Oneblood Foundation Inc

Thomas A & Mary S James Foundation

St Petersburg, FL

The Thomas A & Mary S James Foundation funds arts and cultural institutions, education, health, and community and social services, with most grant dollars going to Florida organizations. In 2025, it made 90 grants ranging from $1,000 to $1 million, with a median grant of $5,000. It gives only to preselected organizations and does not accept unsolicited requests.

Central Florida Foundation

Orlando, FL

Central Florida Foundation supports nonprofit operations, social-impact initiatives, scholarships, and grassroots capacity-building across Central Florida, with focus areas including economic stability, healthcare, livability, education, and social connection. Its 2025 grants ranged from $5,000 to $331,743, with a median of $10,250; some application-based opportunities are available, while Community Investment Grants are by invitation only.

The Winston-Salem Foundation

Winston-Salem, NC

The Winston-Salem Foundation funds nonprofits and community groups serving Forsyth County, North Carolina, across areas including education, housing, health, arts, community development, and human services. Its 2024 grants had a median of $25,000; specific programs offer up to $2,000 for small grants, $30,000 for civic engagement and inclusion, and $15,000 through The Women’s Fund. It accepts applications through its grants portal for listed programs, subject to their requirements and deadlines.

Universal Orlando Foundation Inc

Orlando, FL

Universal Orlando Foundation supports education, children, families, basic needs, arts and culture, and services for children with life-threatening illnesses or disabilities, primarily in Central Florida. In 2024, grants ranged from $6,250 to $385,389, with a median of $40,500. Its online donation request program accepts eligible Florida nonprofits’ applications for theme park tickets; apply at least 60 days before the event.

American Campus Charities Foundation

Austin, TX

Wayne M Densch Charitable Trust

Orlando, FL

The trust funds programs assisting disadvantaged people, including services for people experiencing homelessness, children and families in crisis, education, and child-abuse prevention, primarily in Florida. Its 2025 grants ranged from $1,000 to $250,000, with a median of $13,000; it accepts requests not limited to preselected organizations, and submissions should include organizational and board profiles, financial statements, and program details.

Enterprise Holdings Foundation

Saint Louis, MO

Enterprise Holdings Foundation supports nonprofits in health, education, arts, disaster relief, reforestation, hunger relief, and community equity, with an emphasis on organizations actively supported by Enterprise employees and their families. Its reported grants range widely: 2024 giving averaged about $7,700 across 9,499 grants, while the foundation also offers awards of up to $40,000; it supports communities where Enterprise operates worldwide. Unsolicited requests are accepted at any time, but eligible applications must be submitted by an Enterprise team member or their spouse or domestic partner on behalf of a nonprofit they actively support.

Community Foundation of Tampa Bay Inc

Tampa, FL

The Community Foundation of Tampa Bay funds nonprofits addressing economic opportunity, environmental sustainability, health, education, and community vitality in Hillsborough, Pinellas, Pasco, Hernando, and Citrus counties. Its annual competitive grants are typically $10,000–$50,000; it also accepts year-round requests for urgent, unforeseen needs of up to $250,000. Apply through the relevant grant opportunity; the profile does not state whether general unsolicited requests are accepted.

The Community Foundation for Northeast Florida Inc

Jacksonville, FL

The Community Foundation for Northeast Florida supports nonprofits and civic work in Duval, St. Johns, Nassau, Baker, Clay, and Putnam counties, with interests including neighborhoods, education, aging adults, arts, women and girls, young children, and early literacy. Its 2024 grants had a median of $5,000, though amounts varied widely; most donor-advised grants are not open to applications, but eligible nonprofits can apply through competitive programs when application windows are open.

Harmony Healthcare Orlando Inc

Orlando, FL

Publix Super Markets Charities Inc

Lakeland, FL

Publix Super Markets Charities supports nonprofits addressing hunger, homelessness and housing, youth, education, and community needs in Florida, Georgia, Alabama, North Carolina, South Carolina, Tennessee, Virginia, and Kentucky. Its 2024 median grant was $2,500, though awards ranged widely; it accepts online requests from eligible organizations, with application periods varying by program.

Gulf Coast Community Foundation Inc

Venice, FL

Gulf Coast Community Foundation funds arts and culture, civic and economic development, education, the environment, health and human services, and disaster response, with a focus on its Florida service area. Community grants provide up to $25,000 per organization per fiscal year; larger catalytic grants are available, and 2025 grants had a median of $16,251. It accepts unsolicited requests through scheduled Community Grant cycles; catalytic grants start with a letter of inquiry, and initiative grants are by invitation only.