DIPG: Game Changer Grant

DIPG: Game Changer Grant

Status: ACTIVE
Funder: Chadtough Defeat Dipg Foundation
Amount: Up to US $600,000
Last Updated: October 22, 2025

Summary

The ChadTough Defeat DIPG Game Changer Grant aims to support innovative research projects focused on DIPG/DMG, providing up to $600,000 over three years. This funding is intended for hypothesis-driven research that addresses significant challenges in the field, with the potential for groundbreaking discoveries. Proposals are encouraged from both individual and collaborative teams, fostering advancements in understanding and treating this devastating childhood brain cancer.

Overview

We at ChadTough see a world where kids diagnosed with DIPG/DMG have a bright future and can live out their dreams. To make this vision a reality, we are committed to funding the most innovative, promising research on childhood brain cancer. The foundation's founding families, the Carrs and the Mosiers, lost their sons, 5-year-old Chad and 6-year-old Michael, in 2015 to DIPG. Now, also fueled by other parents who have faced a pediatric brain cancer diagnosis, our Family Partners, and guided by a Scientific Advisory Council made up of the leading experts in the field, the ChadTough Defeat DIPG Foundation ensures every dollar possible funds the most incremental, promising research available anywhere in the world. Game Changer Grant Description The ChadTough Defeat DIPG Game Changer Grant provides three years of funding for hypothesis-driven research projects. The proposed research must represent an innovative approach to a major challenge in DIPG/DMG research. The funded projects must have the potential to lead to groundbreaking discoveries in the field and transform our understanding of the tumorigenesis process or our ability to treat or detect DIPG. We welcome both single investigator and collaborative, multi-institutional research proposals. For collaborative proposals, a Primary Investigator must be identified with other participants listed as collaborating researchers. Both single-investigator and collaborative proposals will be evaluated based on their scientific merit. The ChadTough Defeat DIPG Game Changer Grant is up to $600,000 over 3 years (maximum of $200,000 per year). Conditions of Grants We fund research to better understand the causes of DIPG/DMG and to advance its treatment and cure. To help achieve this goal, we expect researchers to publish their findings in peer-reviewed journals and to make their data available to other researchers.All grants are payable to the grant recipient’s institution or laboratory.Overlap in funding is not permitted. This includes scientific, budget, and commitment overlap, as defined by the National Institute of Health.Requests for transfers to another institution while the grant is in effect will be considered on a case-by-case basis.Grant recipients will work with the foundation to coordinate a joint press release to announce the grant.

Eligibility

You can learn more about this opportunity by visiting the funder's website. Applicant must hold an M.D. and/or Ph.D. by the application deadline. Applicant must be employed by an academic institution, nonprofit research institution, or laboratory. Applicant need not be a U.S. citizen.

Ineligibility

No funds may be used for indirect costs.