children and Adolescents). Time will not stand still as we search for a cure, which means we must work quickly, strategically, diligently, and in collaboration to combat childhood cancer. We thank you for your partnership and contributions that help give hope to children and families. Founded in 1982 by physicians, parents, and community leaders, Pediatric Cancer Research Foundation (PCRF) has raised over $51 Million for cancer research since its inception. This represents the ongoing hard work of physicians, researchers, volunteers, staff, and community partners dedicated to our future generation’s health—our children. Over the last 40 years, we have seen drastic improvements – overall survival rates for childhood cancer have risen from 10% to almost 85%. Because of research, the cancer death rate has dropped more dramatically for children than for any other age group. However, there are still childhood cancers that have not had the same results – rare and aggressive cancers continue to devastate families and rob children of their childhoods. Together, we’ve made considerable strides in the treatment, care, and prevention of childhood cancers. However, as we look back and celebrate our progress, we also look forward – knowing there is more work to be done. PCRF is a pioneer in eliminating childhood cancer through our ability to identify and fund cutting-edge research. We exclusively target funds toward emerging and breakthrough opportunities. Your partnership with PCRF powers hopeful advancements: Hope for a cure, hope for aggressive treatments that attack cancer cells but leave the healthy cells, hope for long-term quality of life through safer therapies to fight cancer. Hope for new research, new protocols, new interventions. Background At PCRF, we are unique in our approach to funding childhood cancer research — working directly with doctors, researchers, and nurses to identify the specific challenges they face in bringing new treatments to and caring for children with cancer. Our careful distribution of grants has allowed doctors and nurses to speed up the process of bringing the latest and most promising life-saving treatments to seriously ill children. The result is bringing hope to childhood cancer patients now and in the future. Translational Research Grant This grant is given to single or multi-institutional programs that involve open, cancer clinical trials or consortia, and implement new approaches to therapy. These grants support “bench to bedside” research, whose endpoint is often the planning or initiation of a clinical trial.

Eligibility

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