Biloxi Regional Medical Center Inc

Gulf Coast Community Foundation Inc

Gulfport, MS

Gulf Coast Community Foundation supports education, arts and culture, historic preservation, neighborhood enrichment, and health and human services, primarily benefiting the Mississippi Gulf Coast and South Mississippi. Its 2024 grants ranged from $5,237 to $1.52 million, with a median of $10,000; several specific fund programs offer grants up to $2,000–$2,500. The profile does not state whether it accepts unsolicited requests.

Enterprise Holdings Foundation

Saint Louis, MO

Enterprise Holdings Foundation supports nonprofits in health, education, arts, disaster relief, reforestation, hunger relief, and community equity, with an emphasis on organizations actively supported by Enterprise employees and their families. Its reported grants range widely: 2024 giving averaged about $7,700 across 9,499 grants, while the foundation also offers awards of up to $40,000; it supports communities where Enterprise operates worldwide. Unsolicited requests are accepted at any time, but eligible applications must be submitted by an Enterprise team member or their spouse or domestic partner on behalf of a nonprofit they actively support.

MGM Resorts Foundation

Las Vegas, NV

The MGM Resorts Foundation funds one-year grants to nonprofits providing essential services, including housing, workforce development, education, food, health, and family support. In 2025, grants ranged from $5,200 to $128,542, with a median of $13,019; funding focuses on communities where MGM employees live and work, especially Nevada. It describes a proposal-review process through regional Community Grant Councils but does not state whether unsolicited requests are accepted.

Asbury Foundation of Hattiesburg Inc

Hattiesburg, MS

The Asbury Foundation supports Asbury-related benevolent care, capital projects, education, innovation, special programs, and other priorities; it also reported a 2024 grant for a Hattiesburg food pantry. Its 2024 giving was one grant of $873, and eligible applicants must serve one of eight named Mississippi counties. The filing describes an application process but does not say whether unsolicited requests are accepted.

Robert M Hearin Foundation

Ridgeland, MS

Mississippi Power Foundation Inc

Gulfport, MS

The foundation funds education, community relations, economic development, and environmental efforts, primarily in Mississippi, though it also made grants in Maine, New York, Ohio, and Massachusetts. Its typical award was about $10,000 in 2025 (median), with grants ranging from $400 to $400,500; the profile does not state whether it accepts unsolicited requests.

Kelly Gene Cook Sr Charitable Foundation

Houston, TX

The foundation funds charitable, religious, educational, and scientific organizations, with recent grants supporting scholarships, schools, disability services, and children’s programs. In 2024 it awarded 64 grants totaling about $2 million; grants ranged from $2,204 to $223,786, with a median of $9,317. Most 2024 funding went to Mississippi, followed by Texas and Louisiana; the foundation does not limit giving to preselected organizations, and its filing provides application details in “Statement 11.”

Ergon Foundation Inc

Jackson, MS

The foundation funds medical research, education, community development, and services for children with communication disorders, with most giving in Mississippi. In 2025, its grants ranged from $2,500 to $615,000, with a median of $25,000. It gives only to preselected charitable organizations and does not accept unsolicited funding requests.

Pinebelt Foundation

Hattiesburg, MS

Pinebelt Foundation supports charitable activities, community programs, and scholarships, with grants spanning varied local needs. In 2025, its grants had a median of $10,000, though amounts varied widely; its primary focus is the Pine Belt of South Mississippi. It accepts applications through GOapply for listed grant programs.

Laura C Higdon Charitable Foundation

Jackson, MS

The foundation funds scholarships for individuals in Escambia County, Alabama, and Santa Rosa County, Florida. Its 2025 grants ranged from $500 to $2,000, with a median of $1,000; the profile does not state whether it accepts unsolicited requests.

Community Foundation for Mississippi

Jackson, MS

The Community Foundation for Mississippi funds nonprofits and charitable projects, with competitive grants focused on placemaking, children and families, and community partnerships, alongside donor- and fund-directed support for a range of causes. In 2025, grants ranged from $5,500 to $800,000, with a median of $19,500; specific programs offer up to $5,000 or $5,000–$15,000. Its main service area is 22 counties in central and southwest Mississippi, though some fund grants can support eligible organizations nationwide; the profile does not state whether it accepts unsolicited requests.

Community Foundation of Northwest Mississippi

Hernando, MS

The Community Foundation of Northwest Mississippi funds nonprofit and public-sector work in education, children’s health, workforce development, food security, and other charitable areas, with competitive programs focused on early childhood, regional development, civic engagement, and education technology. Its 2024 grants ranged from $5,500 to $962,000, with a median of about $13,900, and primarily serve 12 counties in Northwest Mississippi. It accepts applications through its competitive-grant portal; individual grants or loans are not available.