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Foundation Annual Grants for Science ResearchGrants for Cancer Nonprofits
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Funding Amount

Up to $500,000 for translational/correlative grants; Up to $800,000 for clinical trials

Deadline

November 15, 2026

221 days left

Grant Type

foundation

Overview

Annual Grants Program

Funder: The Osteosarcoma Institute (OSI)

Geographic Scope: National and international

Focus Areas:

  • Clinical trials of new potential therapies

  • Correlative science (evaluation of how and why potential new therapies work or don't work in clinical trials)

  • Basic biology of osteosarcoma cancer and its metastasis

  • Translational research (pre-clinical research bridging laboratory findings to clinical application)

  • High-risk/high-impact research (bold, pioneering ideas that challenge traditional approaches)

    • Award Amounts:

  • Translational/correlative grants: Up to $500,000

  • Clinical trials: Up to $800,000

  • High-risk/high-impact studies: Variable (e.g., $100,000)

    • Eligibility:

  • Researchers with osteosarcoma research proposals

  • Studies focused on developing better treatments and ultimately a cure for osteosarcoma

  • Both preclinical and clinical research welcome

    • Application Process:

  • Two-stage annual grant cycle

  • Letters of Intent (LOI) due mid-November each year

  • Full applications follow LOI acceptance

  • Expert review committee evaluates submissions

  • Awards announced in spring

    • What They Fund:

  • Research using new technologies

  • Projects with clear timeline to clinical testing

  • Immunotherapy approaches

  • CAR-T cell therapy developments

  • Studies on osteosarcoma metastasis prevention

  • Genomics and molecular biology research

    • What They Don't Fund:

  • Not explicitly stated

    • Background:

  • OSI launched in 2017 and has awarded over $5 million to osteosarcoma research since inception

  • Standard treatments for osteosarcoma have not changed in 40 years

  • OSI is a leading funder of osteosarcoma research

  • Strategic Advisory Board includes Nobel Prize recipient and experts across multiple disciplines

  • Starting in 2019, OSI awards grants in three main categories; added high-risk/high-impact category in 2023

    • Contact Information:

  • Address: 3963 Maple Avenue Suite 390, Dallas, TX 75219

  • Phone: 972.903.8408

  • Email: info@osinst.org

  • Website: osinst.org

    • How to Apply

    Application Process

    Two-Stage Annual Grant Cycle:

    1. Stage One: Letter of Intent (LOI)
    - LOI deadline: Mid-November each year
    - LOI submissions outline the proposed research

    2. Stage Two: Full Application
    - Invited after LOI acceptance
    - Full applications required for selected LOI submissions

    Expert Review:

  • Submissions evaluated by OSI's expert review committee

  • Committee provides feedback to applicants, even those not selected

  • Feedback includes specific advice and direction for improvement

    • Award Announcements:

  • Grants announced in spring (typically June)

    • Post-Award Requirements:

  • Principal Investigators must provide progress reports every six months

  • Reports shared with OSI Strategic Advisory Board

  • Results made available to the public upon completion

  • Emphasis on transparency and accountability

    • Additional Support:

  • OSI offers invaluable feedback, advice, and guidance to researchers

  • $20,000 spot/ad hoc grants available to help researchers elevate work for future resubmission

  • Researchers receive mentorship from Nobel Prize recipient and expert board members

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    Focus Areas & Funding Uses

    Fields of Work

    science-researchcancer

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