Lutheran Homes of South Carolina Foundation

John D Muller Jr Trust

Saint Louis, MO

Coastal Community Foundation of South Carolina Inc

N Charleston, SC

Coastal Community Foundation of South Carolina supports nonprofits and community initiatives in education, health, human services, the environment, arts, social justice, and community development across nine coastal South Carolina counties. Its 2024 itemized grants ranged from $5,057 to $2.3 million, with a median of $16,500; competitive programs accept applications through its online portal.

Central Carolina Community Foundation

Columbia, SC

Central Carolina Community Foundation funds education, human services, health, arts and culture, community development, disaster relief, and related community initiatives through specific grant programs. Its 2025 grants had a median of $20,000, and it primarily serves 11 Midlands counties while also funding statewide and nationally. It accepts applications through its online portal during published grant periods for specific opportunities; some programs are invitation-only.

Community Foundation of Greenville Inc

Greenville, SC

Community Foundation of Greenville funds nonprofits and projects in arts, education, environment, health, and human services, with a focus on Greenville County, South Carolina. Its 2026 Capacity Building Grants award $5,000–$12,500; 2024 grants had a median of $23,900. It accepts unsolicited requests through its Capacity Building Grants program.

South Carolina Christian Foundation

Spartanburg, SC

The foundation funds Christian ministries, churches, and quality-of-life organizations, with particular attention through its Community Trust Grants to Christian nonprofits in five South Carolina counties. Its 2024 grants had a median of $15,000, though awards varied widely; most grant dollars went to South Carolina, with additional funding in other states. Community Trust applicants must submit a Ministry Introduction Form and be invited to apply; the profile does not state whether other requests are unsolicited.

Spartanburg County Foundation

Spartanburg, SC

The Spartanburg County Foundation funds nonprofits and community groups serving Spartanburg County residents, with priorities including quality of life, education, economic mobility, and organizational capacity. Its itemized 2025 grants had a median of $15,500; listed programs offer awards of up to $10,000–$35,000.

United Community Bank Foundation

Greenville, SC

United Community Bank Foundation funds economic empowerment, arts, housing and youth development in communities served across Alabama, Florida, Georgia, North Carolina, South Carolina and Tennessee. Its 2025 grants ranged from $250 to $16,000, with a median of $2,000. It does not accept unsolicited requests; grants go to preselected organizations.

Milliken & Company Charitable Foundation

Spartanburg, SC

The Milliken & Company Charitable Foundation supports arts and economic development, inclusion, health and sustainability, and education and STEAM, in communities where Milliken operates. Most community grants are $10,000–$15,000, though reported 2025 grants ranged widely; applications are submitted online during its stated annual cycle.

Community Foundation of the Lowcountry

Hilton Head Island, SC

The Community Foundation of the Lowcountry funds nonprofits working in areas such as education, health, human services, community development, arts, and the environment. Its 2025 grants ranged from $5,000 to $1,234,463, with a median of $15,000; its service area covers Beaufort, Colleton, Hampton, and Jasper counties in South Carolina, with some grants limited to Hilton Head, Daufuskie, and Greater Bluffton. For competitive grants, organizations are directed to submit a Grant Inquiry Form; donor-advised fund grants are donor-recommended and have no application process.

Comporium Foundation Inc

Rock Hill, SC

Comporium Foundation supports education, community welfare, civic activity, health, economic development, trails, and religious organizations, primarily in South Carolina and North Carolina. Its 2024 grants ranged from $100 to $70,000, with a median of $3,625. It does not accept unsolicited requests and contributes only to preselected charitable organizations.

J M Smith Foundation

Spartanburg, SC

The J M Smith Foundation supports a range of charitable organizations, including churches, human services, education, arts, and animal welfare groups, primarily in South Carolina, with some grants in nearby states. In 2026, grants ranged from $200 to $28,200, with a median of $2,000. It funds only preselected organizations and does not accept unsolicited requests.

Gods Goods Mt Pleasant

Mt Pleasant, SC

GODS GOODS MT PLEASANT supports preselected charities working in areas such as Christian education and ministry, community development, and services for people facing poverty or abuse. Its 2025 grants ranged from $750 to $10,000, with a median of $5,000; most funding went to South Carolina, with smaller amounts awarded in several other states. It does not accept unsolicited requests.