Funding Amount

Up to US $125,000

Deadline

Rolling / Open

Grant Type

foundation

Can we apply?

Check your organization against each line. Taken from the listing; confirm with the funder's guidelines.

Other requirements

  • website.

Overview

2026 Innovation Grant

Status: ACTIVE
Funder: Alex’s Lemonade Stand Foundation for Childhood Cancer
Amount: Up to US $125,000
Last Updated: August 25, 2025

Summary

The 2026 Innovation Grant by Alex’s Lemonade Stand Foundation aims to foster groundbreaking research in pediatric oncology. This grant provides crucial seed funding of up to $250,000 over two years to established researchers proposing innovative ideas that have the potential to significantly impact childhood cancer treatment. The program emphasizes clinical translation and encourages novel approaches that diverge from previous research directions, ensuring a focus on impactful solutions for children battling cancer.

Overview

About Alex’s Lemonade Stand Foundation (ALSF) Alex's Lemonade Stand Foundation (ALSF) emerged from the front yard lemonade stand of 4-year-old Alexandra “Alex” Scott, who was fighting cancer and wanted to raise money to find cures for all children with cancer. Her spirit and determination inspired others to support her cause, and when she passed away at the age of 8, she had raised $1 million. Since then, the Foundation bearing her name has evolved into a national fundraising movement. Today, ALSF is one of the leading funders of pediatric cancer research in the U.S. and Canada, funding more than 1,500 research projects and providing programs to families affected by childhood cancer. ALSF is also the only childhood cancer research organization that has been given the NCI peer-reviewed funder designation for rigorous selection of research grants. The mission of ALSF is to change the lives of children with cancer through funding impactful research, raising awareness, supporting families, and empowering everyone to help cure childhood cancer. 2026 Innovation Grant Program Description ALSF is committed to creating opportunities for new and innovative research into treatments and cures for childhood cancers. The Innovation Grant is designed to provide critical and significant seed funding for established researchers with a novel approach to pediatric oncology scientific investigation. Proposals should have clinical translation in view. This may represent a change in research direction and/or an innovative new idea that moves away from an investigator’s prior research but for which a strong case is made for the potential impact on childhood cancers. Budget The requested budget should be in proportion to the scope of the proposed project and should be for direct costs of $250,000 USD or below over two years. A maximum of $125,000 in total direct costs may be requested per year.

Eligibility

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What Alexs Lemonade Stand Foundation actually gave

Source: IRS Form 990, 2025

Grants in 2025
58
Total given
$19.14M
Median grant
$162K
Range
$6,000–$2.32M
  • By dollars: California 19%, Massachusetts 16%, Pennsylvania 15%. Top recipient cities: Boston, MA; New York, NY; Philadelphia, PA.
  • 0% of grants with a stated purpose were for general or operating support.
  • 40% of recipients were new grantees, not repeat recipients.

Example grants

  • Children's Hospital of Philadelphia · Philadelphia, PA

    Pediatric cancer research

    $2.32M

  • Dana-Farber Cancer Institute · Boston, MA

    Pediatric cancer research

    $2.25M

  • University of California San Francisco · San Francisco, CA

    Pediatric cancer research

    $1.93M

  • St Jude Children's Research Hospital · Memphis, TN

    Pediatric cancer research

    $1.47M

  • Baylor College of Medicine · Houston, TX

    Pediatric cancer research

    $1.42M

IRS Form 990, 2025. Amounts as reported by the funder. Full 990 history →

Focus Areas & Funding Uses

Fields of Work

cancerscience-research

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