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Clinical Trials To Advance Therapies For Cardiovascular Disease In Type 1 Diabetes Grant

Breakthrough T1D

Funding Amount

Up to US $3,000,000

Deadline

Deadline not published

Grant Type

Foundation

Can we apply?

Check your organization against each line. Taken from the listing; confirm with the funder's guidelines.

Required status

  • 501(c)(3) tax-exempt status

Overview

Breakthrough T1D is dedicated to improving cardiovascular outcomes for individuals with type 1 diabetes (T1D). This funding opportunity aims to support clinical trials that evaluate innovative therapies for cardiovascular disease (CVD) in T1D patients. Grants of up to $3 million will be awarded over three years to encourage research that addresses the unmet needs of this population, enhancing both treatment options and care access.

Breakthrough T1D
Founded in 1970 by families whose loved ones had been diagnosed with type 1 diabetes (T1D), Breakthrough T1D is a tax-exempt nonprofit 501(c)3 organization.
We lead the way to more effective solutions by connecting the brightest minds to advance treatments, influence policy, and improve access to care.​ By driving innovation forward, Breakthrough T1D will make type 1 diabetes a condition of the past.
Clinical trials to advance therapies for cardiovascular disease in type 1 diabetes
Summary
The goal of this funding opportunity is to advance therapies to improve cardiovascular outcomes in people with established type 1 diabetes (T1D).This funding opportunity will prioritize clinical trials evaluating promising therapies, whether repositioned, repurposed, in development, or already approved, for cardiovascular disease (CVD) in people with T1D.This initiative will award grants for clinical studies to academic investigators and industry partners of up to $3,000,000.00 over 3 years.
Funding Opportunity Description
Breakthrough T1D is committed to the development of therapies to improve clinical outcomes in people with type 1 diabetes (T1D). Cardiovascular disease (CVD) is the primary cause of morbidity and mortality in people with T1D. There is currently a lack of targeted therapies for CVD approved for use by people with T1D, in part because people with T1D are seldom included in drug trials for these diabetic complications. To fill this gap, Breakthrough T1D invites applications for clinical trials to advance therapies to improve CVD outcomes in T1D.

What Breakthrough T1D actually gave

Source: IRS Form 990, 2025

Grants in 2025
100
Total given
$79.32M
Median grant
$378K
Range
$25K–$7.28M
  • By dollars: Massachusetts 21%, California 13%, Florida 7%. Top recipient cities: Boston, MA; New York, NY; Seattle, WA.
  • 0% of grants with a stated purpose were for general or operating support.
  • 16% of recipients were new grantees, not repeat recipients.

Example grants

  • University of Massachusetts Medical School · Worcester, MA

    T1d research

    $7.28M

  • The Regents of the University of California San Francisco · San Francisco, CA

    T1d research

    $5.4M

  • The University of Chicago · Chicago, IL

    T1d research

    $4.12M

  • Regents of the University of Colorado · Denver, CO

    T1d research

    $3.58M

  • University of Florida · Gainesville, FL

    T1d research

    $3.13M

IRS Form 990, 2025. Amounts as reported by the funder. Full 990 history →

Focus Areas & Funding Uses

Fields of Work

  • Science research
  • Healthcare

Categories

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