Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding - Cycle 3 Grant

Patient-Centered Outcomes Research Institute

Funding Amount

Up to US $750,000

Deadline

Rolling / Open

Grant Type

foundation

Overview

Improving Methods for Conducting Patient - Centered Comparative Clinical Effectiveness Research PCORI Funding - Cycle 3 Grant

Status: ACTIVE
Funder: Patient-Centered Outcomes Research Institute
Amount: Up to US $750,000
Last Updated: January 18, 2026

Summary

The Patient-Centered Outcomes Research Institute (PCORI) is funding Cycle 3 to enhance patient-centered comparative clinical effectiveness research (CER). This initiative targets critical methodological gaps, focusing on improving the use of artificial intelligence, study design, data research networks, and ethical protections. By addressing these areas, PCORI aims to strengthen the quality of evidence in CER, thus promoting better outcomes in healthcare decision-making.

Overview

Improving Methods for Conducting Patient-Centered Comparative Clinical Effectiveness Research PCORI Funding- Cycle 3 With this PCORI Funding Announcement (PFA), PCORI aims to fund studies that address high-priority methodological gaps in patient-centered comparative clinical effectiveness research (CER). For this Cycle Methods PFA, PCORI has identified the following areas as programmatic priorities that address important methodological gaps and lead to improvements in the strength and quality of evidence generated by CER studies: Methods To Improve the Use of Artificial Intelligence (AI) and Machine Learning (ML) in Clinical Research.  Methods To Improve Study Design. Methods To Support Data Research Networks. Methods Related to Ethical and Human Subjects Protections Issues in Patient-Centered CER.

Eligibility

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Focus Areas & Funding Uses

Fields of Work

science-researchhealthcare

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