Aptadel Therapeutics Grant - ADEL-101 (Initial Award)
Funding Amount
$500,000
Deadline
Deadline not published
Grant Type
Foundation
Deadline history & next window
- Cycle
- One-time opportunity
- Tracked since
- April 2026
Source: the cycle recorded on this listing. Confirm dates with the funder.
Overview
Aptadel Therapeutics Initial Grant
Geographic Scope: Spain (Barcelona)
Focus Areas
- Drug: ADEL-101 (aptamer-based drug conjugate - ApDC)
- Target: EWS::FLI1 fusion - primary driver of Ewing sarcoma
- Mechanism: Two-pronged therapeutic with homing mechanism and toxic payload
- Homing: RNA-based aptamer recognizing epHA2 (overexpressed on Ewing sarcoma cells)
- Payload: siRNA designed to silence EWSR1::FLI1 (Type 1) fusion gene
Research Support
Funding supports key preclinical studies including:
- Testing different dosing strategies and combination regimens
- Evaluating in vivo efficacy of ADEL-101
- Generating data for Investigational New Drug (IND)-enabling discussions
- Bringing therapy closer to clinical trials
What Little Warrior Foundation Inc actually gave
Source: IRS Form 990, 2025
- Grants in 2025
- 8
- Total given
- $795K
- Median grant
- $66K
- Range
- $20K–$263K
- By dollars: Massachusetts 43%, New York 22%, Florida 13%. Top recipient cities: Boston, MA; Braintree, MA; New York, NY.
- 0% of grants with a stated purpose were for general or operating support.
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Boston Children's Hospital · Boston, MA
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Focus Areas & Funding Uses
Fields of Work
- Cancer
- Science research
Categories
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Based on past cycles
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