Crazy 8 Initiative Grant Program on Pediatric Brain Tumors

Crazy 8 Initiative Grant Program on Pediatric Brain Tumors

Status: ACTIVE
Funder: Alex’s Lemonade Stand Foundation for Childhood Cancer
Amount: US $3,000,000 - US $5,000,000
Last Updated: November 09, 2025

Summary

The Crazy 8 Initiative Grant Program, established by Alex’s Lemonade Stand Foundation, aims to advance pediatric brain tumor treatments through collaborative research efforts. This program encourages partnerships between multiple institutions and emphasizes the inclusion of patient advocates. With a budget range of $3-5 million over four years, the initiative seeks innovative proposals that focus on improving outcomes for children and adolescents affected by these tumors, contributing significantly to the fight against childhood cancer.

Overview

About Alex’s Lemonade Stand Foundation (ALSF) Alex's Lemonade Stand Foundation (ALSF) emerged from the front yard lemonade stand of 4-year-old Alexandra “Alex” Scott, who was fighting cancer and wanted to raise money to find cures for all children with cancer. Her spirit and determination inspired others to support her cause, and when she passed away at the age of 8, she had raised $1 million. Since then, the Foundation bearing her name has evolved into a national fundraising movement. Today, ALSF is one of the leading funders of pediatric cancer research in the U.S. and Canada, funding more than 1,500 research projects and providing programs to families affected by childhood cancer. ALSF is also the only childhood cancer research organization that has been given the NCI peer-reviewed funder designation for rigorous selection of research grants. The mission of ALSF is to change the lives of children with cancer through funding impactful research, raising awareness, supporting families, and empowering everyone to help cure childhood cancer. Crazy 8 Initiative Grant Program on Pediatric Brain Tumors Program Description This ALSF Crazy 8 RFA focuses on developing and enhancing pediatric brain tumor treatments. The focus must be on pediatric/adolescent brain tumors and should be a consortium of two or more institutions with different areas of research collaborating to integrate their expertise. It is strongly encouraged to have a patient advocate on the team. Budget Depending on the type of project and the size of the team, the requested budget should be in the range of $3-5 million USD over four years.

Eligibility

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