Spastic Paraplegia Foundation Inc
The Spastic Paraplegia Foundation, Inc. is the only organization in the Americas dedicated to finding a cure for Hereditary Spastic Paraplegia (HSP) and Primary Lateral Sclerosis (PLS). Founded in 2002 as an all-volunteer, not-for-profit organization, SPF has raised and funded over $12 million in research grants with 97% of donations directed toward research. The foundation operates with low overhead and works with a Scientific Advisory Board of world-renowned neuroscience experts to review and fund the most promising research proposals aimed at discovering treatments and cures for these rare neurodegenerative disorders.
Spastic Paraplegia Foundation Inc at a glance
In short: Spastic Paraplegia Foundation Inc gave $964K across 5 grants in 2025 (avg $193K), mostly in Arizona. Source: 2025 IRS Form 990.
- Annual giving (2025)
- $963,957
- +211.0% vs 2024
- Grants made (2025)
- 5
- +66.7% vs 2024
- Average grant
- $192,791
- +86.6% vs 2024
- Median grant
- $149,957
- Total assets
- $3,551,338
- +14.9% vs 2024
- Primary geography
- Arizona (52% of itemized 2025 grant dollars)
- Latest 990 filing
- Form 990, 2025 View filing
Data from IRS Form 990, 2025; updated October 2026.
Who Spastic Paraplegia Foundation Inc funds
How this funder distributes its grants
Top Recipients
Top 5 recipients in 2025
The largest 2025 recipient was Critical Path Institute ($500K). Together the top 5 received $964K.
Grant Size Distribution
20 grants across all recorded years
The most common grant size was in the $100–250K range: 14 grants of 20 (70%).
Geographic Focus
Where this funder awards grants
Grant Distribution by State
Share of 2025 grant dollars across all 5 itemized grants.
Cities
How Spastic Paraplegia Foundation Inc gives
- Giving grew 222% from 2022 to 2025. Method
From the foundation's IRS Form 990 filings. Methodology.
Giving History
Giving Over Time
Total grant dollars and number of grants per year
From 2020 to 2025, annual grant giving ranged from $299K (2020) to $1.3M (2023). In 2025 it made 5 grants totaling $964K.
Grants by year
Grant recipients and amounts by year
| Recipient | Purpose | Amount |
|---|---|---|
| Critical Path Institute Tucson, AZ | Hereditary Spastic Paraplegia (HSP) and Primary Lateral Sclerosis (PLS) Taskforce to create a consortium between leading academic institutions, pharmaceutical industries, patient groups, non-governmental agencies and regulatory agencies to address unmet drug development needs for patients living with HSP and PLS. | $500,000 |
| Drexel University Philadelphia, PA | Combination Therapy for HSP-SPG4: Repurposed FDA Drug, BpV-Mediated Regeneration, and Activity-Based Rehabilitation | $150,000 |
| Columbia University New York, NY | Extension of Natural History Study of PLS | $149,957 |
| To Cure A Rose Foundation Austin, TX | Frank Davis Amenability and Tool Box | $89,000 |
| Children's Hospital Corporation Grants Management Harvard University Boston, MA | Bridge SP-CERN to fund the existing project until NIH funding was received | $75,000 |
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Financial History
Multi-year comparison from IRS filings
| Filing year | Total Assets | Revenue | Expenses | Grants paid | Grants | Net Investment Income |
|---|---|---|---|---|---|---|
| 2025 | $3,551,338 | $1,742,632 | $1,418,562 | $963,957 | 5 | $119,112 |
| 2024 | $3,089,987 | $1,730,780 | $899,593 | $310,000 | 3 | $90,207 |
| 2023 | $3,308,442 | $1,324,845 | $1,928,614 | $1,276,000 | 6 | $30,504 |
| 2022 | $2,855,492 | $1,249,081 | $748,401 | $299,755 | 2 | $-63,697 |
| 2021 | $2,650,188 | $1,153,340 | $715,727 | $561,000 | 4 | $29,866 |
| 2020 | $2,291,149 | $929,060 | $991,817 | $298,904 | 2 | $27,553 |
About Spastic Paraplegia Foundation Inc
Based on IRS filings
Spastic Paraplegia Foundation Inc is a public charity focused on Diseases, Disorders & Medical Disciplines, based in O Fallon, MO. IRS filing data is available from 2020 through 2025. As of 2025, the organization holds $3.6M in total assets. In 2025, it awarded 5 grants totaling $964K. Net investment income was $119K.
Focus Areas
Leadership & Key People
Officers and directors from IRS filings
Spastic Paraplegia Foundation Inc is led by Greg Pruitt, President & Director since 2023 (on filings since 2020); 2 of 13 officers listed in 2025 are compensated.
Officers on the 2025 filing
Greg Pruitt
President & Director
Director → President, 2021
President → President & Director, 2023
On filings since 2020
40 hrs/week
No compensation reported
Carina Thurgood
Director
On filings since 2020
2 hrs/week
No compensation reported
Dina Landphair
Director
On filings since 2020
5 hrs/week
No compensation reported
Frank Davis
Director
President → Director, 2021
On filings since 2020
2 hrs/week
No compensation reported
Jackie Wellman
Director
On filings since 2020
2 hrs/week
No compensation reported
Jim Sheorn
Vice President & Director
Director → Vice President & Director, 2023
On filings since 2020
30 hrs/week
No compensation reported
John Cobb
Director
On filings since 2020
2 hrs/week
No compensation reported
Tina Croghan
Director
On filings since 2020
5 hrs/week
No compensation reported
Hank Chiuppi
Secretary & Director
On filings since 2023
20 hrs/week
No compensation reported
Becki Cochran
Director
New on the 2025 filing
2 hrs/week
No compensation reported
Sara Kramer
Director
New on the 2025 filing
1 hr/week
No compensation reported
Lorri Steiner
Treasurer
On filings since 2024
6 hrs/week
$38K (2024) → $31K (2025)
Linda Arnold
Fundraising & Relationship Development Manager
New on the 2025 filing
35 hrs/week
$33K (2025)
Former officers (7)
- Former: Corey Braastad (2020–2024) — Director
- Former: David Lewis (2020–2024) — Treasurer
- Former: Henry Chiuppi (2020–2022) — Secretary
- Former: Linda Gentner (2020–2022) — Vice President
- Former: Mark Weber (2020–2022) — Director
- Former: Tina Coughan (2022) — Director
- Former: Jean Chambers (2020–2021) — Director
Data from IRS Form 990 filings, 2020–2025. "On filings since" is the earliest filing we hold that lists the person; hours are average hours per week as reported.
Compensation Overview
From 2025 IRS filing
The highest reported compensation on the 2025 filing was $33K, to Linda Arnold (Fundraising and Relationship Development Manager). 2 officers or directors reported compensation on that filing.
Frequently asked questions about Spastic Paraplegia Foundation Inc
How much does Spastic Paraplegia Foundation Inc give each year?
Spastic Paraplegia Foundation Inc gave $964K across 5 grants in 2025, according to its 2025 IRS Form 990. In 2024 it gave $310K across 3 grants.
What is Spastic Paraplegia Foundation Inc's typical grant size?
Spastic Paraplegia Foundation Inc's median grant in 2025 was $149,957, and its average grant was $192,791, across 5 grants on its 2025 IRS Form 990.
Where does Spastic Paraplegia Foundation Inc give grants?
Spastic Paraplegia Foundation Inc gives mostly in Arizona: 52% of the grant dollars itemized on its 2025 IRS Form 990 went to recipients there. The next largest states were Pennsylvania (16%) and New York (16%).
Does Spastic Paraplegia Foundation Inc give general operating support?
Not in 2025: none of the 5 grants with a stated purpose on Spastic Paraplegia Foundation Inc's 2025 IRS Form 990 were described as general or operating support.
Who are Spastic Paraplegia Foundation Inc's largest grantees?
Spastic Paraplegia Foundation Inc's largest 2025 grantees include Critical Path Institute ($500,000), Drexel University ($150,000) and Columbia University ($149,957), according to its 2025 IRS Form 990. Together they received 83% of its itemized 2025 grant dollars.
How large is Spastic Paraplegia Foundation Inc?
Spastic Paraplegia Foundation Inc reported $3.6M in total assets on its 2025 IRS Form 990. Its revenue that year was $1.7M.
What is Spastic Paraplegia Foundation Inc?
Spastic Paraplegia Foundation Inc is a public charity focused on Diseases, Disorders & Medical Disciplines, based in O Fallon, MO. It holds $3.6M in total assets as of 2025.
What is Spastic Paraplegia Foundation Inc's EIN?
Spastic Paraplegia Foundation Inc's EIN (Employer Identification Number) is 04-3594491. IRS Form 990 filing data is available on this page for 2020–2025.
Data last updated October 2026. Sourced from IRS Form 990 filings.
Data update history
(7)
When this profile's IRS filing data changed on Grantable
- Updated Form 990 for fiscal year 2023 (received by the IRS October 24, 2024)
- Updated Form 990 for fiscal year 2024 (received by the IRS May 13, 2025)
- Updated Form 990 for fiscal year 2020 (received by the IRS November 12, 2021)
- Updated Form 990 for fiscal year 2021 (received by the IRS November 15, 2022)
- Updated Form 990 for fiscal year 2022 (received by the IRS November 18, 2023)
- Added Form 990 for fiscal year 2025 (received by the IRS August 13, 2026)
- IRS filings on file for fiscal years 2020–2024
Live grants for the work Spastic Paraplegia Foundation Inc funds
Diseases, Disorders & Medical Disciplines Open opportunities, soonest deadline first.
Explore Open Grants
Browse active grant opportunities in Spastic Paraplegia Foundation Inc's focus areas in our free grants database
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