The Otho Sa Sprague Memorial Institute logo

The Otho Sa Sprague Memorial Institute

CHICAGO, IL EIN: 36-6068723 Website

The Otho S.A. Sprague Memorial Institute, now operating as the Sprague Foundation, is an independent private foundation based in Chicago, Illinois. Founded in 1911, the organization has operated for over a century as a grantmaking institution dedicated to health-focused philanthropy in the Chicago region.

Financial Overview

From 2024 IRS Form 990-PF · View filing

Total Assets

Annual Giving

$2.1M

+16.2% YoY

Grant Count

19

-5.0% YoY

Avg Grant Size

$110K

+22.3% YoY

Research compiled by Grantable AI from public sources. Last updated April 2026.

Mission & Focus Areas

The foundation's mission is to investigate the root causes of illness and prevent and relieve human suffering. This mandate, established by founder Otho Sylvester Arnold Sprague, specifically directs the organization's work toward "the investigation of the cause of disease and the prevention and relief of human suffering in the City of Chicago, County of Cook, State of Illinois."

The foundation recognizes that social determinants of health—including intergenerational poverty, systemic racism, and geographic location—significantly impact quality of life and life expectancy. The organization's philanthropic work has historically supported transformational initiatives including the Chicago Asthma Consortium, Consortium to Lower Obesity in Chicago Children, and Chicago Health Atlas.

As of 2025, the foundation has narrowed its strategic focus to two key priority areas for the 2025-2028 period:

  • Community Health Access: Reducing barriers to health and creating new pathways for underserved populations and communities
  • Healthcare Workforce: Expanding professional pathways for underrepresented groups and supporting work environments that encourage staff performance, safety, retention, and satisfaction

Grantmaking

The foundation functions as an enabling organization, seeding efforts to help partner organizations leverage resources, establish proof of concept, and embed new innovations within health systems.

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Geographic Focus

Where this funder awards grants

The foundation's grantmaking is concentrated in Chicago and the Chicagoland region, with a specific mandate to serve the City of Chicago, County of Cook, and the State of Illinois.

Grant Distribution by State

4states

Cities

CHICAGOChicagoEVANSTONNew OrleansSPRINGFIELDUrbanaWASHINGTONWashington

Financial History

Multi-year comparison from IRS filings

As of December 2024:

  • Total Assets: $47,375,682
  • Total Revenues: $4,862,162
  • Total Expenses: $2,439,477
  • Investment Income and Dividends: $1,091,826
  • Net Gain from Sale of Non-Inventory Assets: $3,769,336
  • Staff: 1 employee

Organization Details:

  • EIN: 36-6068723
  • IRS Classification: 501(c)(3)
  • Tax-Exempt Status: Since September 1942
  • Incorporated: 1910 in Illinois
Revenue
Expenses
Qualifying Distributions
Net Investment Income
$0$0.275$0.55$0.8250000000000001$1.1201920202021202220232024
Metric202420232022
Total Assets
Revenue
Expenses
Qualifying Distributions
Net Investment Income
Distributable Amount

Giving Over Time

Total grant dollars and number of grants per year

$0$527K$1M$2M$2M17 grants201924 grants202014 grants202123 grants202220 grants202319 grants2024

Grant Insights

How this funder distributes its grants

Top Recipients

Top 10 recipients in 2024

UNIVERSITY OF IL AT CHIC…$417KSWEDISH COVENANT HOSPITA…$200KHEARTLAND ALLIANCE HEALTH$180KESPERANZA HEALTH CENTERS$138KCITY OF COLLEGES OF CHIC…$125KILLINOIS CHAPTER OF THE …$125KANN & ROBERT H LURIE CHI…$120KGREATER CHICAGO FOOD DEP…$100KLAWNDALE CHRISTIAN HEALT…$100KMOBILE CARE FOUNDATION$100K

Grant Size Distribution

100 grants across all recorded years

30<$50K27$50–100K37$100–250K5$250–500K1$500K–1M$1–5M$5M+

Giving History

Grant recipients and amounts by year

No grants recorded for .

Leadership & Key People

Leadership team and compensation from IRS filings

James N. Alexander serves as Executive Director of the organization.

Compensation Overview

From 2024 IRS filing

CHRISTY PRAHLEXECUTIVE DIRECTOR$158K

From 2024 filing

NameTitleHoursCompensation
CHRISTY PRAHLEXECUTIVE DIRECTOR40$157,574
JOHN A SVOBODAPRESIDENT AND DIRECTOR2
LEE FRANCIS MD MPHVICE PRESIDENT AND DIRECTOR2
DAVID G O'NEILLTREASURER AND DIRECTOR2
MICHELLE L COLLINSSECRETARY AND DIRECTOR2
EDWARD K CHANDLERDIRECTOR2
KARY MCILWAINDIRECTOR2
JULIAN G POSADADIRECTOR2
T SANDS THOMPSONDIRECTOR2
BRYAN S TRAUBERT MDDIRECTOR2
KEVIN B WEISS MD MPHDIRECTOR2
STEPHANIE A WHYTE MD MBADIRECTOR2
REBECCA M WURTZ MD MPHDIRECTOR2

Recent News & Activity

Recent developments and announcements

The foundation awarded a grant to the Institute of Medicine of Chicago for a Black and Latino Male Medical & Dental Student Mentoring program, demonstrating continued commitment to addressing health equity gaps through workforce development initiatives.

Otho S. A. Sprague Memorial Institute Awards Black and Latino Male Medical

The organization invested over $2 million annually in Chicago's health sector and has maintained more than 100 years of continuous philanthropic investment in the region's health infrastructure.

Illinois Children's Healthcare Foundation Announces New Health ...

Contact Information

  • Website: spraguechicago.org
  • Phone: 872-842-1543
  • Address: PO Box 806214, Chicago, IL 60680-4123

Related Funders

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Data last updated April 2026. Sourced from IRS Form 990-PF filings. Research dossier generated April 2026.

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