2026 Pilot Research Award - Targeting GBP-1 to Overcome Chemotherapy Resistance and Immune Suppression in Ovarian Cancer
Funding Amount
$25,000
Deadline
Deadline not published
Grant Type
Foundation
Deadline history & next window
- Cycle
- Annual
- Tracked since
- April 2026
Source: the cycle recorded on this listing. Confirm dates with the funder.
Can we apply?
Check your organization against each line. Taken from the listing; confirm with the funder's guidelines.
Other requirements
- Oregon (US)
Overview
Focus Area: Mechanistic and translational research on chemotherapy resistance and immune suppression
Project Description
This pilot award provides catalytic support for mechanistic and translational research examining the role of Guanylate-Binding Protein 1 (GBP-1) in ovarian cancer progression, chemotherapy resistance, and immune suppression. Using complementary murine models and human tumor analyses, this project seeks to define how GBP-1 shapes the tumor microenvironment and to evaluate a first-in-class GBP-1 inhibitor as a potential therapeutic strategy. The award provides key experiments that will strengthen the foundation for future external funding and novel combination therapies.
Investigators
- Dr. Sanjay Malhotra | OHSU Knight Cancer Institute
- Dr. Thomas Duhen | Providence Portland Cancer Institute
- Dr. Christopher Darus | Providence Portland Cancer Institute
Mission Alignment
The SHOC Foundation supports diverse portfolios of ovarian cancer research spanning early detection, novel therapeutics, survivorship, and equity. The foundation invests in innovative science, translational discovery, and supports the next generation of women investigators.
What Sherie Hildreth Ovarian Cancer Foundation actually gave
Source: IRS Form 990, 2023 — the most recent filing with itemized grants
- Grants in 2023
- 1
- Total given
- $75K
- Median grant
- $75K
- By dollars: Oregon 100%. Top recipient cities: Portland, OR.
Example grants
Ohsu Foundation 75000 · Portland, OR
Cancer research
$75K
Focus Areas & Funding Uses
Fields of Work
- Cancer
- Science research
Categories
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