The Mary H Cain Foundation

Greater Houston Community Foundation

Houston, TX

The Foundation makes grants through donor-advised and other donor-established funds for public benefit, human services, education, and health, including initiatives addressing economic mobility and poverty in Harris County. In 2024, its median grant was $25,000; it serves Greater Houston, while grants also go to recipients elsewhere in Texas and beyond. It does not accept proposals for the upcoming High-Impact Grantmaking cycle and plans to invite selected organizations or collaboratives to apply.

Foundation for the Carolinas

Charlotte, NC

Foundation For The Carolinas funds nonprofits and other eligible organizations working in areas such as education, health and human services, the environment, youth development, and animal welfare, primarily across 13 counties in North and South Carolina. Its 2024 grants had a median of $25,000, though amounts varied widely; most grants are donor-recommended and have no application process, while some competitive programs accept applications under program-specific rules.

The Winston-Salem Foundation

Winston-Salem, NC

The Winston-Salem Foundation funds nonprofits and community groups serving Forsyth County, North Carolina, across areas including education, housing, health, arts, community development, and human services. Its 2024 grants had a median of $25,000; specific programs offer up to $2,000 for small grants, $30,000 for civic engagement and inclusion, and $15,000 through The Women’s Fund. It accepts applications through its grants portal for listed programs, subject to their requirements and deadlines.

Communities Foundation of Texas Inc

Dallas, TX

Communities Foundation of Texas funds charitable work in health, wealth, living, and learning, with much of its grantmaking supporting North Texas nonprofits; its 2025 grants had a median of $18,779, though award sizes varied widely. Nearly all opportunities are by invitation, and its Nonprofit Gateway profile is not a grant application.

BNSF Railway Foundation

Fort Worth, TX

The BNSF Railway Foundation supports civic, cultural, educational, health and human services, environmental, and youth programs, as well as general operating costs, in communities served by BNSF across its 28-state network. Its 2025 median grant was $2,500; its current grants program lists awards of $1,000–$10,000.

Baker Hughes Foundation

Houston, TX

Community Foundation of North Texas (Tax

Fort Worth, TX

The Community Foundation of North Texas supports nonprofits through grants for areas including animal welfare, conservation, community development, nonprofit capacity, and opportunity, primarily in North Texas, including seven listed counties. Its 2024 grants had a median amount of $14,250, with awards ranging from $5,100 to $1.5 million. It offers competitive grants through application cycles; nonprofits cannot apply for donor-advised grants.

Michael & Susan Dell Foundation

Austin, TX

The Michael & Susan Dell Foundation funds education, health, family economic stability, and nonprofit capacity, with a strong focus on children and families and its deepest investment in Texas, especially Greater Austin; it also supports work elsewhere in the U.S. and internationally. Its 2024 grants ranged from $75 to $50 million, with a median of $19,324. It accepts unsolicited requests through an online application.

American Heart Association Inc

Dallas, TX

The American Heart Association funds basic, clinical, behavioral, translational, population, and other research on cardiovascular, cerebrovascular, and brain health, mainly through research awards to eligible U.S.-based nonprofit institutions. In 2025, grants ranged from $5,000 to $9.9 million, with a median award of $20,000. Applications are submitted through designated programs; the profile does not state whether unsolicited requests are accepted.

Laura and John Arnold Foundation

Houston, TX

Arnold Ventures funds evidence-based research, evaluation, and policy work in criminal justice, health care, higher education and career pathways, public finance, and infrastructure. Its 2024 grants had a median of $122,776 (ranging from $685 to $12.5 million); based in Houston, Texas, it does not accept unsolicited requests, but accepts applications through specific requests for proposals.

The Dallas Foundation

Dallas, TX

The Dallas Foundation funds nonprofits and other charitable organizations working on early childhood, maternal and child health, economic mobility, homelessness, youth mental health, and community needs, primarily in Dallas County. Its 2024 itemized grants had a median of $25,000; listed 2026 cycles seek requests of $5,000–$50,000 or $15,000–$50,000, depending on the program. It accepts applications through grant cycles when open; none are currently open, and organizations outside Dallas County may be eligible if most people they serve live there.