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Development of Collaborative Research Facilities or Research-Resource Facilities (C06 Clinical Trial Not Allowed)

National Institutes of Health

Funding Amount

$2,000,000 - $8,000,000

Deadline

January 25, 2028

657 days left

Grant Type

federal

Overview

Development of Collaborative Research Facilities or Research-Resource Facilities (C06 Clinical Trial Not Allowed)

This Notice of Funding Opportunity (NOFO) solicits applications to develop shared-use research facilities or research-supporting facilities that enable collaborative research and benefit broad research communities at large. The NOFO supports two existing construction programs: the Biomedical Research Facilities (BRF) program and the HIV/AIDS Research Facilities (HRF) program.The BRF program supports the construction or modernization of biomedical research facilities that advance basic, translational, clinical, or behavioral science research in all areas. Intended facilities include shared research spaces, core facilities, biorepositories, or other shared-use resource facilities that serve a broad scientific community with a significant, long-term impact on biomedical research.The HRF program funds the development of HIV/AIDS research or research-supporting resources that the empowered research activities must align with the NIH Office of AIDS Research (OAR) priorities, as outlined at OAR HIV/AIDS Research Priorities, including research focusing on the long-term health consequences of HIV infection.NIH encourages applications from institutions across all geographic regions of the country, including Institutions of Emerging Excellence (IEE) in biomedical research, to strengthen the nation"s research capacity.

Details

  • Agency: National Institutes of Health
  • Department: Department of Health and Human Services
  • Opportunity #: PAR-26-106
  • Total Funding: $88,000,000
  • Expected Awards: 14
  • Instrument: grant

Eligibility

See Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Eligibility

Eligible Applicant Types

county_governmentsindependent_school_districtscity_or_township_governmentsother_native_american_tribal_organizationsfor_profit_organizations_other_than_small_businessesnonprofits_non_higher_education_with_501c3public_and_indian_housing_authoritiesnonprofits_non_higher_education_without_501c3state_governmentsotherpublic_and_state_institutions_of_higher_educationprivate_institutions_of_higher_educationfederally_recognized_native_american_tribal_governmentssmall_businessesspecial_district_governments

How to Apply

PAR-26-106-Revised-Full-Announcement.html

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<title>PAR-26-106: Development of Collaborative Research Facilities or Research-Resource Facilities (C06 Clinical Trial Not Allowed)</title>

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<div id="page-title" class="heading1" tabindex="0">Department of Health and Human Services</div>

<div>

<div data-element-id="259457" data-element-has-label="false" data-element-required="false" data-element-has-value="true" data-section-code="OI" data-element-type="TEXT">
<a id='_bookmark259457' tabindex='-1' aria-hidden='true'></a><a name="_Part 1. Overview Information"></a><h1>Part 1. Overview Information</h1>
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<a id='_bookmark259458' tabindex='-1' aria-hidden='true'></a>Participating Organization(s)
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<p>National Institutes of Health (<a href="http://www.nih.gov">NIH</a>)</p>
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<p>NATIONAL INSTITUTES OF HEALTH (<a href="https://www.nih.gov/" target="_blank" rel="noreferrer">NIH</a>)
<p>Office of AIDS Research (<a href="https://www.oar.nih.gov/" target="_blank" rel="noreferrer">OAR</a>)
</p>
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<a id='_bookmark259460' tabindex='-1' aria-hidden='true'></a><p>Division of Program Coordination, Planning and Strategic Initiatives, Office of Research Infrastructure Programs (<a href="https://orip.nih.gov/">ORIP</a>)</p>
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<a id='_bookmark259461' tabindex='-1' aria-hidden='true'></a>Funding Opportunity Title
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<div class=" col-md-8 datacolumn">
<span class="title">Development of Collaborative Research Facilities or Research-Resource Facilities (C06 Clinical Trial Not Allowed)</span>
</div>
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<div class="col-md-4 datalabel" tabindex="0" data-element-id="259462" data-element-required="true" data-element-has-value="true" data-section-code="OI" data-element-type="TEXT">
<a id='_bookmark259462' tabindex='-1' aria-hidden='true'></a>Activity Code
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<a href="http://grants.nih.gov/grants/funding/ac_search_results.htm?text_curr=c06&amp;Search.x=0&amp;Search.y=0&amp;Search_Type=Activity">C06</a> Research Facilities Construction Grant
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<div class="col-md-4 datalabel" tabindex="0" data-element-id="259463" data-element-required="true" data-element-has-value="true" data-section-code="OI" data-element-type="LINKED_ELEMENT">
<a id='_bookmark259463' tabindex='-1' aria-hidden='true'></a>Announcement Type
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<div class=" col-md-8 datacolumn">
Reissue of

PAR-25-061



<br/>
</div>
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<a id='_bookmark259464' tabindex='-1' aria-hidden='true'></a>Related Notices
</div>
<div class=" col-md-8 datacolumn">
<ul><li>Check for any recent <a href="https://grants.nih.gov/grants/guide/url_redirect.php?id=11163">Notices of NIH Policy Changes</a> that may impact application requirements.</li></ul>
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<div class="col-md-4 datalabel" tabindex="0" data-element-id="259465" data-element-required="true" data-element-has-value="true" data-section-code="OI" data-element-type="LINKED_ELEMENT">
<a id='_bookmark259465' tabindex='-1' aria-hidden='true'></a>Funding Opportunity Number (FON)
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<div class=" col-md-8 datacolumn">
<span class="noticenum">PAR-26-106</span>
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</div>

<div class="row" data-index="10">
<div class="col-md-4 datalabel" tabindex="0" data-element-id="259466" data-element-required="true" data-element-has-value="true" data-section-code="OI" data-element-type="LINKED_ELEMENT">
<a id='_bookmark259466' tabindex='-1' aria-hidden='true'></a>Companion Funding Opportunity
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<div class=" col-md-8 datacolumn">
None
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<div class="row" data-index="11">
<div class="col-md-4 datalabel" tabindex="0" data-element-id="259467" data-element-required="true" data-element-has-value="true" data-section-code="OI" data-element-type="TEXT">
<a id='_bookmark259467' tabindex='-1' aria-hidden='true'></a>Number of Applications
</div>
<div class=" col-md-8 datacolumn">
<p>See Section III. 3. Additional Information on Eligibility.</p>
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<div class="col-md-4 datalabel" tabindex="0" data-element-id="259468" data-element-required="true" data-element-has-value="true" data-section-code="OI" data-element-type="LINKED_ELEMENT">
<a id='_bookmark259468' tabindex='-1' aria-hidden='true'></a>Assistance Listing Number(s)
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<div class=" col-md-8 datacolumn">
93.352, 93.310
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<div class="row" data-index="13">
<div class="col-md-4 datalabel" tabindex="0" data-element-id="259469" data-element-required="true" data-element-has-value="true" data-section-code="OI" data-element-type="TEXT">
<a id='_bookmark259469' tabindex='-1' aria-hidden='true'></a>Funding Opportunity Purpose
</div>
<div class=" col-md-8 datacolumn">
<p>This Notice of Funding Opportunity (NOFO) solicits applications to develop shared-use research facilities or research-supporting facilities that enable collaborative research and benefit broad research communities at large. The NOFO supports two existing construction programs: the Biomedical Research Facilities (BRF) program and the HIV/AIDS Research Facilities (HRF) program.</p><p>The BRF program supports the construction or modernization of biomedical research facilities that advance basic, translational, clinical, or behavioral science research in all areas. Intended facilities include shared research spaces, core facilities, biorepositories, or other shared-use resource facilities that serve a broad scientific community with a significant, long-term impact on biomedical research.</p><p>The HRF program funds the development of HIV/AIDS research or research-supporting resources that the empowered research activities must align with the NIH Office of AIDS Research (OAR) priorities, as outlined at <a href="https://www.oar.nih.gov/hiv-policy-and-research">OAR HIV/AIDS Research Priorities</a>, including research focusing on the long-term health consequences of HIV infection.</p><p>NIH encourages applications from institutions across all geographic regions of the country, including Institutions of Emerging Excellence (IEE) in biomedical research, to strengthen the nation&#146;s research capacity.</p>
</div>
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<div class="row" data-index="14">
<div class="col-md-4 datalabel" tabindex="0" data-element-id="259470" data-element-required="true" data-element-has-value="true" data-section-code="OI" data-element-type="TEXT">
<a id='_bookmark259470' tabindex='-1' aria-hidden='true'></a>Funding Opportunity Announcement Goal(s)
</div>
<div class=" col-md-8 datacolumn">
<p>The Office of Research Infrastructure Programs (ORIP) is a program office in the Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI) dedicated to supporting research infrastructure and related research resource programs. ORIP consists of the Division of Comparative Medicine (DCM) and the Division of Construction and Instruments (DCI).</p>
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<a id='_bookmark259471' tabindex='-1' aria-hidden='true'></a><a name="_Key Dates"></a><h2>Key Dates</h2>
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<a id='_bookmark259472' tabindex='-1' aria-hidden='true'></a>Posted Date
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<div class=" col-md-8 datacolumn">
<p>March 6, 2026</p>
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<a id='_bookmark259473' tabindex='-1' aria-hidden='true'></a>Open Date (Earliest Submission Date)
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March 06, 2026
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<th scope="col" colspan="3" style="border:2px solid #bcbcbc;" class="text-center">Application Due Dates</th>
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<th scope="col" style="width:16.66%;border-left:2px solid #bcbcbc;" class="text-center">New</th>
<th scope="col" style="width:16.66%" class="text-center">Renewal / Resubmission / Revision (as allowed)</th>
<th scope="col" style="width:16.66%;border-right:2px solid #bcbcbc;" class="text-center">AIDS - New/Renewal/Resubmission/Revision, as allowed</th>
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April 06, 2026
</td>
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Not Applicable
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<td>
Not Applicable
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<td>July 2026</td>
<td> October 2026

</td>
<td>December 2026</td>
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<td>
January 25, 2027
</td>
<td>
Not Applicable
</td>
<td>
Not Applicable
</td>
<td>June 2027</td>
<td> October 2027

</td>
<td>December 2027</td>
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<tr>
<td>
January 25, 2028
</td>
<td>
Not Applicable
</td>
<td>
Not Applicable
</td>
<td>June 2028</td>
<td> October 2028

</td>
<td>December 2028</td>
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<a id='_bookmark259477' tabindex='-1' aria-hidden='true'></a><p>All applications are due by 5:00 PM local time of applicant organization.</p>

<p>Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.</p>
</div>
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<div class="col-md-push-4 col-md-8 datacolumn">

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<div class="col-md-4 datalabel" tabindex="0" data-element-id="259482" data-element-required="true" data-element-has-value="true" data-section-code="KD" data-element-type="DATE">
<a id='_bookmark259482' tabindex='-1' aria-hidden='true'></a>Expiration Date
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<div class=" col-md-8 datacolumn">
January 26, 2028
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<div class="col-md-4 datalabel" tabindex="0" data-element-id="259483" data-element-required="true" data-element-has-value="true" data-section-code="KD" data-element-type="TEXT">
<a id='_bookmark259483' tabindex='-1' aria-hidden='true'></a>Due Dates for E.O. 12372
</div>
<div class=" col-md-8 datacolumn">
<p>As described in the <a href="http://grants.nih.gov/grants/guide/url_redirect.htm?id=11115">NIH Grants Policy Statement</span></a>, an applicant must provide a copy of the application to the State Single Point of Contact (SPOC) no later than the time the application is submitted to NIH. SPOC comments must be submitted to NIH with the application, or the application must indicate the date on which the application was provided to the SPOC for review.</p>
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<a id='_bookmark259484' tabindex='-1' aria-hidden='true'></a>Required Application Instructions
</div>

<div data-element-id="259484" data-element-has-label="true" data-element-required="true" data-element-has-value="true" data-section-code="KD" data-element-type="TEXT">
<p>It is critical that applicants follow the instructions in the Research (R) Instructions in the <a href="https://grants.nih.gov/grants/guide/url_redirect.htm?id=82400">How to Apply - Application Guide</a>, except where instructed to do otherwise (in this NOFO or in a Notice from <a href="http://grants.nih.gov/grants/guide/url_redirect.htm?id=11164">NIH Guide for Grants and Contracts</a>).</p><p>Conformance to all requirements (both in the Application Guide and the NOFO) is required and strictly enforced. Applicants must read and follow all application instructions in the Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions.</p><p><strong>Applications that do not comply with these instructions may be delayed or not accepted for review.</strong></p>
</div>

<div data-element-id="262224" data-element-has-label="false" data-element-required="true" data-element-has-value="true" data-section-code="KD" data-element-type="TEXT">
<a id='_bookmark262224' tabindex='-1' aria-hidden='true'></a><p style="margin-left:0in;">There are several options available to submit your application through Grants.gov to NIH and Department of Health and Human Services partners. You <strong>must</strong> use one of these submission options to access the application forms for this opportunity.</p><ol><li>Use the&nbsp;<a href="https://public.era.nih.gov/assist/landing.era?tabId=0819b5fc-46b7-4f02-b6b7-127e5a4e19fa">NIH ASSIST system</a> to prepare, submit and track your application online.</li><li>Use an institutional system-to-system (S2S) solution to prepare and submit your application to Grants.gov and&nbsp;<a href="https://public.era.nih.gov/commons/">eRA Commons</a> to track your application. Check with your institutional officials regarding availability.</li><li>Use&nbsp;<a href="https://grants.gov/search-grants?oppStatuses=closed|archived|posted|forecasted&amp;fon=PA-25-301">Grants.gov</a> Workspace to prepare and submit your application and&nbsp;<a href="http://public.era.nih.gov/commons/">eRA Commons</a> to track your application.</li></ol>
</div>

<div id="tocDiv">
<div class="heading1" tabindex="0">Table of Contents</div>
<div class="toc-link"><a href="#_Part%201.%20Overview%20Information">Part 1. Overview Information</a></div><div class="toc-link P_SingleIndent"><a href="#_Key%20Dates">Key Dates</a></div><div class="toc-link"><a href="#_Part%202.%20Full%20Text%20of%20Announcement">Part 2. Full Text of Announcement</a></div><div class="toc-link P_SingleIndent"><a href="#_Section%20I.%20Notice%20of%20Funding%20Opportunity%20Description">Section I. Notice of Funding Opportunity Description</a></div><div class="toc-link P_SingleIndent"><a href="#_Section%20II.%20Award%20Information">Section II. Award Information</a></div><div class="toc-link P_SingleIndent"><a href="#_Section%20III.%20Eligibility%20Information">Section III. Eligibility Information</a></div><div class="toc-link P_SingleIndent"><a href="#_Section%20IV.%20Application%20and%20Submission%20Information">Section IV. Application and Submission Information</a></div><div class="toc-link P_SingleIndent"><a href="#_Section%20V.%20Application%20Review%20Information">Section V. Application Review Information</a></div><div class="toc-link P_SingleIndent"><a href="#_Section%20VI.%20Award%20Administration%20Information">Section VI. Award Administration Information</a></div><div class="toc-link P_SingleIndent"><a href="#_Section%20VII.%20Agency%20Contacts">Section VII. Agency Contacts</a></div><div class="toc-link P_SingleIndent"><a href="#_Section%20VIII.%20Other%20Information">Section VIII. Other Information</a></div>
</div><br/>

<div data-element-id="259486" data-element-has-label="false" data-element-required="true" data-element-has-value="true" data-section-code="FOD" data-element-type="TEXT">
<a id='_bookmark259486' tabindex='-1' aria-hidden='true'></a><a name="_Part 2. Full Text of Announcement"></a><h1>Part 2. Full Text of Announcement</h1>
</div>

<div data-element-id="259487" data-element-has-label="false" data-element-required="true" data-element-has-value="true" data-section-code="FOD" data-element-type="TEXT">
<a id='_bookmark259487' tabindex='-1' aria-hidden='true'></a><a name="_Section I. Notice of Funding Opportunity Description"></a><h2>Section I. Notice of Funding Opportunity Description</h2>
</div>

<div data-element-id="259488" data-element-has-label="false" data-element-required="true" data-element-has-value="true" data-section-code="FOD" data-element-type="TEXT">
<a id='_bookmark259488' tabindex='-1' aria-hidden='true'></a><p>The NIH Office of Research Infrastructure Programs (ORIP) administers two extramural construction programs: the Biomedical Research Facilities (BRF) program and the HIV/AIDS Research Facilities (HRF) program. These programs support the construction and modernization of biomedical research facilities that advance basic, translational, clinical, or behavioral science research, including those dedicated to the HIV/AIDS research. The primary goal of this NOFO is to support the development of modern, shared-use facilities that enhance collaborative biomedical research with broad and high impact, create research training opportunities, cultivate the future generations of the biomedical research workforce, and sustain critical biomedical research resources for broad and long-lasting impact.</p><p>The BRF program solicits applications from eligible higher education and research institutions to construct new or modernize existing shared-use research facilities. BRF facilities support biomedical and behavioral research in all scientific areas, especially research in emerging scientific areas with strong potential for impact. Supported facilities must serve a wide research community, locally (within the applicant institution), regionally (across several institutions), or nationally, demonstrating value beyond a single research group or department. Appropriate facilities include but are not limited to: institution-wide multidisciplinary collaborative research spaces, core laboratories, state-of-the-art facilities to house advanced technologies such as imaging centers, biorepositories, and other shared-use facilities that support emerging new approach methodologies or human-based research technologies. Additionally, these facilities can play a crucial role in advancing implementation science by providing the physical infrastructure necessary to develop, test, refine, and scale evidence-based interventions, ensuring their effective integration into real-world applications. Facilities that solely or primarily focus on supporting animal research or animal care activities are not among the priorities of this NOFO.</p><p>The HRF program supports the development or modernization of shared-use research facilities that the supported research must align with the&nbsp;<a href="https://www.oar.nih.gov/hiv-policy-and-research">HIV/AIDS research priorities</a> established by the NIH Office of AIDS Research (OAR). These facilities are expected to strengthen a sustainable infrastructure that enables cutting-edge, collaborative biomedical and behavioral HIV/AIDS research, enhances preservation and advancement of critical HIV/AIDS research resources, and offers robust training opportunities to foster the next generation of HIV/AIDS researchers.</p><p>This NOFO encourages applications from eligible institutions across all geographic regions of the country, including Institutions of Emerging Excellence (IEEs) in biomedical research, as defined in&nbsp;<a href="https://uscode.house.gov/view.xhtml?req=granuleid:USC-prelim-title42-section283k&amp;num=0&amp;edition=prelim#:~:text=development%20and%20training.-,(D)%20The%20applicant,-%2D">42 USC 283k(c)(2)(D)</a>, to contribute to strengthening our nation&#146;s biomedical research capability. All proposed projects must align with an institution&#146;s current infrastructure and long-term strategic vision and demonstrate lasting benefit for the broader research community. Successful projects are expected to provide shared, collaborative environments that advance a broad range of research teams and promote institutional excellence. Laboratory spaces dedicated solely to individual investigators or single research groups are not supported under this NOFO.</p><p>NIH intends to allocate at least 25% of the funds appropriated to the BRF program to support IEE projects. IEEs are expected to have demonstrated emerging excellence in a biomedical or behavioral research field and are located in a geographic area facing significant public health challenges, such as limited access to healthcare services or inadequate research infrastructure.&nbsp;Per&nbsp;<a href="https://uscode.house.gov/view.xhtml?req=granuleid:USC-prelim-title42-section283k&amp;num=0&amp;edition=prelim#:~:text=development%20and%20training.-,(D)%20The%20applicant,-%2D">42 USC 283k(c)(2)(D)</a><u>, eligible IEEs must be actively engaged in addressing the health deficit of the populations they serve.</u>&nbsp;While many IEEs reside in regions that traditionally receive fewer NIH or other federal research grants, such as Institutional Development Award (IDeA)-eligible states, geographic location alone does not determine IEE eligibility. For example, an institution in a non-IDeA state may qualify if it lacks essential research infrastructure and demonstrates a focused, mission-driven effort to advance research in areas aligned with the unmet health needs of its local population.</p><p>For the BRF program, to be considered as an IEE under this NOFO, an applicant institution must explicitly identify itself as such and justify its status in the Project Narrative section. IEE applicants must clearly articulate the biomedical or behavioral research focus they are striving to establish or expand and describe how the proposed facility project will significantly advance that goal. Applications should also demonstrate how the institution is building research capacity and training the next generation of scientists to address regional health deficit. While IEE faculty is expected to dedicate significant time to teaching, this NOFO does not support projects with purely instructional or didactic activities.</p><p>NIH recognizes that cutting-edge physical infrastructures are essential for the conduct of novel, advanced research and the support of specialized research-enabling operations. Dedicated collaborative research facilities and shared-use resource spaces, such as clean rooms for barrier housing or GLP-compliant spaces for compound synthesis, as well as biosafety-level laboratories for research involving human participants, are critical to support specialized equipment and technologies, emerging experimental protocols, and enhance institutional research capacity. Modern physical infrastructure necessitates the implementation of advanced engineering designs that comply with required engineering standards to sustain the intended operation over many years.</p><p>Therefore, all construction design must conform to the latest edition of the&nbsp;<a href="https://orf.od.nih.gov/TechnicalResources/Pages/DesignRequirementsManual.aspx">NIH Design Requirements Manual (DRM)</a> and its referenced policies, codes, standards, and technical criteria. For applications submitted to this NOFO, it is expected that each project will implement the best engineering solutions and modern technologies. In situations where animal facilities are proposed, the proposed animal facilities must be compliant with the Required Codes and Standards as specified in Section 1.2.1, including the Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals (<a href="https://olaw.nih.gov/policies-laws/phs-policy.htm">Policy</a>) and Guide for the Care and Use of Laboratory Animals (<a href="https://grants.nih.gov/grants/olaw/guide-for-the-care-and-use-of-laboratory-animals.pdf">Guide</a>).</p><p>Note: There is no maximum for the total cost of a construction project under this NOFO. Each of the two programs, however, allows a different range of the <i>Total Federal Funds Requested</i>. Specifically, the <i>Total Federal Funds Requested</i> allows the range of $2,000,000 to $8,000,000 for applications under the BRF program and $2,000,000 to $4,000,000 for the HRF applications.</p><p>Moreover, the HRF program supports HIV/AIDS-related research that aligned with the NIH OAR priorities, including implementation science for preventing HIV infection, facilities for manufacturing safe HIV interventions/treatments with more effective viral eradication or sustained viral suppression for viruses in their latent reservoirs, or vaccines more potent to suppress viruses with high mutational potential or multiple genetic variants.&nbsp;</p><p>While this NOFO permits a nominal level of supports for fixed equipment listed in Section IV, it is not intended for applications requesting research instruments, replacement of aging or failing equipment, or funding for routine operational needs. Requests for these purposes are not appropriate and will not be supported. Applications for billable medical care, office space, or classrooms are not appropriate in response to this NOFO.</p><p>Applicants may request funds to cover design and implementation costs of the project. Specifically, the allowable costs include the architectural and engineering design fees, contingency fees, construction and fixed equipment expenses, and fees for commissioning of the facility. See the Funding Restrictions section for further details on allowable and non-allowable costs. Applicants are encouraged to follow sustainable design principles and to use green technologies.</p><p>To appropriately conceive, develop, construct, and successfully complete the project, a Program Director/Principal Investigator (PD/PI) should possess knowledge of the relevant scientific field(s) to be served by the proposed facility, demonstrate leadership skills, and assemble a team with technical expertise related to all aspects of the project. The PD/PI does not need to be a currently NIH-funded investigator but is expected to have an appropriate standing in the institutional administration and the research community to lead and oversee the project.</p><p>The project should meet the following criteria and documentation requirements:</p><ul><li>The project must be essential for biomedical research activities supported and the space involved will be used for these activities.</li><li>The facility must be utilized for the biomedical research purposes for which it was constructed or improved for at least 10 years beginning on the date of beneficial occupancy of the space.</li><li>For modernization and renovation projects, the structure must be architecturally and physically suitable for conversion to the type of research space required.</li><li>If the space is rented, evidence must be provided that the terms of the lease and expected subsequent use of the facility are consistent with the proposed project. Specifically, a signed document from the building owner must be provided, detailing that the terms of the lease agreement and subsequent use of the facility will comply with the 10-year term of the Notice of Federal Interest (NFI) requirement following the occupancy of the facility. A statement of agreement by the owner of the space must be included at the time of application submission. These documents will be verified if/when the application is considered for funding.</li><li>If the project affects a site listed (or eligible for inclusion) in the National Register of Historic Places, the requirements specified in "Preservation of Cultural and Historic Resources" must be followed.</li></ul><p>Applicants are strongly encouraged to contact the Scientific/Research Contact listed in Section VII. Agency Contacts to discuss their planned projects before submitting applications. For additional guidance, visit the&nbsp;<a href="https://orip.nih.gov/construction-and-instruments/extramural-construction-programs/c06-program-frequently-asked-questions">C06 Frequently Asked Questions</a> web page.</p>
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<a id='_bookmark259489' tabindex='-1' aria-hidden='true'></a><p>See Section VIII. Other Information for award authorities and regulations.</p>
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<a id='_bookmark259490' tabindex='-1' aria-hidden='true'></a><a name="_Section II. Award Information"></a><h2>Section II. Award Information</h2>
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<a id='_bookmark259491' tabindex='-1' aria-hidden='true'></a>Funding Instrument
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<p>Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.</p>
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<a id='_bookmark259492' tabindex='-1' aria-hidden='true'></a> Application Types Allowed
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<a id='_bookmark259493' tabindex='-1' aria-hidden='true'></a><p>The&nbsp;<a href="http://grants.nih.gov/grants/guide/url_redirect.htm?id=11116"><font color="#0000ff">OER Glossary</font></a>&nbsp;and the SF424 (R&amp;R) Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.</p>
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<a id='_bookmark259494' tabindex='-1' aria-hidden='true'></a>Funds Available and Anticipated Number of Awards
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<p>The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.</p>
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<a id='_bookmark259495' tabindex='-1' aria-hidden='true'></a>Award Budget
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<p>Application budgets are not limited but need to reflect the actual needs of the proposed project.</p><p>The allowed direct cost (Total Federal Funds Requested) is $2,000,000 to $8,000,000 for BRF facilities and $2,000,000 to $4,000,000 for HRF facilities. Applications with a budget less than $2,000,000 will not be considered.</p>
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<a id='_bookmark259496' tabindex='-1' aria-hidden='true'></a>Award Project Period
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<p>The total project period shall not exceed five years. Funds will be provided in a single award with up to a 60-month budget and project period.</p><p>Architectural and engineering design fees are immediately available to applicants at the time of the Notice of Award (NoA); all other award funds are restricted until the Office of Research Infrastructure Programs (ORIP) approves the design documents; upon approval, the NIH will issue a revised NoA to release the restricted award funds.<br>&nbsp;</p>
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<a id='_bookmark259497' tabindex='-1' aria-hidden='true'></a><p>NIH grants policies as described in the <a href="http://grants.nih.gov/grants/guide/url_redirect.htm?id=11120">NIH Grants Policy Statement</a> will apply to the applications submitted and awards made from this NOFO.</p>
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<a id='_bookmark259498' tabindex='-1' aria-hidden='true'></a><a name="_Section III. Eligibility Information"></a><h2>Section III. Eligibility Information</h2>
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<a id='_bookmark259499' tabindex='-1' aria-hidden='true'></a><h4>1. Eligible Applicants</p>
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<a id='_bookmark259500' tabindex='-1' aria-hidden='true'></a>Eligible Organizations
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<p>Higher Education Institutions - Includes all types</p><ul><li>Public/State Controlled Institutions of Higher Education</li><li>Private Institutions of Higher Education</li></ul>
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<a id='_bookmark259501' tabindex='-1' aria-hidden='true'></a><p style="margin-left:0in;">Nonprofits Other Than Institutions of Higher Education</p><ul><li>Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)</li><li>Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)</li></ul>
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<a id='_bookmark259502' tabindex='-1' aria-hidden='true'></a><h4>Foreign Organizations/International Collaborations</h4>
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<a id='_bookmark259503' tabindex='-1' aria-hidden='true'></a><p class="Normal">Non-domestic (non-U.S.) Entities (Foreign Organizations) <strong>are not</strong> eligible to apply.</p>
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<a id='_bookmark259504' tabindex='-1' aria-hidden='true'></a><p>Non-domestic (non-U.S.) components of U.S. Organizations <strong>are not</strong> eligible to apply.</p>
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<a id='_bookmark259505' tabindex='-1' aria-hidden='true'></a><p class="Normal">Foreign components, as <a href="http://grants.nih.gov/grants/guide/url_redirect.htm?id=11118">defined in the NIH Grants Policy Statement</a>, <strong>are not</strong> allowed.</p>
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<a id='_bookmark259506' tabindex='-1' aria-hidden='true'></a>Required Registrations
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<p><strong>Applicant organizations</strong></p>

<p>Applicant organizations must complete and maintain the following registrations as described in the SF 424 (R&amp;R) Application Guide to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted. Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible. Failure to complete registrations in advance of a due date is not a valid reason for late submission, please reference <a href="http://grants.nih.gov/grants/guide/url_redirect.htm?id=82423">NIH Grants Policy Statement 2.3.9.2 Electronically Submitted Applications</a> for additional information.&nbsp;</p>

<ul>
<li><a href="https://grants.nih.gov/grants/guide/url_redirect.htm?id=82390">System for Award Management (SAM)</a> &ndash; Applicants must complete and maintain an active registration, <strong>which requires renewal at least annually</strong>. The renewal process may require as much time as the initial registration. SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code.</li>
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<ul>
<li><a href="http://grants.nih.gov/grants/guide/url_redirect.htm?id=11176">NATO Commercial and Government Entity (NCAGE) Code</a> &ndash; Foreign organizations must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM.</li>
<li>Unique Entity Identifier (UEI)- A UEI is issued as part of the SAM.gov registration process. The same UEI must be used for all registrations, as well as on the grant application.</li>
<li><a href="https://grants.nih.gov/grants/guide/url_redirect.htm?id=11123">eRA Commons</a> - Once the unique organization identifier is established, organizations can register with eRA Commons in tandem with completing their&nbsp;Grants.gov registration; all registrations must be in place by time of submission. eRA Commons requires organizations to identify at least one Signing Official (SO) and at least one Program Director/Principal Investigator (PD/PI) account in order to submit an application.</li>
<li><a href="http://grants.nih.gov/grants/guide/url_redirect.htm?id=82300">Grants.gov</a> &ndash; Applicants must have an active SAM registration in order to complete the Grants.gov registration.</li>
</ul>

<p><strong>Program Directors/Principal Investigators (PD(s)/PI(s))</strong></p>

<p>All PD(s)/PI(s) must have an eRA Commons account. &nbsp;PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons. If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role. Obtaining an eRA Commons account can take up to 2 weeks.</p>
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<a id='_bookmark259507' tabindex='-1' aria-hidden='true'></a>Eligible Individuals (Program Director/Principal Investigator)
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<p>Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed construction as the Program Director/Principal Investigator (PD/PI) is invited to work with their organization to develop an application for support. Multiple PDs/PIs are not allowed.</p>
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<a id='_bookmark259508' tabindex='-1' aria-hidden='true'></a><p style="margin-left:0in;">The PD/PI should hold appropriate stature within the institutional administration structure and research community to be able to oversee various facets of the entire project. The PD/PI should also have a demonstrated record of leadership skills to recruit and guide expert Key Personnel with complementary technical and scientific skills to successfully accomplish the construction project.</p><p style="margin-left:0in;">For the description of roles of Key Personnel, see Senior/Key Person Profile Expanded.</p>
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<a id='_bookmark259509' tabindex='-1' aria-hidden='true'></a><h4>2. Cost Sharing</h4><p>This NOFO does not require cost sharing as defined in the<a href="http://grants.nih.gov/grants/guide/url_redirect.htm?id=11126."> NIH Grants Policy Statement&nbsp;Section 1.2 Definition of Terms</a></p>
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<a id='_bookmark259510' tabindex='-1' aria-hidden='true'></a><h4>3. Additional Information on Eligibility</h4><p><strong>Number of Applications</strong></p>
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<a id='_bookmark259511' tabindex='-1' aria-hidden='true'></a><p>Only one application per institution (identified by NIH IPF number) is allowed.</p>

<p>NIH will not accept duplicate or highly overlapping applications under review at the same time per <a href="http://grants.nih.gov/grants/guide/url_redirect.htm?id=82415">NIH Grants Policy Statement Section 2.3.7.4 Submission of Resubmission Application</a>.&nbsp; This means that the NIH will not accept:</p>

<ul>
<li class="Normal" style="margin: 0in 0in 0.0001pt;">A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission (A1) application.</li>
<li class="Normal" style="margin: 0in 0in 0.0001pt;">A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application.</li>
<li class="Normal" style="margin: 0in 0in 0.0001pt;">An application that has substantial overlap with another application pending appeal of initial peer review (see <a href="http://grants.nih.gov/grants/guide/url_redirect.htm?id=82423">NIH Grants Policy Statement 2.3.9.4 Similar, Essentially Identical, or Identical Applications</a>).</span></li>
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