Cure Quest
Funding Amount
Not stated
Deadline
Deadline not published
Grant Type
Foundation
Overview
Program Overview: Sophia's Fund is committed to supporting research that specifically works toward a cure for childhood cancers and brain tumors. The program funds clinical research initiatives designed to improve treatments and increase survival rates.
Rationale
- Childhood cancer is the leading cause of death by disease in children
- Childhood cancer treatments remain grossly underfunded
- Program aims to support more successful and less harmful treatments
Research Focus
- Rare childhood cancers
- Brain tumors (DIPG - diffuse intrinsic pontine glioma)
- Neuroblastoma (relapsed, refractory, or progressive)
- Innovative combination treatments and personalized immunotherapy
- Molecular-guided therapy
- Cancer vaccine development
- Adoptive T cell therapy
Recent Research Funded
PEACH Protocol - $7,500 contributed
- Prospective treatment for diffuse intrinsic pontine glioma (DIPG) and recurrent neuroblastoma
- Human clinical trial led by pediatric oncology teams at University of Florida and Atrium Health Levine Children's in Charlotte, N.C.
- Tests innovative combination of molecular-guided therapy and personalized immunotherapy
- Uses unique genetic information to design three-pronged approach: tailored drug treatment, cancer vaccine with dendritic cells, and adoptive T cell therapy
DFCI Relapsed, Refractory or Progressive Neuroblastoma - $1,500 contributed
- Dana Farber Cancer Institute & Jimmy Fund
- Phase 2 Randomized Study of Irinotecan/Temozolomide/Dinutuximab with or without Eflornithine (DFMO)
- IND# 141913
- Research on children with relapsed, refractory or progressive neuroblastoma
What Sophia's Fund Inc actually gave
Source: IRS Form 990-PF, 2021 — the most recent filing with itemized grants
- Grants in 2021
- 7
- Total given
- $11K
- Median grant
- $1,000
- Range
- $50–$4,800
- By dollars: New Hampshire 42%, Massachusetts 27%, North Carolina 22%. Top recipient cities: Bedford, NH; Charlotte, NC; Boston, MA.
- 0% of grants with a stated purpose were for general or operating support.
Example grants
Childhood Cancer Lifeline · Bedford, NH
Assist children in treatment
$4,800
Atrium Health Foundation · Charlotte, NC
Peach protocol
$2,500
Dana Farber · Boston, MA
Cancer research
$2,500
Yansen Perez · Worcester, MA
Financial assistance
$500
Coalition Against Childhood Cancer · Philadelphia, PA
Assist children and families in treatment
$100
Focus Areas & Funding Uses
Fields of Work
- Cancer
- Science research
Categories
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Deadline
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Based on past cycles
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