National Institutes of Health logo

Trailblazer Award for New and Early Stage Investigators (R21 Clinical Trial Optional)

National Institutes of Health

Funding Amount

Varies

Deadline

May 7, 2026

29 days left

Grant Type

federal

Overview

Trailblazer Award for New and Early Stage Investigators (R21 Clinical Trial Optional)

This Trailblazer Award is an opportunity for NIH-defined New and Early Stage Investigators (https://grants.nih.gov/policy/early-investigators/index.htm) to pursue research programs that integrate engineering and the physical sciences with the life and/or biomedical sciences. A Trailblazer project may be exploratory, developmental, proof of concept, or high risk-high impact, and may be technology design-directed, discovery-driven, or hypothesis-driven. Importantly, applicants must propose research approaches for which there are minimal or no preliminary data.A distinct feature for this FOA is that no preliminary data are required, expected, or encouraged. However, if available, minimal preliminary data are allowed. Preliminary data are defined as material which the applicant has independently produced and not yet published in a peer-reviewed journal. All preliminary data should be clearly marked and limited to one-half page, which may include one figure. Applications including data more than one-half page or more than one figure will be considered noncompliant with the FOA instructions and will not go forward to review.

Details

  • Agency: National Institutes of Health
  • Department: Department of Health and Human Services
  • Opportunity #: PA-25-169
  • Instrument: grant

Eligibility

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Eligibility

Eligible Applicant Types

private_institutions_of_higher_educationfor_profit_organizations_other_than_small_businessesfederally_recognized_native_american_tribal_governmentsspecial_district_governmentsother_native_american_tribal_organizationssmall_businessespublic_and_state_institutions_of_higher_educationothernonprofits_non_higher_education_with_501c3nonprofits_non_higher_education_without_501c3county_governmentscity_or_township_governmentsindependent_school_districtspublic_and_indian_housing_authoritiesstate_governments

How to Apply

PA-25-169 Full Announcement Text

<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd">
<html xmlns="http://www.w3.org/1999/xhtml">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
<meta http-equiv="refresh" content="0; URL='http://grants.nih.gov/grants/guide/pa-files/PA-25-169.html'" />
<title>PA-25-169</title>
</head>
<body>
</body>
</html>

Focus Areas & Funding Uses

Fields of Work

science-research

Categories

Browse similar grants by category

Related Grants

Similar grants from this funder and related organizations

Ready to apply for Trailblazer Award for New and Early Stage Investigators (R21 Clinical Trial Optional)?

Grantable helps you assess fit, draft narratives, and track deadlines — so you can submit stronger applications, faster.