Brain Cancer Research Investigator Grant

Application Procedure

1. Submission Method: Email all proposals in PDF form to research@bcured.org
2. Deadline: Applications must be received on or before April 1 (next deadline: April 1, 2027, pending program resumption)
3. Review Process: Medical Advisory Board reviews and evaluates applications; Grants Committee conducts subsequent review; B*CURED Board of Directors makes final approval
4. Notification: All applicants notified via email of decision
5. Confidentiality: All applications confidential and available only to Board of Directors, Grants Committee, and Medical Advisory Board

Required Application Materials

• Cover Letter – Explain career goals and how B*CURED grant assists overall research program; include specific paragraph on institutional environment suitability
• Project Title
• Non-Technical Project Description – 250 words or less
• Technical Project Description – 250 words or less
• NIH Bio-sketch of applicant
• Letters of Support from project collaborators (include names, emails, phone contacts)
• Letter of Support from Department Head or Chief stating applicant has resources and time to perform research (include name, email, phone contact)
• Detailed Budget – NIH format; no indirect costs permitted; keep salary costs to 60% of budget
• List of Other Financial Support – All active and pending financial support pertaining to clinical work or research during funding term
• Financial Conflicts of Interest – List all equity, fiduciary responsibility, advisory payments, or sponsored research agreements with for-profit entities over last 2 years
• Scientific Proposal – 5 pages total, organized as follows:
- Project Abstract (½ page) – Brief clinical problem statement including background and significance; how approach is novel and feasible; statement of how findings will advance brain tumor therapeutic research - Specific Aims (½ page) – Specific scientific hypothesis with at least two specific aims - Preliminary Data (1 page) – Use one or two key figures to illustrate major points (preferably from peer-reviewed published literature) - Research Plan (2 pages) – For clinical proposals: define study population, state number of patients, number of sites; specific inclusion/exclusion criteria; clinical endpoints and measurement timing. For translational science proposals: explicitly state how study connects basic science finding to clinical or pre-clinical studies - Statistics (½ page) – Expected treatments (where applicable); sample size estimates (80% and 90% power) - Study Limitations (½ page) – Discuss limitations and potential pitfalls
• Bibliography
• Biohazards Statement
• Human Investigation Statement
• Laboratory Animal Statement (if applicable)

Special Requirements for Clinical Trial Proposals

• Applicants should consult: Friedman LM, Furberg CD, DeMets DL: Fundamentals of Clinical Trials – 3rd ed. New York, Springer-Verlag New York, Inc., 1998

Submission Notes

• Scan all letters of recommendation into electronic version of application
• All signatures must be electronic in PDF form
• Contact research@bcured.org with any questions