Grand Strand Miracle League Inc

The CRPA Foundation Inc

Mount Pleasant, SC

South Carolina Cancer Alliance

Columbia, SC

The mission of the South Carolina Cancer Alliance(SCCA)is to reduce the impact of cancer on all South Carolinians.

Ocean View Memorial Foundation Inc

Myrtle Beach, SC

Extend grants and scholarships

J R Albert Charitable Trust

Charleston, SC

The trust supports charitable organizations addressing disaster relief, health care, disability services, hunger, education, trafficking, and other community needs. Its 2025 grants ranged from $5,000 to $32,000, with a median of $27,000, and went to organizations in several states, including South Carolina, Texas, Missouri, Virginia, Minnesota, and North Carolina. It funds only preselected organizations and does not accept unsolicited requests.

Lewis a Sikes Foundation

Tabor City, NC

The foundation funds education and scholarships, religion, arts, and support for children and people with autism or intellectual disabilities, primarily in North Carolina and also in South Carolina. In 2024, grants ranged from $350 to $10,537, with a median of $1,000. It gives only to preselected organizations and does not accept unsolicited requests.

Frances P Bunnelle Foundation Coastal Community Foundation of SC

Pawleys Island, SC

The Frances P. Bunnelle Foundation funds nonprofits and eligible public entities working to address poverty and basic needs, promote economic vitality, protect the environment, and support youth in Georgetown County, South Carolina. Common Good grants are available up to $15,000, Mini Grants range from $250 to $5,000, and Youth Board Grants are capped at $2,500. The Foundation does not accept unsolicited funding requests.

United Way of the Greater Triangle Inc

Durham, NC

United Way of the Greater Triangle funds nonprofits and community programs addressing poverty and advancing economic mobility, including work in education, family stability, health, housing, and youth development, primarily in Durham, Wake, Orange, and Johnston counties. Its 2025 grants had a median of about $25,000, while specific funds offer awards from up to $5,000 for crisis-related needs to $10,000–$50,000 for youth initiatives. It accepts applications for its open Bull City Future Fund and Neighbors Helping Neighbors Fund.

Truist Foundation Inc

Orlando, FL

The foundation funds nonprofit work that advances economic mobility and opportunity, especially workforce and career pathways, small-business support, and community development for low-to-moderate-income and disadvantaged people. Grants reach communities along the East Coast through Texas; the 2024 median grant was $25,000, though awards varied widely. It accepts unsolicited requests through an online application, with annual cycle deadlines of March 31, July 31, and November 30.

Coastal Community Foundation of South Carolina Inc

N Charleston, SC

The Coastal Community Foundation of South Carolina funds nonprofits through competitive grants for areas including education, health, community development, arts, and human needs. Its 2024 grants had a median of $16,500, with awards ranging from $5,057 to $2.3 million, across nine coastal South Carolina counties. It accepts applications only for listed competitive programs, through its online portal.

Central Carolina Community Foundation

Columbia, SC

Central Carolina Community funds education, human services, health, arts and culture, community development, disaster relief, and nonprofit capacity-building, primarily in the 11-county Midlands region of South Carolina, with some statewide and national grantmaking. Its 2025 grants had a median of $20,000; eligible nonprofits may apply through the online portal during published grant periods, though some opportunities are invitation-only.

Community Foundation of Greenville Inc

Greenville, SC

Community Foundation of Greenville funds nonprofits and projects in arts, education, environment, health, and human services, with a focus on Greenville County, South Carolina. Its 2026 Capacity Building Grants award $5,000–$12,500; 2024 grants had a median of $23,900. It accepts unsolicited requests through its Capacity Building Grants program.

South Carolina Christian Foundation

Spartanburg, SC

The foundation funds Christian ministries, churches, and quality-of-life organizations, with particular attention through its Community Trust Grants to Christian nonprofits in five South Carolina counties. Its 2024 grants had a median of $15,000, though awards varied widely; most grant dollars went to South Carolina, with additional funding in other states. Community Trust applicants must submit a Ministry Introduction Form and be invited to apply; the profile does not state whether other requests are unsolicited.