RTW Foundation

NEW YORK, NY EIN: 83-1433853

RTW Foundation is a private grantmaking foundation based in New York City that serves as the philanthropic arm of biotech investment firm RTW Investments. The foundation supports scientific research into rare diseases and funds community health initiatives focused on underserved populations.

Financial Overview

From 2024 IRS Form 990-PF · View filing

Total Assets

$72.3M

+2.5% YoY

Annual Giving

$2.7M

+55.3% YoY

Grant Count

30

-14.3% YoY

Avg Grant Size

$90K

+81.2% YoY

Research compiled by Grantable AI from public sources. Last updated April 2026.

Mission & Focus Areas

RTW Foundation's mission is to power community initiatives and scientific research to improve the health of underserved populations.

The foundation operates across two primary focus areas:

Research: Supporting scientific initiatives to aid in the development of medicines for neglected rare diseases. The foundation collaborates with research teams, families, and advocacy organizations globally to work toward treatments for rare conditions, recognizing that over 10,000 rare diseases exist yet fewer than 5% have effective treatments.

Community Engagement: Building partnerships with local organizations to advance health equity in New York City. The foundation is committed to supporting underserved communities through partnerships with community-based organizations responding to local health needs. The foundation also operates BioQuest, a STEM mentoring program designed for middle and high school students.

Grantmaking

Community grants support organizations providing free primary and specialized care, transportation support, care navigation, and appointment incentives to address healthcare access barriers in New York City.

Grant Range

is approximately $215

Average Grant

is approximately $215

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Geographic Focus

Where this funder awards grants

The foundation funds initiatives across the United States and internationally. Primary geographic focus includes major U.S. cities such as New York, Los Angeles, and Chicago, as well as international locations including London. The foundation has significantly increased its community funding focus in New York City.

Grant Distribution by State

18states
+10 more states

Cities

AirmontAlbert LeaAliso ViejoBethesdaBostonBronxBrooklynChapel HillChicagoColumbusDallasDamascusDurhamEnglewoodGrand RapidsJenkintownLawrencevilleLong Island CityLos AngelesMadison

Financial History

Multi-year comparison from IRS filings

Assets & Revenue:

  • Total assets: $72.3 million (as of 2024)
  • Total revenue: $547,684 (2024)
  • Total expenses: $4.5 million (2024)
  • Annual grants awarded: $1.7 million (2024)

Financial Trajectory: Assets have grown 2.6% from the previous year, indicating steady financial stability.

Revenue
Expenses
Qualifying Distributions
Net Investment Income
$0$27M$54M$81M$108M20202021202220232024
Metric202420232022
Total Assets$72,251,838$70,509,364$65,875,065
Revenue$547,684$241,708$24,113
Expenses$4,498,504$3,477,900$4,931,201
Qualifying Distributions$3,966,007$3,008,345$4,227,722
Net Investment Income$509,522$172,259
Distributable Amount$3,671,615$3,101,536$3,672,766

Giving Over Time

Total grant dollars and number of grants per year

$0$673K$1M$2M$3M4 grants202014 grants202147 grants202235 grants202330 grants2024

Grant Insights

How this funder distributes its grants

Top Recipients

Top 10 recipients in 2024

National Philanthropic D…$1.5MRare Village Foundation$151KBoston Childrens Hospita…$150KWashington University Sc…$150KUniversity of North Caro…$150KAIRnyc$50KArete Education$50KCommunity Health Action …$50KEast Harlem Health Outre…$50KExodus Transitional Comm…$50K

Grant Size Distribution

130 grants across all recorded years

66<$50K35$50–100K27$100–250K1$250–500K$500K–1M1$1–5M$5M+

Giving History

Grant recipients and amounts by year

No grants recorded for .

Leadership & Key People

Leadership team and compensation from IRS filings

  • Roderick Wong, MD – Chairman
  • Stephanie A. Sirota – President
  • Marti Speranza Wong – President of Community Engagement

All leadership positions are held on a voluntary basis without compensation.

Compensation Overview

From 2024 IRS filing

From 2024 filing

NameTitleHoursCompensation
Roderick Wong MDChairman2
Stephanie A SirotaPresident2
Marti Speranza WongPresident, Community Engagement2

Recent News & Activity

Recent developments and announcements

2026

In January 2026, RTW Foundation announced over $850,000 in grant funding for 11 nonprofit organizations dedicated to expanding health access for underserved communities across New York City. This represented an increase of over 80% in community funding compared to previous years, reflecting the foundation's response to rising healthcare access barriers in the city. The foundation cited federal policy shifts and high medical costs as key drivers of healthcare access challenges, particularly for Black and Hispanic adults and uninsured populations.

RTW Foundation Awards Over $850,000 to Strengthen Healthcare Access in NYC

Subject Areas

Focus areas based on grantmaking activity

Related Funders

Similar funders by location and focus area

Data last updated April 2026. Sourced from IRS Form 990-PF filings. Research dossier generated April 2026.

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