Parkinson's Disease Therapeutics Pipeline Grant Program

The Parkinson's Disease Therapeutics Pipeline Grant Program, funded by the Michael J. Fox Foundation, invites pre-proposals for therapeutic development aimed at addressing unmet needs in Parkinson's disease (PD). This initiative supports projects that seek to prevent or delay disease progression while enhancing symptom management. Selected pre-proposals can transition to full proposals with guidance from MJFF, fostering innovative approaches to improve the lives of those affected by PD.

NOTE:
Applicants may submit a pre-proposal application at any time. Pre-proposals will be reviewed by MJFF within three weeks of submission. This stage is your first and best opportunity to determine if MJFF is the right partner for you.Applicants whose pre-proposal is selected for further consideration will be invited to submit a full proposal through one of the five review cycles (see full proposal due dates to the right). MJFF staff will work with applicants to define the most flexible and fastest option for review. Invited applicants will have the opportunity to consult with MJFF on proposal development. Funding decisions will be communicated within three months of full proposal submission.
Background
Parkinson’s disease (PD) affects nearly 1 million people in the US and over 6 million worldwide, with expected increases over the coming decades. PD is highly heterogeneous: individuals experience a wide array of motor and non-motor symptoms, many of which depend on disease severity and duration. Though understanding of PD and its causes is growing, many questions remain. There are no drugs available that alter the progression of Parkinson’s disease, and current symptomatic treatments provide limited relief but come with complications and side effects.
The Michael J. Fox Foundation for Parkinson’s Research (MJFF) is dedicated to finding a cure for Parkinson's disease (PD) through an aggressively funded research agenda and to ensuring the development of improved therapies for those living with Parkinson's today. Strategic MJFF funding fosters a robust pipeline of treatments for improved symptoms management as well as those that may modify disease course. Beyond funding, additional resources such as research tools, open access data sets and connection to MJFF's broad network of scientists, clinicians and the patient community offer added opportunities to enable a program’s success.
Objective
This program seeks to advance therapeutic development through pre-clinical and/or clinical testing of approaches addressing unmet needs of people with Parkinson’s disease (PD). The program is set up to benefit therapeutics with clear potential to prevent, stop, or delay disease progression or to reduce the burden of daily symptoms.