Angelman syndrome (AS) is a neurodevelopmental disorder characterized by global development delays and severe speech impairment. A few individuals with AS develop functional speech, but most communicate through a mixture of gestures, eye gaze, adapted sign language and augumentative communication devices. Individuals with AS have development delay and intellectual disabilities. Current research suggests that neuronal development occurs correctly in AS, but neuronal functioning is impaired. This neuronal impairment impacts the individual's ability to learn in that skills are acquired less rapidly than in age-matched peers. The Foundation for Angelman Syndrome therapeutics is an organization of families and professionals dedicated to finding a cure for AS and related disorders through the funding of an agressive research agenda, education, advocacy, and community support. Fast is committed to assisting individuals living with AS to realize their full potential and quality of life.
Key facts about Foundation for Angelman Syndrome
In short: Foundation for Angelman Syndrome gave $7.9M across 10 grants in 2024 (avg $792K), mostly in Pennsylvania. Source: 2024 IRS Form 990 filing.
- EIN
- 26-3160079
- Latest 990 filing
- Form 990 filing, 2024
- Annual giving (2024)
- $7,921,275
- Grants made (2024)
- 10
- Average grant
- $792,128
- Median grant
- $242,378
- Total assets
- $44,915,881
- Primary geography
- Pennsylvania (74% of itemized 2024 grant dollars)
Data from IRS Form 990 filing, 2024; updated September 2026.
Financial Overview
From 2024 IRS Form 990 filing · View filing
Total Assets
$44.9M
-23.1% YoY
Annual Giving
$7.9M
+42.2% YoY
Grant Count
10
-41.2% YoY
Avg Grant Size
$792K
+141.7% YoY
How Foundation for Angelman Syndrome gives
- Giving grew 172% from 2021 to 2024. Method
From the foundation's IRS Form 990 filings. Methodology.
About Foundation for Angelman Syndrome
Based on IRS filings
Foundation for Angelman Syndrome is a nonprofit organization focused on Medical Research, based in Austin, TX. IRS filing data is available from 2020 through 2024. As of 2024, the organization holds $44.9M in total assets. In 2024, it awarded 10 grants totaling $7.9M. Net investment income was $1.7M.
Focus Areas
Open Grants
5 open opportunities from Foundation for Angelman Syndrome
FAST IMPACT Award (Innovative Methods to Advance Angelman Syndrome Treatments Towards Clinical Trials)
Foundation for Angelman Syndrome
Amount
Up to $1,000,000 per year
Deadline
Rolling / Open
FAST Innovation Seed Grant
Foundation for Angelman Syndrome
Amount
$10,000 - $50,000
Deadline
Rolling / Open
FAST Postdoctoral Fellowship
Foundation for Angelman Syndrome
Amount
Up to $50,000 per year for up to two years
Deadline
Rolling / Open
Ready to take the next step with Foundation for Angelman Syndrome?
Geographic Focus
Where this funder awards grants
Grant Distribution by State
Share of all 10 itemized 2024 grant dollars.
States
Cities
Giving Over Time
Total grant dollars and number of grants per year
From 2020 to 2024, annual grant giving ranged from $800K (2022) to $7.9M (2024). In 2024 it made 10 grants totaling $7.9M.
Grant Insights
How this funder distributes its grants
Top Recipients
Top 9 recipients in 2024
The largest 2024 recipient was University of Pennsylvania ($5.9M). Together the top 9 received $7.9M.
Grant Size Distribution
43 grants across all recorded years
The most common grant size was in the $100–250K range: 13 grants of 43 (30%).
Giving History
Grant recipients and amounts by year
| Recipient | Purpose | Amount |
|---|---|---|
| University of Pennsylvania Philadelphia, PA | Upenn 2023: Research, Collaboration & License Agreement | $5,860,869 |
| Boston Children's Hospital Boston, MA | FT2022-006: Abom - Natural History Study | $470,957 |
| Rush University Medical Center Chicago, IL | Rush Coe | $320,500 |
| Duke University Charlotte, NC | FT2018-005 Amended: Gpic-Comm | $317,848 |
| Regents of the University of California Davis Davis, CA | Ft2022-007: gastrointestinal biomarkers in preclinical models of angelman syndrome | $274,044 |
| The Regents of the University of California San Francisco San Francisco, CA | Ft2023-002: developing a crispra therapy for the classi/ii deletion genotype of angelman syndrome | $210,711 |
| Brown University Providence, RI | Ft2022-005: development of bdnf potentiating therapeutics for motor and cognitive dysfunction in as | $150,000 |
| Children's Research Institute Washington, DC | Ft2022-003: peak alpha frequency as an eeg biomarker for angelman syndrome | $140,846 |
| Keck Graduate Institute of Applied Life Sciences Claremont, CA | Ft2022-002: targeting angelman syndrome therapeutics to the brain utilizing novel cell penetrating peptides | $125,000 |
| Brown University Providence, RI | PD2023-001: Postdoctoral Fellowship Program | $50,500 |
Financial History
Multi-year comparison from IRS filings
| Metric | 2024 | 2023 | 2022 |
|---|---|---|---|
| Total Assets | $44,915,881 | $58,430,242 | $63,075,354 |
| Revenue | $5,388,260 | $6,525,815 | $52,477,819 |
| Expenses | $10,391,969 | $23,229,158 | $8,933,021 |
| Qualifying Distributions | — | — | — |
| Net Investment Income | $1,677,094 | $2,734,710 | $47,780,150 |
| Distributable Amount | — | — | — |
Data update history
When this profile's IRS filing data changed on Grantable
- IRS filings on file for fiscal years 2020–2024
Leadership & Key People
Officers and directors from IRS filings
Foundation for Angelman Syndrome is led by Alana Newhouse, President & CEO on every filing since 2022; 4 of 16 officers listed in 2024 are compensated.
Officers on the 2024 filing
Alana Newhouse
President & CEO
On filings since 2022
40 hrs/week
$50K (2022) → $245K (2024)
Ryan Jacob
Chairperson
Director → Chairperson, 2023
On filings since 2021
18 hrs/week
No compensation reported
Ben O'Connor
Director
Director → Treasurer, 2021
Treasurer → Director, 2022
On filings since 2020
5 hrs/week
No compensation reported
Kelly David
Director
Director → Co-Vice Chairperson, 2021
Co-Vice Chairperson → Director, 2024
On filings since 2020
10 hrs/week
No compensation reported
Lauren Hoffer
Director
On filings since 2020
5 hrs/week
No compensation reported
Roy Azout
Director
On filings since 2020
5 hrs/week
No compensation reported
Nora Xu
Director
On filings since 2021
5 hrs/week
No compensation reported
John Schlueter
Director
On filings since 2023
15 hrs/week
No compensation reported
Karly Warner
Director
New on the 2024 filing
5 hrs/week
No compensation reported
Ryan K. Fischer
Chief Operating Oficer
On filings since 2023
40 hrs/week
$198K (2023) → $286K (2024)
Kena Pearson
Chief Financial Officer
New on the 2024 filing
40 hrs/week
$233K (2024)
Michele Golombuski
Chief Development Officer
New on the 2024 filing
40 hrs/week
$210K (2024)
Allyson Berent
Chief Science Officer
On filings since 2020
2 hrs/week
No compensation reported
Amelia Beatty
Secretary
Director → Secretary, 2022
On filings since 2020
15 hrs/week
No compensation reported
Michael Hanrahan
Vice Chairperson
Co-Vice Chairperson → Vice Chairperson, 2024
On filings since 2023
10 hrs/week
No compensation reported
Guy Shapiral
Tresurer
New on the 2024 filing
15 hrs/week
No compensation reported
Former officers (11)
- Former: Kena Richert (2020–2023) — Chief Financial Officer
- Former: Kristy Dixon (2020–2023) — Tresurer
- Former: Maiddy Dunigan (2020–2023) — Former Officer & COO
- Former: Megan Cross (2021–2023) — Chief Information Officer
- Former: John Schuellter (2020–2022) — Chairperson
- Former: Paula Evans (2020–2022) — Former Officer & Director
- Former: Sam Maydew (2020–2021) — Director
- Former: Bryan Thompson (2020) — Director
- Former: Chloe Knouff (2020) — Director
- Former: David Gurzick (2020) — Director
- Former: Debbie Guagliardo (2020) — Former Officer & Director
Data from IRS Form 990 filings, 2020–2024. "On filings since" is the earliest filing we hold that lists the person; hours are average hours per week as reported.
Compensation Overview
From 2024 IRS filing
The highest reported compensation on the 2024 filing was $286K, to Ryan K Fischer (Chief Operating Oficer). 4 officers or directors reported compensation on that filing.
Frequently asked questions about Foundation for Angelman Syndrome
How much does Foundation for Angelman Syndrome give each year?
Foundation for Angelman Syndrome gave $7.9M across 10 grants in 2024, according to its 2024 IRS Form 990 filing. In 2023 it gave $5.6M across 17 grants.
What is Foundation for Angelman Syndrome's typical grant size?
Foundation for Angelman Syndrome's median grant in 2024 was $242,378, and its average grant was $792,128, across 10 grants on its 2024 IRS Form 990 filing.
Where does Foundation for Angelman Syndrome give grants?
Foundation for Angelman Syndrome gives mostly in Pennsylvania: 74% of the grant dollars itemized on its 2024 IRS Form 990 filing went to recipients there. The next largest states were California (8%) and Massachusetts (6%). The most frequent recipient cities were Providence, RI (2 grants).
Does Foundation for Angelman Syndrome give general operating support?
Not in 2024: none of the 10 grants with a stated purpose on Foundation for Angelman Syndrome's 2024 IRS Form 990 filing were described as general or operating support.
Who are Foundation for Angelman Syndrome's largest grantees?
Foundation for Angelman Syndrome's largest 2024 grantees include University of Pennsylvania ($5,860,869), Boston Children's Hospital ($470,957) and Rush University Medical Center ($320,500), according to its 2024 IRS Form 990 filing. Together they received 84% of its itemized 2024 grant dollars.
How large is Foundation for Angelman Syndrome?
Foundation for Angelman Syndrome reported $44.9M in total assets on its 2024 IRS Form 990 filing. Its revenue that year was $5.4M.
What is Foundation for Angelman Syndrome?
Foundation for Angelman Syndrome is a nonprofit organization focused on Medical Research, based in Austin, TX. It holds $44.9M in total assets as of 2024.
What is Foundation for Angelman Syndrome's EIN?
Foundation for Angelman Syndrome's EIN (Employer Identification Number) is 26-3160079. IRS Form 990 filing data is available on this page for 2020–2024.
Data last updated September 2026. Sourced from IRS Form 990 filings.
Here's the math on researching Foundation for Angelman Syndrome by hand.
Explore Open Grants
Browse active grant opportunities in Foundation for Angelman Syndrome's focus areas in our free grants database
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Foundation for Angelman Syndrome down — hundreds of funders to go?