Funding Amount

Up to US $100,000

Deadline

Deadline not published

Grant Type

Foundation

Overview

The Pediatric Cancer Research Foundation (PCRF) is dedicated to funding innovative research aimed at curing childhood cancer. With a focus on collaborative efforts, PCRF has contributed over $51 million since 1982, significantly improving survival rates for childhood cancers. The Translational Research Grant supports cutting-edge clinical trials and therapeutic approaches, enhancing the journey from laboratory discoveries to patient care. This initiative underscores the urgent need for effective treatments, offering hope for children diagnosed with cancer and their families.

NOTE: A Letter of Intent is required in order to be invited to submit a grant application.
About PCRF
The Pediatric Cancer Research Foundation identifies and invests in leading-edge research that demonstrates the best hope for curing childhood cancer. PCRF invites you to walk with us as we vigorously pursue eliminating childhood cancer through research.
As evidenced by these numbers, pediatric cancer is not rare – in fact, it remains the number one disease killer of all children. More children die from cancer than pediatric AIDS, asthma, diabetes, cystic fibrosis, and congenital anomalies combined (Cancer in Children and Adolescents).
Founded in 1982 by physicians, parents, and community leaders, Pediatric Cancer Research Foundation (PCRF) has raised over $51 Million for cancer research since its inception. Because of research, the cancer death rate has dropped more dramatically for children than for any other age group. However, there are still childhood cancers that have not had the same results – rare and aggressive cancers continue to devastate families and rob children of their childhoods.
Together, we’ve made considerable strides in the treatment, care, and prevention of childhood cancers. PCRF is a pioneer in eliminating childhood cancer through our ability to identify and fund cutting-edge research. We exclusively target funds toward emerging and breakthrough opportunities.
Your partnership with PCRF powers hopeful advancements: Hope for a cure, hope for aggressive treatments that attack cancer cells but leave the healthy cells, hope for long-term quality of life through safer therapies to fight cancer. Hope for new research, new protocols, new interventions.
Background
At PCRF, we are unique in our approach to funding childhood cancer research — working directly with doctors, researchers, and nurses to identify the specific challenges they face in bringing new treatments to and caring for children with cancer. Our careful distribution of grants has allowed doctors and nurses to speed up the process of bringing the latest and most promising life-saving treatments to seriously ill children. The result is bringing hope to childhood cancer patients now and in the future.
This grant is given to single or multi-institutional programs that involve open, cancer clinical trials or consortia, and implement new approaches to therapy. These grants support “bench to bedside” research, whose endpoint is often the planning or initiation of a clinical trial.

What Pediatric Cancer Research Foundation actually gave

Source: IRS Form 990, 2025

Grants in 2025
15
Total given
$1.55M
Median grant
$45K
Range
$8,000–$550K
  • By dollars: New York 46%, California 22%, North Carolina 13%. Top recipient cities: Los Angeles, CA; Cary, NC; New York, NY.
  • 0% of grants with a stated purpose were for general or operating support.
  • 43% of recipients were new grantees, not repeat recipients.

Example grants

  • V Foundation · Cary, NC

    Cancer research

    $204K

  • Memorial Sloan Kettering · New York, NY

    Towards curative epigenetic therapies of refractory pediatric sarcomas

    $150K

  • City of Hope · Duarte, CA

    Single-cell dissecting of high-risk b-cell acute lymphoblastic leukemia

    $100K

  • Dana Farber · Boston, MA

    Advancing liquid biopsies to the clinic for patients with ewing sarcoma

    $100K

  • Stanford · Palo Alto, CA

    Targeting mitochondrial pathways in pediatric aml

    $100K

IRS Form 990, 2025. Amounts as reported by the funder. Full 990 history →

Focus Areas & Funding Uses

Fields of Work

  • Cancer
  • Science research

Categories

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