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Drug Screening Program

CHORDOMA FOUNDATION

Foundation Rolling (Quarterly) Grants for Science ResearchGrants for Cancer Nonprofits
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Funding Amount

Varies

Deadline

Rolling / Open

Grant Type

foundation

Overview

Chordoma Foundation Drug Screening Program

Overview: The Drug Screening Program enables researchers and pharmaceutical companies to test promising drugs in chordoma cell and mouse models at a fraction of the time and cost of conducting such studies independently. The program generates preclinical data packages necessary to initiate new clinical trials.

Focus:

  • Screening drug candidates in chordoma cell and mouse models

  • Testing single agents and drug combinations

  • Generating efficacy and safety data

  • Supporting the transition from preclinical research to clinical trials

    • Eligibility:

  • Academic researchers

  • Pharmaceutical and biotechnology companies

  • Collaborations between institutions and industry

    • How It Works:

  • Researchers/companies submit drugs for screening

  • Foundation tests in chordoma models

  • Results help generate rationale for clinical trials

  • Data shared with research partners

    • Recent Collaborations (as of 2022):

  • Sphaera Pharma - testing PI3K/mTOR pathway inhibitor

  • Kronos Bio - testing CDK9 inhibitor

  • Institute of Cancer Research

  • Broad Institute of MIT and Harvard

    • Advantages:

  • Reduced time and cost compared to independent testing

  • Access to chordoma-specific expertise and models

  • Accelerates development of new treatments

    • Research Outcomes: Results published at major conferences (AACR) and used to inform clinical trial design

    How to Apply

    How to Access the Drug Screening Program

    1. Contact the Foundation: Interested researchers or companies should contact the Chordoma Foundation to inquire about screening opportunities

    2. Submission Process:
    - Present drug candidate(s) and rationale for testing
    - Define testing parameters and endpoints
    - Agree on timeline and data sharing arrangements

    3. Program Capabilities:
    - Cell-based screening models
    - Mouse model testing
    - Single agent and combination studies
    - Dose-response and efficacy evaluation

    4. Deliverables:
    - Preclinical data packages
    - Results suitable for publication and regulatory submissions
    - Scientific support for clinical trial design

    Note: Specific application forms and detailed protocols should be obtained directly from the Foundation.

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    Focus Areas & Funding Uses

    Fields of Work

    science-researchcancer

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