National Center for Construction Safety and Health Research and Translation (U54)

NIOSH RFA-OH-24-001

RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
Department of Health and Human Services
Part 1. Overview Information
Participating Organization(s)
Centers for Disease Control and Prevention (CDC)
The policies, guidelines, terms, and conditions of the HHS Centers for Disease Control and
Prevention (CDC) stated in this notice of funding opportunity (NOFO) might differ from those
used by the HHS National Institutes of Health (NIH). If written guidance for completing this
application is not available on the CDC website, then CDC will direct applicants elsewhere for
that information.
Components of Participating Organizations
National Institute for Occupational Safety and Health (NIOSH)
Funding Opportunity Title
National Center for Construction Safety and Health Research and
Translation (U54)
Activity Code
U54 Specialized Center- Cooperative Agreements
Announcement Type
Reissue of RFA-OH-19-001
Related Notices
None
Notice of Funding Opportunity (NOFO) Number
RFA-OH-24-001
Companion Notice of Funding Opportunity
None
Number of Applications
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
Only one application per institution is allowed, as defined in Section III. 3. Additional
Information on Eligibility.
Assistance Listing Number(s)
93.262
Funding Opportunity Purpose
NIOSH is seeking applications from qualified organizations for a National Center for
Construction Safety and Health Research and Translation (also known as the NIOSH National
Construction Center). Applicants are expected to propose multi-disciplinary approaches for
impactful applied and intervention research and hazard identification and controls, to develop
partnerships for implementing prevention and intervention activities, and to serve as leaders in
research translation and research-to-practice for the protection of construction workers in the
United States. The NIOSH National Construction Center will accomplish these goals by 1)
integrating and advancing research, 2) translating and disseminating best practices, 3)
disseminating information, 4) informing policy, and 5) building capacity. Applicants must
describe the occupational health and safety burden(s) addressed in their proposals. In
addition, they must link the need for the proposed research and related activities to the
planned outputs and outcomes that will help address or alleviate the construction sector
burdens described. Applicants should also describe the anticipated impacts and potential
outcomes of the proposed research and related activities that will occur during the 5-year
project period and beyond.
Key Dates
Posted Date
August 28, 2023
Open Date (Earliest Submission Date)
November 1, 2023
Letter of Intent Due Date(s)
The first Letter of Intent due date is November 1, 2023. Thereafter, 30 days prior to the
application due date
Application Due Date(s)
December 1, 2023; October 31, 2024; October 31, 2025; October 30, 2026
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
On-time submission requires that electronic applications be error-free and made available to
CDC for processing from the NIH eRA system on or before the deadline date. Applications
must be submitted no later than 11:59 PM U.S. Eastern Time on the listed application due
date.
Applicants will use a system or platform to submit their applications through Grants.gov and
eRA Commons to CDC. ASSIST and an institutional system to system (S2S) solution are
options. ASSIST is a commonly used platform because it provides a validation of all
requirements prior to submission and prevents errors.
For more information on accessing or using ASSIST, you can refer to the ASSIST Online Help
Site at: https://era.nih.gov/erahelp/assist . Additional support is available from the NIH eRA
Service Desk via https://www.era.nih.gov/need-help.
· E-mail: commons@od.nih.gov
· Phone: 301-402-7469 or (toll-free) 1-866-504-9552
· Hours: Monday - Friday, 7 a.m. to 8 p.m. Eastern Time, excluding Federal holidays.
Applicants are encouraged to apply early to allow adequate time to make any corrections to
errors found in the application during the submission process by the due date.
Note: HHS/CDC grant submission procedures do not provide a period beyond the application
due date time to correct any error or warning notices of noncompliance with application
instructions that are identified by Grants.gov or eRA systems (i.e., error correction window).
AIDS Application Due Date(s)
Not Applicable
Scientific Merit Review
May 2024; March 2025; March 2026; March 2027
Advisory Council Review
June 2024; April 2025; April 2026; April 2027
Earliest Start Date
September 1, 2024
Expiration Date
December 1, 2026
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
Due Dates for E.O. 12372
Not Applicable
Required Application Instructions
It is critical that applicants follow the Multi-Project (M) Instructions in the SF424 (R&R)
Application Guide, except where instructed to do otherwise in this NOFO. Conformance to all
requirements (both in the Application Guide and the NOFO) is required and strictly enforced.
Applicants must read and follow all application instructions in the Application Guide as well as
any program-specific instructions noted in Section IV. When the program-specific
instructions deviate from those in the Application Guide, follow the program-specific
instructions. Applications that do not comply with these instructions may be delayed or
not accepted for review.
Telecommunications for the Hearing-Impaired: TTY 1-888-232-6348.
There are several options available to submit your application through Grants.gov to NIH and Department of Health
and Human Services partners. You must use one of these submission options to access the application forms for
this opportunity.
1. Use the NIH ASSIST system to prepare, submit and track your application online.
2. Use an institutional system-to-system (S2S) solution to prepare and submit your application to Grants.gov
and eRA Commons to track your application. Check with your institutional officials regarding availability.
Table of Contents
Part 1. Overview Information
Part 2. Full Text of the Announcement
Section I. Notice of Funding Opportunity Description
Section II. Award Information
Section III. Eligibility Information
Section IV. Application and Submission Information
Section V. Application Review Information
Section VI. Award Administration Information
Section VII. Agency Contacts
Section VIII. Other Information
Part 2. Full Text of Announcement
Section I. Notice of Funding Opportunity Description
Statutory Authority
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
This program is described in the Assistance Listings and is not subject to the
intergovernmental review requirements of Executive Order 12372 or Health Systems
Agency Review. Awards are made under the authorization of the Occupational Safety and
Health Act of 1970, Section 20(a) and 21(a) (29 USC 669(a) and 29 USC 670); Federal
Mine Safety and Health Act, Section 501(a), 30 USC 1 (Note), and 30 USC 951(a); and
Section 301 of the Public Health Service Act as amended (42 USC 241) and under
Federal Regulations 42 CFR Part 52. All awards are subject to 45 CFR Part 75, the terms
and conditions, cost principles, and other considerations described in the HHS Grants
Policy Statement.
Background and Purpose
Every day, millions of U.S. workers go to work with the expectation of returning home
healthy and safe. However, the workplace environment can significantly impact a worker's
physical and psychological health. Depending on the nature of the job, workers may be at
risk for various types of injuries, illnesses, or even death. Work-related illnesses are often
underestimated because it can be challenging to recognize or associate them with past
occupational exposures.
According to the U.S. Bureau of Labor Statistics (BLS), in 2021, private industry
employers reported approximately 2.6 million nonfatal workplace injuries and illnesses,
based on the Survey of Occupational Injuries and Illnesses (SOII) data. The BLS Census
of Fatal Occupational Injuries (CFOI) reports 5,109 fatal work injuries in 2021 in the United
States. Work-related injuries, illnesses, and deaths are costly to American society. In
2020, employers spent $93 billion on workers' compensation, as reported by the National
Academy of Social Insurance.
BLS estimates indicate that in 2021, there were 2.5 nonfatal workplace injuries per 100
full-time construction workers. Additionally, construction and extraction occupations had
951 fatal injuries in 2021, accounting for 19% of the nation's total work-related deaths.
Most of these deaths are preventable. Falls and struck-by incidents are the leading
causes of fatalities in construction, with falls accounting for about 39% of work-related
deaths in construction followed by struck-by incidents. Specifically, in 2021, 370 out of 951
total construction fatalities were due to falls. Within the construction industry groups at
higher risk for different health outcomes have been identified – where possible, it is
important to increase efforts to focus prevention efforts where impact may be greatest. For
example, among construction workers roofers had the highest rate of fatal injuries, 59 per
100,000 FTE, in 2020. Beyond physical health risks, current issues related to mental
health (including suicide) and substance use disorder (including opioid use disorder) are
having a major impact among construction workers and workplaces. The construction
industry has one of the highest suicide rates compared to other industries, with suicide
rates rising dramatically in recent years. According to the Centers for Disease Control and
Prevention (CDC), there were more than 80,000 opioid-related overdose deaths in 2021 -
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
a 15% increase from the previous year. Construction workers are at greater risk for
overdose and at greater risk of dying from opioid-related overdoses than the average
worker.
NIOSH is an agency operating within the CDC. The mission of NIOSH is to generate new
knowledge in the field of occupational safety and health and transfer that knowledge into
practice to prevent worker injury, illness, and death. To accomplish this mission, NIOSH
conducts and funds scientific research, develops methods to prevent occupational
hazards, develops guidance and authoritative recommendations, translates scientific
knowledge into products and services, disseminates information, identifies factors
underlying work-related disease and injury, and responds to requests for workplace health
hazard evaluations.
NIOSH organizes its research program under the framework of the National Occupational
Research Agenda (NORA). NORA is a partnership program to stimulate innovative
research and improved workplace practices. Unveiled in 1996, NORA began its third
decade (2017–2026) with an enhanced structure. It now consists of ten industry sectors
based on major areas of the U.S. economy, and seven health and safety cross-sectors
organized according to the major health and safety issues affecting the U.S. working
population.
This funding opportunity provides support for a National Center for Construction Safety
and Health Research and Translation (National Construction Center) to address the
significant and varied burden of work-related injuries and illnesses in the U.S. construction
industry. The NIOSH National Construction Center serves as a national leader in
construction research, implementation, and dissemination of scientific discoveries to
benefit construction workers by working to prevent or reduce work-related injuries and
illnesses. The NIOSH National Construction Center recipient will address both regional
and national construction worker safety and health issues and prioritize the creation,
dissemination, and widespread use of evidence-based solutions to address the most
critical safety and health problems in the construction industry. Furthermore, the NIOSH
National Construction Center will establish a publicly accessible online repository for
research data, indicators, and research-to-practice materials and products. The
overarching goal of the National Construction Center is to reduce adverse construction
worker health and safety outcomes by studying, developing, and implementing evidence-
based practices and solutions.
Healthy People 2030 and other National Strategic Priorities
The United States Public Health Service (PHS) is committed to achieving a society in
which all people live long, healthy lives. The vision, mission, and goals are found in
Healthy People 2030, a PHS-led national activity to achieve better health in the United
States by the year 2030. This funding announcement is linked to the goals of Healthy
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
People 2030, which are intended to prevent work-related diseases, injuries, and deaths
while improving worker health, safety, and well-being.
According to Healthy People 2030, more than 160 million people participate in the U.S.
labor force, and their work has an intrinsic connection to their safety and health. Decades
of public health surveillance and research have demonstrated that work-related injuries
adversely affect employers, workers, and communities. Workplace settings vary widely in
size, sector, design, location, processes, culture, and resources. In addition, workers
themselves have different ages, genders, education levels, cultural backgrounds, health
practices, vulnerabilities, and levels of access to preventive health care. This translates
into great diversity and disparity in the safety and health risks for each industry sector and
the need for tailored interventions.
The Healthy People 2030 occupational safety and health objectives aim to prevent illness,
injury, and disease due to working conditions. All objectives, core and developmental,
align with NIOSH’s strategic plan and are addressed through NORA, a program
established by NIOSH that works with partners from academia, industry, labor, and
government to stimulate research and improve workplace practices.
Public Health Impact
NIOSH programs support research and related activities that address worker safety, injury
prevention, and health concerns across a wide spectrum of industries and occupations.
NIOSH also supports approaches that include basic research through implementation
research, which takes research knowledge and promotes implementation and use through
development and application of engineering controls, new technologies, and
communication products. Through this announcement, NIOSH is seeking meritorious
applications for a National Construction Center that will assist NIOSH and NIOSH
construction program leadership in reducing and preventing occupational injury, illness,
death, and disability among U.S. construction workers.
Relevant Work
For over three decades, NIOSH has funded extramural research covering a diverse range
of topics and approaches related to construction safety and health. Through a series of
cooperative agreements, the NIOSH-sponsored National Construction Center has played
a key role in conducting and synthesizing research, implementation, policy, training, and
education. NIOSH has successfully supported the advancement of new knowledge in the
field of occupational safety and health and its transfer into practice, with the ultimate goal
of reducing the burden of occupational injuries, illnesses, and fatalities. More information
can be found at the NIOSH Office of Extramural Programs and the NIOSH Construction
Research Program.
Approach
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
Applications for this funding opportunity should have a national scope for research,
implementation, dissemination, and related activities described in this announcement. The
proposed projects should aim to achieve the following objectives: 1) reducing and
preventing construction worker exposures to safety and health hazards, 2) improving the
safety culture and safety climate within the construction industry, 3) applying prevention
through design, the hierarchy of controls, and emerging technologies where appropriate to
address industry hazards, and 4) widely disseminating best practices and other
information for use by workers, employers, contractors, and site owners. The National
Construction Center is expected to work closely with NIOSH construction program
leadership, academic and research partners, and other organizations to advance research
integration and inform best practices and effective worksite solutions in the U.S.
construction industry. Applicants should clearly describe how the intended outcomes of
the proposed work will contribute to the specified goals in NIOSH's Strategic Plan and, in
the NIOSH Priority Goals for Extramural Research.
National Construction Center Structure
The NIOSH National Construction Center provides interdisciplinary research and outreach
efforts to address occupational health and safety hazards in construction. Applicants
should consider the required and optional components essential to the National
Construction Center function, detailed below, in providing an overall description of the
proposed Center, addressing 1) the burden of occupational injuries and illnesses for the
construction sector, 2) the national need for the Center’s proposed programs and projects,
and 3) the Center’s impact, or potential for impact, on construction worker health and
safety.
To effectively address the purpose and scope of this NOFO, the following required
components will enable the Center to cohesively address established goals and
objectives for providing impact:
Planning, Administration, and Evaluation Core
Construction Industry Data and Statistical Core
Communication, Outreach, and Education Core
Research-to-Practice Core
Applied Research Projects (collectively, the Applied Research Core)
Planning, Administration, and Evaluation Core (up to 20% of total costs/year). The
purpose of this core is to 1) provide oversight, leadership, and management for the
Center, including establishment and maintenance of advisory committees; 2) engage in
long-range planning, coordination, and implementation of work that crosses multiple
cores, programs or projects; and 3) develop and assist in implementing evaluation efforts
at the Center, core, program and project levels.
Construction Industry Data and Statistical Core (up to 10% of total costs/year). This core
acquires, analyzes, interprets and disseminates data, indicators, and important
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
changes/trends within and impacting the construction sector. The types of data can
include construction related injury, illness, disability, deaths, industry characteristics,
advances in methods, equipment, or technologies, as well as indicators such as
employment and demographic economic variables.
Communication, Outreach, and Education Core (up to 10% of total costs). The purpose
of this core is to ensure that evidence-based approaches, technologies, guidelines,
policies, best practices, or similar activities that are known to be effective are promoted
and disseminated to benefit workers and their associated work environments. This core
develops partnerships with a diverse group of stakeholders to help ensure that research
outputs, outcomes, and impacts can be disseminated widely. A variety of pathways should
be used, such as live meetings, webinars, websites, and social media.
Research-to-Practice Core (up to 30% of total costs/year). This core ensures a
systematic approach focused on the use, adoption, and adaptation of interventions and
technologies that translate research findings into practice to reduce and eliminate
occupational injuries, illnesses, and fatalities in the construction sector. The purpose of
this core is to bridge the gap between research and practice by effectively integrating
knowledge, interventions, and technologies into workplace policies, procedures, and
practices.
Applied Research Core (up to 30% of total costs/year). This core consists of a variety of
individual research projects that address burden, need, and impact to improve
occupational safety and health in the construction sector. Applied research builds the
evidence base for effective prevention and intervention practices.
Guidance has been provided for the approximate budget allocation expected for each
core. Applicants may request, with justification, more or less funding for any of the cores,
provided they do not exceed the total costs allowed under this NOFO.
Applicants are encouraged to propose a pilot studies subprogram as part of the Planning,
Administration, and Evaluation Core or the Research-to-Practice Core. Provide a clear
description of the program within the appropriate core and fully justify the requested
budget. All laws and regulations related to federal funding will apply. NIOSH will neither
peer-review individual pilot project proposals nor make available an institutional review
board for that purpose.
Research Project Categories
The types of research projects that are strongly recommended within the Applied
Research and Research to Practice Cores are described below.
Applied Research builds the evidence base upon which future programs, policies, and
progress are supported. Examples of research falling within this category include
epidemiological studies, laboratory studies combined with field studies, and other projects
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
that work to reveal disease and injury causation or exacerbation. NIOSH encourages
applicants to propose rigorous study designs, such as longitudinal studies, adequately
powered study designs, studies involving comparison populations, the use of objective
measures, and state-of-the-art data analysis techniques. Results from this type of
research are most frequently disseminated via publications, conference presentations,
and trade journals/bulletins. Generally, proposals of laboratory-only basic research will not
be considered unless there is a compelling rationale, such as studying a new or emerging
problem/exposure in the construction sector.
Intervention Research engages in the development, testing, or evaluation of biomedical,
human factors, and/or behavioral solutions to an occupational safety and health problem
or the improvement of an existing intervention. Intervention research may include the
development of a new training program, testing of new technologies or approaches, or the
evaluation of new workplace policies, procedures, or tailored programs. Intervention
research is differentiated from implementation research through the performance of
research or field tests to develop interventional strategies, whereas implementation
research develops channels and/or partnerships to disseminate these strategies.
The proposed NIOSH National Construction Center is expected to identify the kinds of
construction sector research questions and intervention research questions that can be
accomplished through partnerships, collaborations, networks, and consortia. It should take
full advantage of the scientific expertise and infrastructure offered by specialized programs
and partners. Access to construction worker populations or jobsites is paramount and
should be clearly described.
Implementation Research (previously referred to as Translation Research): These
projects study the processes by which interventions that were developed and tested to
address occupational safety and health (OSH) hazards and risks and/or promote health
and well-being (i.e., under the intervention research umbrella) are disseminated, adopted,
implemented, sustained, and scaled up equitably in real-world settings. Research under
this area will use models, methods, and measures to systematically identify, develop,
evaluate, and refine strategies that support the dissemination, adoption, implementation,
sustained use, and scale up of previously tested interventions into community and
workplace settings for all workers and especially those who are disproportionately
impacted by OSH risks and hazards.
In the context of implementation research, strategies are defined as a set of activities
(often multicomponent) that support the dissemination, adoption, implementation,
sustainment, and scale up of tested interventions. Implementation research answers the
ultimate question of what strategies work for whom under what circumstances to support
the dissemination, adoption, implementation, sustainment, and scale up of tested
interventions.
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
The proposed National Construction Center is expected to overcome technical and/or
communication 'bottleneck' issues through collaborations and leverage external
specialized programs and partners to advance implementation effectiveness.
Scientific/academic collaboration is crucial for achieving intended outputs and outcomes.
Surveillance Research guides efforts to detect and monitor disease, injuries, and
disabilities and to assess the impact of interventions. Surveillance information can inform
policy changes, new program interventions, public communications, and priorities for
research investment. Surveillance research may involve the identification and melding of
disparate, available data sources to generate reliable morbidity and mortality estimates or
the development of unique surveillance methods for specific trades, business sizes,
hazards, or adverse health outcomes. Analyses of available surveillance data are not
considered research in this context.
The National Construction Center is strongly encouraged to leverage financial and
technical resources/systems for the design and operation of a construction sector
surveillance system. The Center is expected to identify the types of construction research
questions that can be accomplished through formal data access or sharing agreements,
collaborations, networks, and consortia. Specialized consulting/expertise may be
warranted for computing and data management infrastructure, data set linking,
longitudinal and other types of analyses, website data depiction and access, among other
areas. One output of this activity should be a publicly accessible yearly update of
statistical data, such as an electronic injury and illness chart book.
For all of the above categories, the National Construction Center should have appropriate
policies and procedures to ensure scientific integrity and responsible conduct and
protections for federally sponsored research.
Note: Federally sponsored data access and open access publication policies will apply.
Strategic Goals
The NIOSH Strategic Plan for FY2019-2026 identifies strategic and intermediate goals for
the NIOSH research portfolio. The strategic goals listed below represent the major health
and safety issues facing the U.S. workforce and are the broad focus areas for this funding
opportunity. The NIOSH Construction Program has highlighted components of the NIOSH
Strategic Plan for the purposes of prioritizing work within NIOSH - the priority areas are:
Preventing harmful noise exposure
Reducing occupational musculoskeletal disorders
Reducing occupational respiratory diseases
Improving workplace safety to reduce traumatic injuries from events such as falls from elevation and
struck-by incidents
Promoting safe and healthy workplaces, including use of Total Worker Health® approaches, to address
adverse mental health outcomes and issues related to harmful substance use.
The NIOSH Construction Program has, through work of the NORA Construction Sector
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
Council, identified 16 priority areas and emerging issues currently most relevant to the
construction workforce in the U.S. Those priorities and emerging areas are published in
the National Occupational Research Agenda for Construction.
Intermediate Goals
NIOSH has identified intermediate goals defined as specific actions needed to be taken in
order to achieve or advance the strategic goals. In some cases, NIOSH has also identified
areas where extramural research is needed to fill a gap or provide a capacity that NIOSH
alone cannot fill. Extramural priority research goals have been identified as areas where
work in the extramural community is sought. Priority will be given to projects that address
the extramural research goals. A full description of the strategic and intermediate goals is
available on the NIOSH Strategic Plan website. See the Extramural Priority Research
Goals for more information on extramural priorities.
Applicants: Review the following websites for updates about NIOSH strategic and
intermediate goals, research goal priorities, and other current information as you craft and
submit your research proposals:
National Occupational Research Agenda (NORA) - https://www.cdc.gov/nora/
NIOSH Programs - https://www.cdc.gov/niosh/programs/
NIOSH Office of Extramural Programs - https://www.cdc.gov/niosh/oep
NIOSH Priority Goals for Extramural Research - https://www.cdc.gov/niosh/programs
/prioritygoals.html
NIOSH Construction Program Evaluation Review report -
https://www.cdc.gov/niosh/programs/review/default.html
Burden, Need and Impact
The Center should address the burden, need, and potential impact of work-related injury
and illness in the construction sector through a comprehensive and integrated approach to
research, dissemination and implementation of evidence-based knowledge, interventions,
and practices. The third decade of NORA encompasses a new framework for assessing
research priorities and aligning NIOSH research investments. This burden-need-impact
framework is known by its acronym, BNI. Research funded under this announcement will
advance the strategic and intermediate goals of the NIOSH Strategic Plan based on BNI.
More information on the BNI Framework is available at the NIOSH website.
Burden. Burden is risk from any of the following: exposure to hazards; occurrence of
injuries, illnesses, or deaths due to work-related factors; and impacts on economic factors
and well-being. The extent of exposure can be in terms of the number of workers
exposed, the magnitude of the exposure, or both. The assessment of burden is based on
several main constructs: magnitude of the problem; health impact severity; exposure to
workers; societal costs; new or emerging issues; and relationship to the work
environment. The assessment of burden should consider whether there are disparities in
workers’ exposures and should examine social determinants of health which may be
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
responsible for inequities in workers’ exposures. For emerging issues, the burden is
anticipatory.
Need. Although burden is a foundational factor in setting priorities, need is also a critical
factor. NIOSH should not only invest in an important burden area but also focus time and
resources on the most relevant and impactful issues pertaining to the burden. The need
for research also includes whether social determinants of health among the study
population have been considered.
Impact. The assessment of impact is based on the potential for the activity to be
successful in generating knowledge or products that will be used by NIOSH partners
(intermediate outcomes). Researchers should describe how these intermediate outcomes
might result in reduced burden or improved health, safety, and well-being of workers in the
near-or long-term. An important component of impact addresses whether, and how, the
benefits of the research are to be equitably distributed to all affected worker group.
Objectives/Outcomes
Center Goals and Objectives
Clearly state proposed goals and objectives of the National Construction Center in the
application and directly link them to the health and safety burdens in construction being
addressed. Justify the proposal by describing the burden of the problem, the need for the
proposed research or activity, and the potential for impact or likelihood of successful
results. Objectives should support the strategic and intermediate goals NIOSH has
established.
Applicants may propose other topics, provided you describe a clear, compelling scientific
rationale including stakeholder needs; target audience information for research and/or
dissemination, and implementation; anticipated outputs and outcomes; and how and for
whom the research will advance the scientific body of knowledge, policy, and/or practices.
These topics may be proposed in the form of a research project proposal (for example,
robotic–worker integration risk factors for occupational safety and health). NIOSH will not
accept or fund surveillance-only or training-only proposals.
State which NIOSH construction strategic and intermediate goals are addressed for each
core and individual research project and provide a rationale for how the proposed
research will contribute to the specified priority area(s). Put this information in both the
Description/Abstract and the Research Strategy (Significance) sections for each core and
project of the application. For research projects, the proposal should identify the NIOSH
strategic and intermediate goals your work will address.
Explain how the proposed activities and research will contribute to the NIOSH Research to
Practice effort for construction and state the expected outputs and outcomes.
Target Population
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
The ultimate beneficiaries of this cooperative agreement are all construction workers in
the United States. The construction industry is a high hazard industry, and all construction
workers are important. Some worker groups have overlapping vulnerabilities that increase
risks for adverse health outcomes even further. These include (but are not limited to)
young, Hispanic immigrant workers who are employed by small construction businesses.
Which population(s) of workers will you address in your research? Clearly identify them,
either specifically or more broadly (for example, tradespeople, laborers, foremen, or
professionals). See the National Occupational Research Agenda for Construction
document for a discussion of target audiences.
Diversity, Equity, and Inclusion
In June 2019, NIOSH began an initiative to take substantive action in creating greater
diversity, equity, and inclusion in its workforce, the workplace and in its service to the
public. This initiative led to the establishment of the NIOSH Diversity, Equity, and Inclusion
Office. The associated strategic plan is intended to guide actions that specifically address
diversity, equity, inclusion, and accessibility (DEIA) in all aspects of NIOSH's work,
including NIOSH-supported extramural programs. Applicants should demonstrate a
commitment to DEIA in all aspects of their proposed Center (including partnerships,
outputs, and outcomes) in the Research Strategy section of the application.
Asymmetrical power relationships along social axes such as age, class, gender, nativity,
and race/ethnicity not only result in social, economic, and environmental disadvantages
that impact the distribution of work-related benefits and risks, but also result in
exclusionary research practices.
Developing inclusive research and dissemination practices, and the institutional capacity
to effectively advance data equity and produce data driven solutions that reduce avoidable
disparities and inequities, is essential to ensuring the well-being of the increasingly diverse
workforce. Applicants should identify how the Center will ensure that research questions,
data collection methods and analysis, and dissemination of results will be inclusive of the
diversity in the construction sector workforce, especially those from groups that have
historically been underrepresented. Applicants should also demonstrate how the design,
content, format, and dissemination of outreach efforts will be tailored to the needs of
workers from diverse backgrounds.
Collaboration/Partnerships
Interdisciplinary and multidisciplinary collaborations that share expertise are essential to
advancing occupational safety and health. Partnerships are also critical to translate
research findings into effective work practices, and these are encouraged by the NIOSH
Research to Practice program (see below). Applicants are expected to propose relevant
collaborations and/or partnerships that will strengthen the proposed work and seek to
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
address a wide range of occupational safety and health concerns, as determined by the
burdens posed by these hazards and are encouraged to describe how their efforts will
alleviate or eliminate these burdens.
Evaluation/Performance Measurement
Evaluations provide information for management and improve program effectiveness.
Information concerning Evaluation of NIOSH Programs may be helpful. Effective program
evaluation is a systematic way to improve and account for public health actions by
involving procedures that are useful, feasible, ethical, and accurate. Understanding and
applying the elements of a framework for evaluation of research projects may enhance the
planning of effective public health strategies, the improvement of existing programs
(including evidence-based activities), and the demonstration of beneficial results and
impact of federal funding.
Ongoing evaluation of NIOSH National Construction Center activities as well as specific
research and outreach projects or programs is expected and should be managed and
coordinated by the Planning, Administration, and Evaluation Core. Submission of annual
NIOSH Program Performance One-page summaries is expected. The Center is also
strongly encouraged to interact with NIOSH and other partners to increase awareness of
projects and evaluation techniques across partners and stakeholder groups. In addition to
center-specific evaluation and performance measurement, the collaboration Center may
be asked to contribute to periodic NIOSH program reviews.
Translation Plan
The NIOSH National Construction Center is expected to develop and implement a
translation plan to move effective solutions into the workplace. The Center should use and
leverage resources of NIOSH and other partners wherever feasible to strengthen and
prevent duplication of effort.
Data Resources
NIOSH data resources are available to researchers at the NIOSH Data and Statistics
Gateway. This includes Worker Health Charts that NIOSH creates from data it gathers
from the BLS. These specialized charts assess the rates, distribution, and trends in
workplace injuries, illnesses, and deaths. The data can be used to help provide the
context and estimate the burden of the problems being addressed, the need for the
proposed work, the impact on the workforce, and the potential long-term benefits of the
proposed projects and activities. Additionally, issues can be contextualized through
economic metrics including societal cost, medical cost, productivity losses, and disability
costs.
Research-to-Practice
NIOSH has established a Research to Practice (r2p) approach to reduce or eliminate
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
occupational illness and injury by increasing the transfer and implementation of
knowledge, interventions, and technologies into highly effective prevention practices and
products into the workplace. Through r2p, NIOSH collaborates with partners on the use,
adoption, and adaptation of NIOSH knowledge, interventions, and technologies that will
move research into practice in order to reduce and eliminate injuries, illnesses, and
fatalities. The r2p approach is an interactive process in which the occupational safety and
health community—including researchers, communicators, decision-makers, and
employer/employee groups—works collaboratively to
Identify research needs
Design, plan, and conduct studies
Translate and disseminate existing knowledge, interventions, and technologies to relevant users for
implementation in the workplace.
Evaluate results to determine the impact on occupational safety and health.
Note to Applicants:
Applicants are expected to state how the proposed research addresses r2p, in both the
Description (Abstract) and the Research Strategy (Significance) in Section IV. For
example, describe the anticipated strategies for implementation and/or dissemination of
research findings, including by audience segmentation and by the characteristics of the
channels or modes of dissemination.
Outputs and Outcomes
Governmental agencies and organizations have been faced with increasing demand to
measure the effectiveness of their funded research in improving public health. The
products (outputs) of research activities and subsequent outcomes—that is, benefits or
changes at an individual or population level—can measure effectiveness. Outputs are the
immediate products or direct result of research or other occupational health activities.
Examples include publications, reports, conference proceedings, presentations/posters,
investigator career development, databases, tools, methods, guidelines, and
recommendations.
The causes of work-related injuries and illnesses are complex and determining the effect
that specific research activities have on them can take years. Thus, outcomes can be
measured over time as either short-term, intermediate, or end outcomes.
Short-term outcomes are the immediate effects of NIOSH or NIOSH-funded initiatives,
projects, or programs. Often, these effects include changes in learning, awareness,
knowledge, attitudes, skills, opinions, motivations, and intent. While short-term outcomes
are less compelling than intermediate outcomes because no change has yet occurred,
project officers have more control over short-term outcomes than intermediate outcomes.
Collecting data on all types of outcomes, as appropriate, is encouraged.
Intermediate outcomes are specific changes that occur as a result of research outputs.
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Examples of intermediate outcomes include public or private policy changes, conduct of
training or workshops based on project outputs, citations in the literature, inventions and
patents, and adoption of technologies or methods developed by the researcher.
End outcomes are the ultimate goal of the research and the result of what individuals and
organizations do with the knowledge or products generated by the research. Examples of
end outcomes include a) reduction in construction-related illnesses, injuries, fatalities,
near-miss incidents, and/or hazardous exposures and b) improvement in qualitative and/or
quantitative indicators for safety culture and safety climate, safety program administration,
construction safety costs/economics, and safety intervention and/or implementation
effectiveness.
Applicants should provide a brief statement about expected outputs/products of the
research and outcomes of their proposed research in the Description (Abstract) and in the
Research Strategy (Significance) in Section IV.
See Section VIII. Other Information for award authorities and regulations.
Section II. Award Information
Funding Instrument
Cooperative Agreement: A support mechanism used when there will be substantial
Federal scientific or programmatic involvement. Substantial involvement means that, after
award, CDC/NIOSH scientific or program staff will assist, guide, coordinate, or participate
in project activities. See Section VI.2 for additional information about the substantial
involvement for this NOFO.
Application Types Allowed
New
Renewal
Resubmission
Revision
Note to Applicants:
After the December 2023 application due date, only Revision and Resubmission
applications from the funded Center will be accepted for research projects that competed
and were not funded in FY2024. New and Renewal applications will not be accepted for
future application due dates.
The OER Glossary and the SF424 (R&R) Application Guide provide details on these
application types. Only those application types listed here are allowed for this NOFO.
Clinical Trial?
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
Optional: Accepting applications that either propose or do not propose clinical trial(s)
Need help determining whether you are doing a clinical trial?
Funds Available and Anticipated Number of Awards
Estimated Total Funding: $5.75 million total costs (direct and indirect costs) in FY 2024.
NIOSH intends to commit approximately $28.75 million in total costs (direct and indirect)
over the entire project period (up to 5 years).
Anticipated number of awards: NIOSH anticipates funding one award through this
announcement.
The award issued under this NOFO is contingent upon the availability of funds and the
submission of a sufficiently meritorious application.
Award Budget
$5,750,000 Total Costs per budget period
Award Ceiling: $5,750,000 total costs per budget period
Award Floor: $3,000,000 total costs per budget period
It is anticipated that the maximum amount for each application/award will be $5,750,000
in total costs (direct and indirect) for each 12-month budget period.
Award Project Period
5 years
The total project period for an application submitted in response to this NOFO may not
exceed 5 years.
Throughout the project period, CDC's commitment to continuation of awards will depend
on the availability of funds, evidence of satisfactory progress by the recipient (as
documented in required reports), and CDC’s determination that continued funding is in
the best interests of the federal government.
If you are successful and receive a Notice of Award, in accepting the award, you agree
that the award and any activities thereunder are subject to all provisions of 45 CFR Part
75, currently in effect or implemented during the period of the award, other Department
regulations and policies in effect at the time of the award, and applicable statutory
provisions.
HHS/CDC grants policies as described in the HHS Grants Policy Statement will apply to
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
the applications submitted and awards made in response to this NOFO.
Section III. Eligibility Information
1. Eligible Applicants
Eligible Organizations
Higher Education Institutions
Public/State Controlled Institutions of Higher Education
Private Institutions of Higher Education
The following types of Higher Education Institutions are always encouraged to apply for CDC support as
Public or Private Institutions of Higher Education:
o Hispanic-serving Institutions
o Historically Black Colleges and Universities (HBCUs)
o Tribally Controlled Colleges and Universities (TCCUs)
o Alaska Native and Native Hawaiian Serving Institutions
o Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
Nonprofits Other Than Institutions of Higher Education
Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
For-Profit Organizations
Small Businesses
For-Profit Organizations (Other than Small Businesses)
Governments
State Governments
County Governments
City or Township Governments
Special District Governments
Indian/Native American Tribal Governments (Federally Recognized)
Indian/Native American Tribal Governments (Other than Federally Recognized)
Federal Government
Eligible Agencies of the Federal Government
U.S. Territory or Possession
Other
Independent School Districts
Public Housing Authorities/Indian Housing Authorities
Native American Tribal Organizations (other than Federally recognized tribal governments)
Faith-based or Community-based Organizations
Regional Organizations
3. Bona Fide Agents: A Bona Fide Agent is an agency/organization identified by the state as eligible to submit
an application under the state eligibility in lieu of a state application. If applying as a bona fide agent of a state
or local government, a legal, binding agreement from the state or local government as documentation of the
status is required. Attach with "Other Attachment Forms."
4. Federally Funded Research and Development Centers (FFRDCs): FFRDCs are operated, managed, and/or
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
administered by a university or consortium of universities, other not-for-profit or nonprofit organization, or an
industrial firm, as an autonomous organization or as an identifiable separate operating unit of a parent
organization. A FFRDC meets some special long-term research or development need which cannot be met
as effectively by an agency's existing in-house or contractor resources. FFRDC's enable agencies to use
private sector resources to accomplish tasks that are integral to the mission and operation of the sponsoring
agency. For more information on FFRDCs, go to https://gov.ecfr.io/cgi-bin/searchECFR
Foreign Institutions
Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
Foreign components, as defined in the HHS Grants Policy Statement, are not allowed.
Required Registrations
Applicant Organizations
Applicant organizations must complete and maintain the following registrations as
described in the SF 424 (R&R) Application Guide to be eligible to apply for or receive an
award. Applicants must have a valid Unique Entity Identifier (UEI) number in order to
begin each of the following registrations. All registrations must be completed prior to the
application being submitted. Registration can take 6 weeks or more, so applicants should
begin the registration process as soon as possible.
PLEASE NOTE: Effective April 4, 2022, applicants must have a Unique Entity Identifier
(UEI) at the time of application submission. The UEI replaced the Data Universal
Numbering System (DUNS) and is generated as part of SAM.gov registration. Current
SAM.gov registrants have already been assigned their UEI and can view it in SAM.gov
and Grants.gov. Additional information is available on the GSA website, SAM.gov, and
Grants.gov-Finding the UEI.
· System for Award Management (SAM) – Applicants must complete and maintain an
active registration, which requires renewal at least annually. The renewal process may
require as much time as the initial registration. SAM registration includes the assignment
of a Commercial and Government Entity (CAGE) Code for domestic organizations which
have not already been assigned a CAGE Code.
o NATO Commercial and Government Entity (NCAGE) Code – Foreign organizations
must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM.
o Unique Entity Identifier (UEI)- A UEI is issued as part of the SAM.gov registration
process. The same UEI must be used for all registrations, as well as on the grant
application.
· eRA Commons - Once the unique organization identifier is established,
organizations can register with eRA Commons in tandem with completing their Grants.gov
registration; all registrations must be in place by time of submission. eRA Commons
requires organizations to identify at least one Signing Official (SO) and at least one
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
Program Director/Principal Investigator (PD/PI) account in order to submit an application.
· Grants.gov – Applicants must have an active SAM registration in order to complete
the Grants.gov registration. All applicant organizations must register with Grants.gov.
Please visit www.Grants.gov at least 30 days prior to submitting your application to
familiarize yourself with the registration and submission processes. The one-time
registration process will take three to five days to complete. However, it is best to start the
registration process at least two weeks prior to application submission.
Program Directors/Principal Investigators (PD(s)/PI(s)) and Senior/Key Personnel
All Senior/Key Personnel including PD(s)/PI(s) must also work with their institutional
officials to register with the eRA Commons or ensure their existing Principal Investigator
(PD/PI) eRA Commons account is affiliated with the eRA commons account of the
applicant organization. All registrations must be successfully completed and active before
the application due date. Applicant organizations are strongly encouraged to start the eRA
Commons registration process at least four (4) weeks prior to the application due date.
ASSIST requires that applicant users have an active eRA Commons account in order to
prepare an application. It also requires that the applicant organization's Signing Official
have an active eRA Commons Signing Official account in order to initiate the submission
process. During the submission process, ASSIST will prompt the Signing Official to enter
their Grants.gov Authorized Organizational Representative (AOR) credentials in order to
complete the submission, therefore the applicant organization must ensure that their
Grants.gov AOR credentials are active. If the PD/PI is also the organizational Signing
Official, they must have two distinct eRA Commons accounts, one for each role. Obtaining
an eRA Commons account can take up to 2 weeks.
Universal Identifier Requirements and System for Award Management (SAM)
All applicant organizations must obtain a Unique Entity Identifier (UEI) number as the
Universal Identifier when applying for Federal grants or cooperative agreements. The UEI
number is a twelve-digit number assigned by SAM.gov. An AOR should be consulted to
determine the appropriate number. If the organization does not have a UEI number, an
AOR should register through SAM.gov. Note this is an organizational number. Individual
Program Directors/Principal Investigators do not need to register for a UEI number.
Additionally, organizations must maintain the registration with current information at all
times during which it has an application under consideration for funding by CDC and, if an
award is made, until a final financial report is submitted or the final payment is received,
whichever is later.
SAM.gov is the primary registrant database for the Federal government and is the
repository into which an entity must provide information required for the conduct of
business as a recipient. Additional information about registration procedures may be found
at SAM.gov and the SAM.gov Knowledge Base.
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
If an award is granted, the recipient organization must notify potential sub-recipients that
no organization may receive a subaward under the grant unless the organization has
provided its UEI number to the recipient organization.
Eligible Individuals (Program Director/Principal Investigator)
Any individual(s) with the skills, knowledge, and resources necessary to carry out the
proposed research as the Project Director/Principal Investigator (PD/PI) is invited to work
with his/her organization to develop an application for support. Individuals from
underrepresented racial and ethnic groups as well as individuals with disabilities are
always encouraged to apply for HHS/CDC support.
NOTE: The CDC does not make awards to individuals directly.
Responsiveness
A letter of intent is required. The information it contains allows NIOSH staff to estimate the
potential review workload and plan the review.
If an application exceeds the five-year period of performance limit or the total cost limit of
$5,750,000 per budget period (including consortium F&A costs), CDC/NIOSH will consider
the application non-responsive, and it will not enter the peer review process. CDC/NIOSH
will notify the applicant that the application did not meet the submission requirements.
A Center application for a period of performance of 3 years or less will be considered non-
responsive, and CDC/NIOSH will notify the applicant that the application does not meet
the submission requirements and will ask that it be withdrawn.
An application that does not propose multi-scientific collaboration with academic
institutions will be deemed non-responsive, and CDC/NIOSH will request its withdrawal.
For this announcement, NIOSH will not consider or peer review training-only proposals,
service-only programs, non-research proposals, or large institution-based worker safety
and health protection program proposals. These types of applications will be considered
non-responsive, and CDC/NIOSH will request their withdrawal.
Upon receipt, applications will be evaluated for completeness by NIH/CSR and
CDC/NIOSH. CDC/NIOSH will review all applications for responsiveness. Incomplete
and/or non-responsive applications will not be further reviewed for scientific merit.
2. Cost Sharing
This NOFO does not require cost sharing as defined in the HHS Grants Policy Statement.
3. Additional Information on Eligibility
Number of Applications
Only one application per institution (normally identified by having a unique UEI number) is
allowed. As defined in the HHS Grants Policy Statement, applications received in
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
response to the same NOFO generally are scored individually and then ranked with other
applications under peer review in their order of relative programmatic, technical, or
scientific merit. CDC/NIOSH will not accept any application in response to this NOFO that
is essentially the same as one currently pending initial peer review unless the applicant
withdraws the pending application.
The CDC/NIOSH will not accept duplicate or highly overlapping applications under review
at the same time per 2.3.7.4 Submission of Resubmission Application. This means that
the CDC/NIOSH will not accept:
A new (A0) application that is submitted before issuance of the summary statement from the review of
an overlapping new (A0) or resubmission (A1) application.
A resubmission (A1) application that is submitted before issuance of the summary statement from the
review of the previous new (A0) application.
An application that has substantial overlap with another application pending appeal of initial peer
review (see 2.3.9.4 Similar, Essentially Identical, or Identical Applications).
Section IV. Application and Submission Information
1. Requesting an Application Package
The application forms package specific to this opportunity must be accessed through
ASSIST or an institutional system-to-system (S2S) solution. A button to apply using
ASSIST is available in Part 1 of this NOFO. See your administrative office for instructions
if you plan to use an institutional system-to-system solution.
Applicants must use ASSIST or an institutional system-to-system (S2S) solution to
prepare and submit their multi-project applications through Grants.gov to NIH. Although all
NIH multi-project applications flow through Grants.gov, the Grants.gov Workspace
application preparation system does NOT support multi-project applications
To use ASSIST, applicants must visit https://public.era.nih.gov where you can login using
your eRA Commons credentials and enter the Notice of Funding Opportunity Number to
initiate the application and begin the application preparation process.
If you experience problems accessing or using ASSIST, you can refer to the ASSIST
Online Help Site at: https://era.nih.gov/erahelp/assist. Additional support is available from
the NIH eRA Service desk via: http://grants.nih.gov/support/index.html.
Email: commons@od.nih.gov.
Phone: 301-402-7469 or (toll-free) 1-866-504-9552.
Hours: Monday - Friday, 7 a.m. to 8 p.m. Eastern Time, excluding Federal holidays.
2. Content and Form of Application Submission
It is critical that applicants follow the Multi-Project (M) Instructions in the SF424 (R&R)
Application Guide, except where instructed in this notice of funding opportunity to do
otherwise. Conformance to the requirements in the Application Guide is required and
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
strictly enforced. Applications that are out of compliance with these instructions may be
delayed or not accepted for review. The package associated with this NOFO includes all
applicable mandatory and optional forms. Please note that some forms marked optional in
the application package are required for submission of applications for this NOFO. Follow
the instructions in the SF-424 Application Guide to ensure you complete all appropriate
“optional” components.
When using ASSIST, all mandatory forms will appear as separate tabs at the top of the
Application Information screen; applicants may add optional forms available for the NOFO
by selecting the Add Optional Form button in the left navigation panel.
Letter of Intent
Due Date: November 1, 2023. Thereafter, 30 days prior to the future submission due
dates.
A letter of intent is required, the information that it contains allows NIOSH staff to
estimate the potential review workload and plan the review.
By the date listed in Part 1. Overview Information, prospective applicants are asked to
submit a letter of intent that includes the following information:
Descriptive title of proposed Center
Titles for each proposed research project
Name(s), address(es), email(s), and telephone number(s) of the PD(s)/PI(s) for the Center
Names of all other component leads
Participating institution(s)
Number and title of this funding opportunity
The letter of intent should be sent to:
Michael Goldcamp, PhD
National Institute for Occupational Safety and Health (NIOSH)
Centers for Disease Control and Prevention (CDC)
Telephone: 304-285-5951
Email: MGoldcamp@cdc.gov
Page Limitations
All page limitations described in the SF424 Application Guide and the Table of Page
Limits must be followed, with the following exceptions or additional requirements for this
NOFO:
Only include proposed (prospective) work in the research strategy attachment to the PHS
398 Research Plan (i.e., "3. Research Strategy"). Past performance and/or prior
accomplishments, whether for new or renewal applicants, is limited to 6 pages per
component and should be attached to the Appendix of the PHS 398 Research Plan (i.e.,
"13. Appendix"). Related publications for the particular proposed component, whether for
new or renewal applicants, should be attached to the progress report publication list of the
PHS 398 Research Plan (i.e., "4. Progress Report Publication List"). There is no page limit
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
for related publications attachments.
Pages that exceed page limits described in this NOFO will be removed and not forwarded
for peer review.
Available Component Research Required/OptionalMinimumMaximum
Components Type for Strategy
Submission /Program
Plan Page
Limit
Overall Overall 12 Required 1 1
Planning, Admin Core 12 Required 1 1
Administration,
and Evaluation
Core
Construction Data Core 12 Required 1 1
Industry Data
and Statistical
Core
Communication,Communication12 Required 1 1
Outreach, and Core
Education Core
Research to Research to 12 Required 1 1
Practice Core Practice
Applied Project 12 Required 1 15
Research
Projects
Note: References are not included in the page limits
Format for Attachments
Designed to maximize system-conducted validations, multiple separate attachments are
required for a complete application. When the application is received by the agency, all
submitted forms and all separate attachments are combined into a single document that is
used by peer reviewers and agency staff. Applicants should ensure that all attachments
are uploaded to the system.
CDC requires all text attachments to the Adobe application forms be submitted as
PDFs and that all text attachments conform to the agency-specific formatting
requirements noted in the SF424 (R&R) Application Guide at How to Apply -
Application Guide.
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
Instructions for the Submission of Multi-Component Applications
The following section supplements the instructions found in the SF424 (R&R) Application
Guide, and should be used for preparing a multi-component application.
Revision applications must include an Overall component and the components that are
affected by the revision. Therefore, the component requirements listed below may not
apply to the revision application.
The application should consist of the following required components:
Overall
Planning, Administrative, and Evaluation Core
Construction Industry Data and Statistical Core
Communication, Outreach, and Education Core
Research-to-Practice Core
Applied Research Projects
Any application that does not include all required components will be considered non-
responsive and will not be reviewed.
Special Requirements for this Announcement
The applicant should consider the following recipient requirements when developing their application and
budget request:
a. Participation in monthly strategic and coordination meetings or teleconferences with the NIOSH Office
of Construction Safety and Health and the Office of Extramural Programs.
b. Participation in monthly grant administration teleconferences with CDC and NIOSH grants offices.
c. Serving as an active member of the NORA Construction Sector Council and its workgroups providing
periodic National Construction Center program & research updates and data.
d. Planning and conducting an annual national construction research and research-to-practice meeting for
overall advancement of safety and health in the U.S. construction industry. External experts may be
needed for these meetings to accomplish the necessary objectives. The public meeting agenda and
location(s) will be developed in cooperation with the NIOSH Office of Construction Safety and Health.
Meeting materials, resources and/or program booklet will be made publicly available.
e. Recordkeeping for implementation and compliance monitoring for HHS and other administrative
requirements that will apply for this announcement. Ethical, human, and animal research protections
(such as the HHS Revised Common Rule), as well as policies for scientific integrity and data
management and access (for example, a Data Management Plan) will apply. Detailed descriptions for a
multi-institution-involved Data Management Plan (and data portals) will be required. Other HHS/CDC
Administrative Policy Requirements will apply. See the CDC Office of Grants Services website for grant
administrative requirements.
f. Planning and conducting brief, regular (for example, monthly) construction safety and health
seminars/webinars, such as on injury and illness data, data-driven best practices, emerging issues in
construction safety and health, prevention through design & modeling/BIM, human and/or mechanical
factors, and U.S. construction industry characteristics and indicators.
g. Providing construction safety, health, and industry data and statistical consulting services for
external/public requests to the maximum extent allowed by multi-agency policies and agreements. This
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
will require access or agreements for relevant data sources and adequate professional staffing
throughout the funding period. Annual performance reports will include a summary of data and consulting
services provided.
h. Providing construction-focused research-to-practice and health communication consulting services for
external requests. The recipient is expected to have an adequate mix of full-time, professional staff
members offering the disciplines and skills for this service. These staff members may also serve as key or
support personnel on specific proposals.
i. Preparing an Annual Report of Major Accomplishments and Research Impact for Construction Safety
and Health. A summary report is due at the end of each 12-month budget period and must be suitable for
the NIOSH website (for example, compliant with Rehabilitation Act Section 508). A 10-page limit will
apply.
j. Developing and maintaining a publicly accessible data gateway or portal for near-real-time research
data and data descriptions/instructions for public use. Maintenance of the gateway/portal (including IT
support) is required throughout the entire funding period. The applicant is to clearly describe
arrangements or agreements with proposal sub-recipients for data access, to ensure a cogent plan.
Letters of commitment from consortia research institutions are strongly encouraged.
k. Addressing NIOSH comments for draft reports, educational and other materials, including data
summary, fact sheet, and the Annual Report.
l. Assisting in identifying and writing research impacts and outcomes in response to congressional and
other requests to CDC and NIOSH. These activities are typically time critical and require prompt input.
m. Providing injury, illness, and other indicator data regularly. Online or electronic reports and summaries
are expected annually. Timely responses are expected to data requests from NIOSH, state and federal
OSHA, and others each year.
n. Compliance with limiting the use of CDC/NIOSH grant funds to support one international trip for sub-
award researchers over the lifetime of their research projects. Applicants must clearly state the purpose
of the trip, and how it will benefit the safety and health of U.S. construction workers.
o. Compliance with the HHS Revised Common Rule definition of a clinical trial and the applicable related
requirements (for instance, a data safety monitoring plan; registration at ClinicalTrial.gov).
Note: Approximate budget allocation guidance has been provided in Section I.2.
Approach. Applicants may request with justification more or less funding for any of the
Cores provided they do not exceed the total costs allowed under this NOFO and that all
required Cores are included in the application.
Note: Research Projects will be listed in the final application in the order in which they
were entered in ASSIST as Research-Project 1, Research-Project 2, etc. The maximum
number of the entire Applied Research Core is 15.
Please enter in ASSIST in the following order:
Overall Component
When preparing your application, use Component Type ‘Overall’.
All instructions in the SF424 (R&R) Application Guide must be followed, with the following
additional instructions, as noted.
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
SF424 (R&R) Cover (Overall)
Complete entire form.
PHS 398 Cover Page Supplement (Overall)
Research & Related Other Project Information (Overall)
Follow standard instructions.
Project Summary/Abstract: Provide a succinct summary of the proposed work for the
entire Center.
Project Narrative: In 1-3 sentences, describe the relevance of the research and outreach
efforts proposed by the Center.
Facilities and other Resources: Provide a description of all resources for all proposed
components in the Facilities and Other Resources attachment. The information will be
used to evaluate the quality of the overall environment for the Center.
Equipment: Do not include. Equipment should be identified in the appropriate
components. Equipment that is shared across components should be described in the
Planning, Administration, and Evaluation Core.
Project/Performance Site Location(s) (Overall)
Enter primary site only.
A summary of Project/Performance Sites in the Overall section of the assembled
application image in eRA Commons compiled from data collected in the other components
will be generated upon submission.
Research & Related Senior/Key Person Profile (Overall)
Include only the Project Director/Principal Investigator (PD/PI) and any multi-PDs/PIs (if
applicable to this NOFO) for the entire application. Component leads and other senior/key
individuals should only be listed in the components in which they are active.
The Center will be an identifiable organizational unit formed by a single institution or a
consortium of cooperating institutions. Therefore, lines of authority must be clearly
specified. Each applicant institution will name a Director (Project Director/Principal
Investigator, PD/PI) who will be the key figure in the administration, management and
coordination of the cooperative agreement. This individual will be responsible for the
organization and operation of the Center. The PD/PI should be a scientific leader
experienced in their field of research and must be able to coordinate, integrate, and
provide guidance in the establishment of the cores, programs, and projects.
Each Senior/Key Person, including the PD/PI, is allowed one biosketch for the entire
application. If an individual will participate on multiple components, attach the biosketch to
any single component. The biosketches must be comprehensive, covering multiple roles if
a single individual has multiple roles within the application.
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
A summary of Senior/Key Persons followed by their Biographical Sketches in the Overall
section of the assembled application image in eRA Commons will be generated upon
submission.
Budget (Overall)
The only budget information included in the Overall component is the Estimated Project
Funding section of the SF424 (R&R) Cover.
A budget summary in the Overall section of the assembled application image in eRA
Commons compiled from detailed budget data collected in the other components will be
generated upon submission.
PHS 398 Research Plan (Overall)
Introduction to Application: For Resubmission and Revision applications ONLY, an
Introduction to Application is required in the Overall component.
Specific Aims: Describe the aims of the overall Center and outline how components will
contribute to these aims. Provide a concise overview of the applicant’s intent and the
potential to function as a NIOSH National Construction Center. It should include the short,
intermediate and long-term goals that are proposed. Applicants should describe the
intended synergy, collaboration, and integration of major activities and/or leadership or
Key Personnel who are responsible for the Center’s goal attainment. Describe plans to
collaborate and cooperate with key federal, non- federal and industry stakeholders.
Research Strategy: Provide an overview that describes the key scientific aspects of the Center and how
the proposed Center structure (cores, programs, and projects) addresses the purpose and objectives
described in this funding announcement. The application should be comprised of interrelated projects,
programs, and cores, each capable of standing on its own merit but complementary and necessary for
accomplishing the Center's proposed objectives. This section provides the applicant an opportunity to
give a conceptual framework for the Center and a broad strategy for accomplishing the strategic goals. It
also allows the applicant to collectively address the proposed research projects as well as identifying
connections with Communication, Outreach, and Education Core activities.
Focusing on the Center as a whole, address (1) the importance of the overall goals of the Center and the
critical barrier(s) to progress in the field that will be the focus, (2) how the resources of the proposed
Center will improve scientific knowledge, technical capability, and/or improved practice and outreach, and
(3) how the concepts, methods, technologies, services, or interventions that drive the construction
occupational safety and health field will be changed if the proposed aims are achieved.
Considering the entire Center, describe how the proposed research seeks to shift current research,
outreach or practice paradigms through use of novel concepts, approaches, methodologies,
instrumentation, or interventions. Does the proposed work refine, improve, or apply in a new way
present/existing/current concepts, approaches, methodologies, instrumentation, or interventions?
Include the major proposed efforts and studies and show how the cores, programs, and projects
complement each other or are interdependent. Describe the mechanisms that will ensure the coherence
and cohesiveness of the Center while maintaining a multidisciplinary focus.
Discuss the research projects individually and collectively as a research core and provide a clear and
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
considered agenda supporting the Centers' overall efforts. Applicants should address the following:
Provide a brief description of the overall research objectives.
Describe how all research projects within the Center will be managed, monitored, and coordinated.
Identify the category of the proposed individual research projects (i.e., intervention, implementation, or
surveillance).
Provide a brief description of the Pilot Program (this is an optional component).
Consider both the NIOSH strategic plan and NORA construction research agenda as you develop
proposals and identify the strategic and intermediate goals your research will support. Also review and
consider the 2018 NIOSH Construction Program Review report and recommendations. Propose
innovative or novel approaches to addressing the major health and safety issues facing the U.S.
construction workforce and for moving the field forward through action designed to achieve these goals.
An important consideration is demonstrating integrated research programs and/or projects, as well as
nationally coordinated construction occupational safety and health research, dissemination, and
implementation efforts for the entire United States.
Clearly describe how your proposed work in the construction sector will address the stated strategic and
intermediate goals, and clearly identify the health and safety cross-sector(s) being addressed. Although
the primary focus of this funding announcement is the construction sector, indicate whether and how the
proposed projects or aspects of projects may be relevant to other NORA sectors.
Provide data to support the selection of the proposed work, such as morbidity rates, mortality rates, or
indicators of the size of the population at risk, including estimates of the target population’s potential risk
of exposure to the hazard, frequency of exposure, or sociodemographic factors such as age, gender, and
race/ethnicity. Similarly, you may provide qualitative data that describe exposures, the magnitude of the
problem, and potential benefits and impacts of addressing the issue. Qualitative data may be necessary
when the nature of the exposure or population at risk make collecting large-scale, representative,
quantitative data difficult.
NIOSH has a number of resources available to researchers, including Worker Health Charts. NIOSH
gathers worker health data from the BLS to create these specialized charts to assess the rates,
distribution, and trends in workplace injuries, illnesses, and deaths. These data help provide context and
estimate the burden of the problems addressed, the need for the proposed work, the impact on the
workforce, and the potential long-term benefits of the proposed projects and activities. Economic metrics
such as the societal cost, medical cost, impact on productivity, and disability costs also provide context
for these issues.
Letters of Support: Include signed letters of support or collaboration from participating institutions.
These can be included in the overall component, or with specific components if closely related to the aims
in those cores, programs, or projects.
Resource Sharing Plan:
Individuals are required to comply with the instructions for the Resource Sharing Plans as provided in the
SF424 (R&R) Application Guide with the following modifications.
Applicants that plan to collect public health data must submit a Data Management Plan (DMP) in the
Resource Sharing Plan section of the PHS 398 Research Plan Component of the application. A DMP is
required for each collection of public health data proposed. Applicants who contend that the public health
data they collect or create are not appropriate for release must justify that contention in the DMP
submitted with their application for CDC funds.
The DMP may be outlined in a narrative format or as a checklist but, at a minimum, should include:
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
• A description of the data to be collected or generated in the proposed project;
• Standards to be used for the collected or generated data;
• Mechanisms for, or limitations to, providing access to and sharing of the data (include a description of
provisions for the protection of privacy, confidentiality, security, intellectual property, or other rights - this
section should address access to identifiable and de-identified data);
• Statement of the use of data standards that ensure all released data have appropriate documentation
that describes the method of collection, what the data represent, and potential limitations for use; and
• Plans for archiving and long-term preservation of the data, or explaining why long-term preservation and
access are not justified (this section should address archiving and preservation of identifiable and de-
identified data).
CDC OMB-approved templates may be used (e.g., NCCDPHP template).
Appendix:
Past performance and/or prior accomplishments within the last 5 years, whether for new or renewal
applicants, are limited to 6 pages. Follow all instructions for the Appendix as described in the SF424
(R&R) Application Guide. Only the items listed in NOT-OD-17-098, plus additional items specifically listed
in this funding opportunity announcement, are allowed.
Note: The applicant should include a Human Subjects summary table that lists all proposed relevant
cores, programs, and projects along with human subjects information (project title, performance sites,
FWAs, IRB approval date/status).
PHS Human Subjects and Clinical Trials Information (Overall)
When involving human subjects research, clinical research, and/or NIH-defined clinical trials follow all
instructions for the PHS Human Subjects and Clinical Trials Information form in the SF424 (R&R)
Application Guide, with the following additional instructions:
If you answered “Yes” to the question “Are Human Subjects Involved?” on the R&R Other Project
Information form, there must be at least one human subjects study record using the Study Record: PHS
Human Subjects and Clinical Trials Information form or a Delayed Onset Study record within the
application. The study record(s) must be included in the component(s) where the work is being done,
unless the same study spans multiple components. To avoid the creation of duplicate study records, a
single study record with sufficient information for all involved components must be included in the Overall
component when the same study spans multiple components.
Study Record: PHS Human Subjects and Clinical Trials Information
All instructions in the SF424 (R&R) Application Guide must be followed
Delayed Onset Study
Note: Delayed onset does NOT apply to a study that can be described but will not start
immediately (i.e., delayed start). All instructions in the SF424 (R&R) Application Guide
must be followed.
Planning, Administration and Evaluation Core (Required)
When preparing your application, use Component Type ‘Admin Core.’
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
All instructions in the SF424 (R&R) Application Guide must be followed.
SF424 (R&R) Cover (Planning, Administration and Evaluation Core)
Complete only the following fields:
Applicant Information
Type of Applicant (optional)
Descriptive Title of Applicant’s Project
Proposed Project Start/Ending Dates
PHS 398 Cover Page Supplement (Planning, Administration, and Evaluation Core)
Research & Related Other Project Information (Planning, Administration and Evaluation
Core)
Human Subjects: Answer only the ‘Are Human Subjects Involved?’ and 'Is the Project
Exempt from Federal regulations?’ questions.
Vertebrate Animals: Answer only the ‘Are Vertebrate Animals Used?’ question.
Project Narrative: In 1-3 sentences, describe the relevance of the planning and
evaluation efforts proposed in the Core.
Project /Performance Site Location(s) (Planning, Administration and Evaluation Core)
List all performance sites that apply to the specific component.
Note: The Project Performance Site form allows up to 300 sites, prior to using additional
attachment for additional entries.
Research & Related Senior/Key Person Profile (Planning, Administration and Evaluation
Core)
The Program Director/Principal Investigator of the proposed Center should also be the Planning,
Administration, and Evaluation Core Lead. In the Project Director/Principal Investigator section, use
Project Role of 'Other' with Category of 'Center Director' and provide a valid eRA Commons ID in the
Credential field. The biographical sketch should present evidence of scientific expertise relevant to the
themes of the Center and demonstrate the capacity for the leadership of the Center.
In the additional Senior/Key Profiles section, list Senior/Key persons that are working in the component.
An Associate (or Deputy) Director may be named who will be involved in the administrative and scientific
efforts of the Center. If named, specify Project Role of 'Other' with Category of 'Associate Director.'
Include a single Biographical Sketch for each Senior/Key person listed in the application regardless of the
number of components in which they participate. When a Senior/Key person is listed in multiple
components, the Biographical Sketch can be included in any one component.
Budget (Planning, Administration and Evaluation Core)
Budget forms appropriate for the specific component will be included in the application
package.
For this NOFO, CDC/NIOSH requires a detailed budget for each budget period requested. Each Core
component should contain all budget and subaward information including indirect costs and consortium
facilities and administration (F&A) costs.
Approximate budget allocation guidance has been provided in Section I.2. Approach.
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
Applicants may request with justification more or less funding for any of the Cores
provided they do not exceed the total costs allowed under this NOFO and that all required
Cores are included in the application.
The Pilot Study Program is an optional element for the Planning, Administration, and
Evaluation Core and is intended to assist the Center in addressing new or emerging
issues that were not present or recognizable at the time of application.
Note: The R&R Budget form included in many of the component types allows for up to 100
Senior/Key Persons in section A and 100 Equipment Items in section C prior to using
attachments for additional entries. All other SF424 (R&R) instructions apply.
PHS 398 Research Plan (Planning, Administration and Evaluation Core)
Introduction to Application: For Resubmission and Revision applications, an Introduction to Application
is allowed for each component.
Specific Aims: Clearly state how the Planning, Administration, and Evaluation Core will
contribute to the goals of the Center and how this core integrates with other projects,
programs, and cores. Provide an overview of how the Planning, Administration, and
Evaluation Core will set the overall direction of the Center and ensure optimal utilization of
Center resources.
This Core should include coordination and management and Center activities, advisory
committees, and evaluation of programs and activities. This Core should also include
evaluation plans, organization chart, and description of key personnel. Participation in
periodic scientific meetings, conferences, and workshops is encouraged and may be
requested under the Planning, Administration, and Evaluation and/or other relevant
Core(s).
Research Strategy: Organize the Research Strategy of the Planning, Administration, and
Evaluation Core into the required and optional elements:
Center Planning and Administration
Evaluation Program
Pilot study program (optional)
Required Center administrative activities include establishing and maintaining advisory committees,
ensuring human subject and animal use protocols are obtained and maintained (as applicable), and
meeting all reporting requirements as detailed in the notice of award. The principal investigators, project
directors, and other key personnel in the Center are expected to maintain close communication and
collaboration to ensure that the Center cohesively addresses multiple aspects of the issues in the
construction industry they are working to remediate. The core should develop and maintain a vision and
goals that the Center will work toward achieving during the course of the performance period and beyond.
The National Construction Center should establish (or maintain) an advisory board of stakeholders
knowledgeable about construction health and safety in the nation.
The Evaluation Program is expected to include descriptions about activities, outputs, intermediate and
end outcomes as well as plans to serve as the Center’s strategic roadmap as it plans, coordinates,
implements, and assesses its impact over the funding period (and some intermediate and end outcomes
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
that may occur beyond the period of funding). Consideration should be given to factors including, but not
limited to, the NIOSH Strategic Plan, burden and need information, stakeholder input, evaluation
feedback, Center expertise, and previous work. The Evaluation Program should include tracking of
outputs and identifying, collecting, and documenting intermediate outcomes that contribute to the Center’s
goals. The Evaluation Program will assist in planning and implementing evaluation efforts at the individual
project and program level, particularly as it applies to the efficacy and effectiveness of proposed
interventions. Any other evaluation activities that the Center plans to conduct for the purposes of
assessing impact or Center/program improvement should also be incorporated into the Evaluation
Program.
The Pilot Study Program is intended to assist the Center in addressing new or emerging problems that
were not present or recognizable at the time of application. Applicants should describe the process by
which they plan to identify, prioritize, and address newly arising concerns. Applicants should describe
how the program will be managed and utilized to respond to emerging threats.
Letters of Support: Provide any letters of support that are specific to this core. Include a
Letter of Support for each Advisory Committee member.
Resource Sharing Plan:
Individuals are required to comply with the instructions for the Resource Sharing Plans as provided in the
SF424 (R&R) Application Guide with the following modifications.
Applicants that plan to collect public health data must submit a Data Management Plan (DMP) in the
Resource Sharing Plan section of the PHS 398 Research Plan Component of the application. A DMP is
required for each collection of public health data proposed. Applicants who contend that the public health
data they collect or create are not appropriate for release must justify that contention in the DMP
submitted with their application for CDC funds.
The DMP may be outlined in a narrative format or as a checklist but, at a minimum, should include:
• A description of the data to be collected or generated in the proposed project;
• Standards to be used for the collected or generated data;
• Mechanisms for, or limitations to, providing access to and sharing of the data (include a description of
provisions for the protection of privacy, confidentiality, security, intellectual property, or other rights - this
section should address access to identifiable and de-identified data);
• Statement of the use of data standards that ensure all released data have appropriate documentation
that describes the method of collection, what the data represent, and potential limitations for use; and
• Plans for archiving and long-term preservation of the data, or explaining why long-term preservation and
access are not justified (this section should address archiving and preservation of identifiable and de-
identified data).
CDC OMB-approved templates may be used (e.g., NCCDPHP template).
Appendix:
Past performance and/or prior accomplishments within the last 5 years, whether for new or renewal
applicants, are limited to 6 pages. Follow all instructions for the Appendix as described in the SF424
(R&R) Application Guide. Only the items listed in NOT-OD-17-098, plus additional items specifically listed
in this funding opportunity announcement, are allowed.
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
PHS Human Subjects and Clinical Trials Information (Planning, Administration, and
Evaluation Core)
When involving human subjects research, clinical research, and/or NIH-defined clinical trials follow all
instructions for the PHS Human Subjects and Clinical Trials Information form in the SF424 (R&R)
Application Guide, with the following additional instructions:
If you answered “Yes” to the question “Are Human Subjects Involved?” on the R&R Other Project
Information form, you must include at least one human subjects study record using the Study Record:
PHS Human Subjects and Clinical Trials Information form or a Delayed Onset Study record.
Study Record: PHS Human Subjects and Clinical Trials Information
All instructions in the SF424 (R&R) Application Guide must be followed.
Delayed Onset Study
Note: Delayed onset does NOT apply to a study that can be described but will not start
immediately (i.e., delayed start).All instructions in the SF424 (R&R) Application Guide
must be followed.
Construction Industry Data and Statistical Core (Required)
When preparing your application, use Component Type ‘Data Core.’
All instructions in the SF424 (R&R) Application Guide must be followed, with the following
additional instructions, as noted.
SF424 (R&R) Cover (Construction Industry Data and Statistical Core)
Complete only the following fields:
Applicant Information
Type of Applicant (optional)
Descriptive Title of Applicant’s Project
Proposed Project Start/Ending Dates
PHS 398 Cover Page Supplement (Construction Industry Data and Statistical Core)
Research & Related Other Project Information (Construction Industry Data and
Statistical Core)
Human Subjects: Answer only the 'Are Human Subjects Involved?' and 'Is the Project Exempt from
Federal regulations?' questions.
Vertebrate Animals: Answer only the 'Are Vertebrate Animals Used?' question.
Project Narrative: In 1-3 sentences, describe the relevance of the research proposed in the Core.
Project /Performance Site Location(s) (Construction Industry Data and Statistical
Core)
List all performance sites that apply to the specific component.
Note: The Project Performance Site form allows up to 300 sites, prior to using additional attachment for
additional entries.
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
Research & Related Senior/Key Person Profile (Construction Industry Data and
Statistical Core)
In the Project Director/Principal Investigator section of the form, use Project Role of ‘Other’ with Category
of ‘Core Lead’ and provide a valid eRA Commons ID in the Credential field. In the additional Senior/Key
Profiles section, list Senior/Key persons that are working in the component.
Include a single Biographical Sketch for each Senior/Key person listed in the application regardless of the
number of components in which they participate. When a Senior/Key person is listed in multiple
components, the Biographical Sketch can be included in any one component.
The Core lead should have the expertise appropriate to manage all aspects of the Core successfully.
Budget (Construction Industry Data and Statistical Core)
Budget forms appropriate for the specific component will be included in the application package.
For this NOFO, CDC/NIOSH requires a detailed budget for the initial budget year and a budget for each
consecutive year of support.
Approximate budget allocation guidance has been provided in Section I.2. Approach. Applicants may
request with justification more or less funding for any of the Cores provided they do not exceed the total
costs allowed under this NOFO and that all required Cores are included in the application.
Note: The R&R Budget form included in many of the component types allows for up to 100 Senior/Key
Persons in section A and 100 Equipment Items in section C prior to using attachments for additional
entries. All other SF424 (R&R) instructions apply.
PHS 398 Research Plan (Construction Industry Data and Statistical Core)
Introduction to Application: For Resubmission and Revision applications, an Introduction to Application
is allowed for each component.
Specific Aims: Describe the broad, long-range, and short-term objectives and goals of the proposed
Construction Industry Data and Statistical Core. Outline a framework how the utilization of data will
address key research questions and objectives related to construction-related injury, illness, deaths,
industry characteristics, and relevant employment, demographic, and economic variables.
Research Strategy:
Describe how the Core activities will contribute to meeting the Center’s goals and objectives and explain
the rationale for selection of the methods, technologies, data, and approaches proposed to accomplish
the specific aims of the Center.
Describe the data acquisition process and sources that the Construction Industry Data and Statistical
Core will utilize to collect construction-related data. Explain the rationale for selecting these sources and
outline quality control measures to ensure the accuracy and reliability of the acquired data.
Outline the analytical approaches and statistical methods that will be employed to analyze and interpret
the collected data. Justify the chosen methods based on their appropriateness for addressing the
research questions and objectives identified in the specific aims.
Detail the mechanisms for data dissemination, including the development of reports, dashboards, and
other tools to effectively communicate the acquired insights, trends, and findings to the construction
industry stakeholders. Discuss strategies for reaching a wide audience and promoting the practical
application of the data-driven knowledge.
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
Letters of Support: Provide any letters of support that are specific to this core.
Resource Sharing Plan:
Individuals are required to comply with the instructions for the Resource Sharing Plans as provided in the
SF424 (R&R) Application Guide with the following modifications.
Applicants that plan to collect public health data must submit a Data Management Plan (DMP) in the
Resource Sharing Plan section of the PHS 398 Research Plan Component of the application. A DMP is
required for each collection of public health data proposed. Applicants who contend that the public health
data they collect or create are not appropriate for release must justify that contention in the DMP
submitted with their application for CDC funds.
The DMP may be outlined in a narrative format or as a checklist but, at a minimum, should include:
• A description of the data to be collected or generated in the proposed project;
• Standards to be used for the collected or generated data;
• Mechanisms for, or limitations to, providing access to and sharing of the data (include a description of
provisions for the protection of privacy, confidentiality, security, intellectual property, or other rights - this
section should address access to identifiable and de-identified data);
• Statement of the use of data standards that ensure all released data have appropriate documentation
that describes the method of collection, what the data represent, and potential limitations for use; and
• Plans for archiving and long-term preservation of the data, or explaining why long-term preservation and
access are not justified (this section should address archiving and preservation of identifiable and de-
identified data).
CDC OMB-approved templates may be used (e.g., NCCDPHP template).
Appendix:
Past performance and/or prior accomplishments within the last 5 years, whether for new or renewal
applicants, are limited to 6 pages. Follow all instructions for the Appendix as described in the SF424
(R&R) Application Guide. Only the items listed in NOT-OD-17-098, plus additional items specifically listed
in this funding opportunity announcement, are allowed.
PHS Human Subjects and Clinical Trials Information (Construction Industry Data and
Statistical Core)
When involving human subjects research, clinical research, and/or NIH-defined clinical trials follow all
instructions for the PHS Human Subjects and Clinical Trials Information form in the SF424 (R&R)
Application Guide, with the following additional instructions:
If you answered “Yes” to the question “Are Human Subjects Involved?” on the R&R Other Project
Information form, you must include at least one human subjects study record using the Study Record:
PHS Human Subjects and Clinical Trials Information form or a Delayed Onset Study record.
Study Record: PHS Human Subjects and Clinical Trials Information
All instructions in the SF424 (R&R) Application Guide must be followed
Delayed Onset Study
Note: Delayed onset does NOT apply to a study that can be described but will not start immediately (i.e.,
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
delayed start). All instructions in the SF424 (R&R) Application Guide must be followed.
Communication, Outreach, and Education Core (Required)
When preparing your application, use Component Type ‘Communication Core.’
All instructions in the SF424 (R&R) Application Guide must be followed.
SF424 (R&R) Cover (Communication, Outreach, and Education Core)
Complete only the following fields:
Applicant Information
Type of Applicant (optional)
Descriptive Title of Applicant’s Project
Proposed Project Start/Ending Dates
PHS 398 Cover Page Supplement (Communication, Outreach, and Education Core)
Research & Related Other Project Information (Communication, Outreach, and
Education Core)
Human Subjects: Answer only the ‘Are Human Subjects Involved?’ and 'Is the Project Exempt from
Federal regulations?’ questions.
Vertebrate Animals: Answer only the ‘Are Vertebrate Animals Used?’ question.
Project Narrative: In 1-3 sentences, describe the relevance of the research and outreach efforts
proposed in the Core.
Project /Performance Site Location(s) (Communication, Outreach, and Education
Core)
List all performance sites that apply to the specific component.
Note: The Project Performance Site form allows up to 300 sites, prior to using additional attachment for
additional entries.
Research & Related Senior/Key Person Profile (Communication, Outreach, and
Education Core)
In the Project Director/Principal Investigator section of the form, use Project Role of ‘Other’ with Category
of ‘Core Lead’ and provide a valid eRA Commons ID in the Credential field. In the additional Senior/Key
Profiles section, list Senior/Key persons that are working in the component.
Include a single Biographical Sketch for each Senior/Key person listed in the application regardless of the
number of components in which they participate. When a Senior/Key person is listed in multiple
components, the Biographical Sketch can be included in any one component.
The Core lead should have the expertise appropriate to manage all aspects of the Core successfully.
Budget (Communication, Outreach, and Education Core)
Budget forms appropriate for the specific component will be included in the application package.
For this NOFO, CDC/NIOSH requires a detailed budget for the initial budget year and a budget for each
consecutive year of support.
Approximate budget allocation guidance has been provided in Section I.2. Approach. Applicants may
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
request with justification more or less funding for any of the Cores provided they do not exceed the total
costs allowed under this NOFO and that all required Cores are included in the application.
Note: The R&R Budget form included in many of the component types allows for up to 100 Senior/Key
Persons in section A and 100 Equipment Items in section C prior to using attachments for additional
entries. All other SF424 (R&R) instructions apply.
PHS 398 Research Plan (Communication, Outreach, and Education Core)
Introduction to Application: For Resubmission and Revision applications, an Introduction to Application
is allowed for each component.
Specific Aims: Briefly describe the overall specific aims, and the proposed activities and services of the
Communication, Outreach, and Education Core. Clearly describe the relationship of the Core to the
overall Center’s goals and how the proposed activities relate to the other research projects and cores.
Describe the anticipated strategies for dissemination and/or implementation of research findings.
Research Strategy: The Communication, Outreach, and Education Core should be broad in scope and
prioritize activities that will have an impact on construction worker health and safety. This Core must
develop an outreach plan that aligns with the Center's goals and considers the diverse needs of
stakeholders to support successful transfer and adoption by intermediaries and/or end users. When
developing the plan, the Center should consider its activities, anticipated project outputs and primary
target audiences. The applicant should describe the anticipated strategies for dissemination and
implementation of research findings, including the audiences to be reached and the methods to reach
those audiences.
The Communication, Outreach, and Education Core should have an adaptable, scalable plan for the
entire project period. This should include plans for sustainable partnerships with diverse stakeholder
groups that help improve occupational safety and health in the construction sector.
The plan should also reflect how personnel in this core will work with those in other components to better
integrate, at project conception, consideration of primary target audiences, modalities (the most
appropriate outputs) to reach them, and a plan for achieving impact.
Letters of Support: Provide any letters of support that are specific to this core, particularly focusing on
non-profits, community organizations, stakeholders, and other key partners in outreach and educational
efforts.
Resource Sharing Plan:
Individuals are required to comply with the instructions for the Resource Sharing Plans as provided in the
SF424 (R&R) Application Guide with the following modifications.
Applicants that plan to collect public health data must submit a Data Management Plan (DMP) in the
Resource Sharing Plan section of the PHS 398 Research Plan Component of the application. A DMP is
required for each collection of public health data proposed. Applicants who contend that the public health
data they collect or create are not appropriate for release must justify that contention in the DMP
submitted with their application for CDC funds.
The DMP may be outlined in a narrative format or as a checklist but, at a minimum, should include:
• A description of the data to be collected or generated in the proposed project;
• Standards to be used for the collected or generated data;
• Mechanisms for, or limitations to, providing access to and sharing of the data (include a description of
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provisions for the protection of privacy, confidentiality, security, intellectual property, or other rights - this
section should address access to identifiable and de-identified data);
• Statement of the use of data standards that ensure all released data have appropriate documentation
that describes the method of collection, what the data represent, and potential limitations for use; and
• Plans for archiving and long-term preservation of the data, or explaining why long-term preservation and
access are not justified (this section should address archiving and preservation of identifiable and de-
identified data).
CDC OMB-approved templates may be used (e.g., NCCDPHP template).
Appendix:
Past performance and/or prior accomplishments within the last 5 years, whether for new or renewal
applicants, are limited to 6 pages. Follow all instructions for the Appendix as described in the SF424
(R&R) Application Guide. Only the items listed in NOT-OD-17-098, plus additional items specifically listed
in this funding opportunity announcement, are allowed.
PHS Human Subjects and Clinical Trials Information (Communication, Outreach, and
Education Core)
When involving human subjects research, clinical research, and/or NIH-defined clinical trials follow all
instructions for the PHS Human Subjects and Clinical Trials Information form in the SF424 (R&R)
Application Guide, with the following additional instructions:
If you answered “Yes” to the question “Are Human Subjects Involved?” on the R&R Other Project
Information form, you must include at least one human subjects study record using the Study Record:
PHS Human Subjects and Clinical Trials Information form or a Delayed Onset Study record.
Study Record: PHS Human Subjects and Clinical Trials Information
All instructions in the SF424 (R&R) Application Guide must be followed
Delayed Onset Study
Note: Delayed onset does NOT apply to a study that can be described but will not start immediately (i.e.,
delayed start).All instructions in the SF424 (R&R) Application Guide must be followed.
Research-to-Practice Core (Required)
When preparing your application, use Component Type ‘Research to Practice.’
All instructions in the SF424 (R&R) Application Guide must be followed.
SF424 (R&R) Cover (Research-to-Practice Core)
Complete only the following fields:
· Applicant Information
· Type of Applicant (optional)
· Descriptive Title of Applicant’s Project
· Proposed Project Start/Ending Dates
PHS 398 Cover Page Supplement (Research-to-Practice Core)
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Research & Related Other Project Information (Research-to-Practice Core)
Human Subjects: Answer only the ‘Are Human Subjects Involved?’ and 'Is the Project Exempt from
Federal regulations?’ questions.
Vertebrate Animals: Answer only the ‘Are Vertebrate Animals Used?’ question.
Project Narrative: In 1-3 sentences, describe the relevance of the research-to-practice efforts proposed
in the Core.
Project /Performance Site Location(s) (Research-to-Practice Core)
List all performance sites that apply to the specific component.
Note: The Project Performance Site form allows up to 300 sites, prior to using additional attachment for
additional entries.
Research & Related Senior/Key Person Profile (Research-to-Practice Core)
In the Project Director/Principal Investigator section of the form, use Project Role of ‘Other’ with Category
of ‘Core Lead’ and provide a valid eRA Commons ID in the Credential field. In the additional Senior/Key
Profiles section, list Senior/Key persons that are working in the component.
Include a single Biographical Sketch for each Senior/Key person listed in the application regardless of the
number of components in which they participate. When a Senior/Key person is listed in multiple
components, the Biographical Sketch can be included in any one component.
The Core lead should have the expertise appropriate to manage all aspects of the Core successfully.
Budget (Research-to-Practice Core)
Budget forms appropriate for the specific component will be included in the application package.
For this NOFO, CDC/NIOSH requires a detailed budget for the initial budget year and a budget for each
consecutive year of support.
Approximate budget allocation guidance has been provided in Section I.2. Approach. Applicants may
request with justification more or less funding for any of the Cores provided they do not exceed the total
costs allowed under this NOFO and that all required Cores are included in the application.
The Pilot Study Program is an optional element for the Research-to-Practice Core and is intended to
assist the Center in addressing new or emerging issues that were not present or recognizable at the time
of application.
Note: The R&R Budget form included in many of the component types allows for up to 100 Senior/Key
Persons in section A and 100 Equipment Items in section C prior to using attachments for additional
entries. All other SF424 (R&R) instructions apply.
PHS 398 Research Plan (Research-to-Practice Core)
Introduction to Application: For Resubmission and Revision applications, an Introduction to Application
is allowed for each component.
Specific Aims: Describe the broad, long-range, and short-term objectives and goals of the Research-to-
Practice Core, highlighting its role in facilitating the adoption of interventions and technologies to reduce
occupational injuries, illness, and fatalities in the construction sector.
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Research Strategy:
Describe how the proposed activities of the Research-to-Practice Core will directly contribute to the
achievement of the Center's overall goals and objectives. Highlight the key areas where the Core's efforts
will have the most impact on reducing occupational injuries, illness, and fatalities in the construction
industry.
Provide a rationale for the selection of proposed activities and approaches to accomplish its specific aims.
Explain why these choices are the most effective and suitable for bridging the gap between research and
practice in the construction sector.
The Research-to-Practice Core should include the development and transfer of new technologies and/or
tests the efficacy of information dissemination strategies (e.g., that contributes much-needed information
to the scientific knowledge base).
Letters of Support: Provide any letters of support that are specific to this core.
Resource Sharing Plan:
Individuals are required to comply with the instructions for the Resource Sharing Plans as provided in the
SF424 (R&R) Application Guide with the following modifications.
Applicants that plan to collect public health data must submit a Data Management Plan (DMP) in the
Resource Sharing Plan section of the PHS 398 Research Plan Component of the application. A DMP is
required for each collection of public health data proposed. Applicants who contend that the public health
data they collect or create are not appropriate for release must justify that contention in the DMP
submitted with their application for CDC funds.
The DMP may be outlined in a narrative format or as a checklist but, at a minimum, should include:
• A description of the data to be collected or generated in the proposed project;
• Standards to be used for the collected or generated data;
• Mechanisms for, or limitations to, providing access to and sharing of the data (include a description of
provisions for the protection of privacy, confidentiality, security, intellectual property, or other rights - this
section should address access to identifiable and de-identified data);
• Statement of the use of data standards that ensure all released data have appropriate documentation
that describes the method of collection, what the data represent, and potential limitations for use; and
• Plans for archiving and long-term preservation of the data, or explaining why long-term preservation and
access are not justified (this section should address archiving and preservation of identifiable and de-
identified data).
CDC OMB-approved templates may be used (e.g., NCCDPHP template).
Appendix:
Past performance and/or prior accomplishments within the last 5 years, whether for new or renewal
applicants, are limited to 6 pages. Follow all instructions for the Appendix as described in the SF424
(R&R) Application Guide. Only the items listed in NOT-OD-17-098, plus additional items specifically listed
in this funding opportunity announcement, are allowed.
PHS Human Subjects and Clinical Trials Information (Research-to-Practice Core)
When involving human subjects research, clinical research, and/or NIH-defined clinical trials follow all
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
instructions for the PHS Human Subjects and Clinical Trials Information form in the SF424 (R&R)
Application Guide, with the following additional instructions:
If you answered “Yes” to the question “Are Human Subjects Involved?” on the R&R Other Project
Information form, you must include at least one human subjects study record using the Study Record:
PHS Human Subjects and Clinical Trials Information form or a Delayed Onset Study record.
Study Record: PHS Human Subjects and Clinical Trials Information
All instructions in the SF424 (R&R) Application Guide must be followed
Delayed Onset Study
Note: Delayed onset does NOT apply to a study that can be described but will not start immediately (i.e.,
delayed start).All instructions in the SF424 (R&R) Application Guide must be followed
Research Projects (Required)
When preparing your application, use Component Type ‘Project.’ Applicants will complete
this form set for each individual research project.
All instructions in the SF424 (R&R) Application Guide must be followed.
SF424 (R&R) Cover (Research Project)
Complete only the following fields:
· Applicant Information
· Type of Applicant (optional)
· Descriptive Title of Applicant’s Project
· Proposed Project Start/Ending Dates
PHS 398 Cover Page Supplement (Research Project)
Research & Related Other Project Information (Research Project)
Human Subjects: Answer only the ‘Are Human Subjects Involved?’ and 'Is the Project Exempt from
Federal regulations?’ questions.
Vertebrate Animals: Answer only the ‘Are Vertebrate Animals Used?’ question.
Project Narrative: In 1-3 sentences, describe the relevance of the proposed research.
Project /Performance Site Location(s) (Research Project)
List all performance sites that apply to the specific component.
Note: The Project Performance Site form allows up to 300 sites, prior to using additional attachment for
additional entries.
Research & Related Senior/Key Person Profile (Research Project)
In the Project Director/Principal Investigator section of the form, use Project Role of ‘Other’ with Category
of ‘Project Lead’ and provide a valid eRA Commons ID in the Credential field. In the additional Senior/Key
Profiles section, list Senior/Key persons that are working in the component.
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Include a single Biographical Sketch for each Senior/Key person listed in the application regardless of the
number of components in which they participate. When a Senior/Key person is listed in multiple
components, the Biographical Sketch can be included in any one component.
The Research Project lead should have the expertise appropriate to manage all aspects of the Project
successfully.
Budget (Research Project)
Budget forms appropriate for the specific component will be included in the application package.
There are no established funding limits for individual research projects. Applicants must work within the
overall funding level for the Applied Research Core. The Applied Research Core is comprised of all
research projects. Research projects can span any number of years within the Center's five-year project
period. That is, research projects can be from 1 to 5 years in length.
For this NOFO, CDC/NIOSH requires a detailed budget for the initial budget year and a budget for each
consecutive year of support.
Note: The R&R Budget form included in many of the component types allows for up to 100 Senior/Key
Persons in section A and 100 Equipment Items in section C prior to using attachments for additional
entries. All other SF424 (R&R) instructions apply.
PHS 398 Research Plan (Research Project)
Introduction to Application: For Resubmission and Revision applications, an Introduction to Application
is allowed for each project.
Specific Aims: Briefly describe the overall specific aims of the research project. Clearly describe the
relationship of the research project to the overall Center's goals.
Research Strategy: It is anticipated that proposed research projects will vary widely in terms of
topic/focus, degree of difficulty, and required resources. The projects should clearly align with the overall
goals of the NIOSH Construction Program. The research strategy should be limited to 12 pages.
The need for individual research projects should be supported by information that addresses burden,
need, and impact for occupational safety and health in the construction sector. Applied research may
include emerging technologies, approaches, and techniques. Applied research builds the evidence base
for effective prevention and intervention practices that ultimately result in lower burden.
Individual research project proposals may vary in scope, duration, and cost with the number of years of
support (not to exceed 5 years), and budget. Each project must be written as a stand-alone section using
the guidance provided in this announcement (see Section IV., No. 2) to facilitate peer review of individual
projects.
NIOSH encourages hypothesis-driven research proposals that address priority topics (as determined by
burden, need, and impact), involve comparison population(s), and a strong, descriptive data analysis
plan. For projects involving multiple institutions, the proposal should contain descriptive letters of
collaboration that substantiate key roles and responsibilities and address any overlap or duplication.
Letters of Support: Provide any letters of support that are specific to the research project, particularly for
letters of collaboration or from consultants.
Resource Sharing Plan:
Individuals are required to comply with the instructions for the Resource Sharing Plans as provided in the
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
SF424 (R&R) Application Guide with the following modifications.
Applicants that plan to collect public health data must submit a Data Management Plan (DMP) in the
Resource Sharing Plan section of the PHS 398 Research Plan Component of the application. A DMP is
required for each collection of public health data proposed. Applicants who contend that the public health
data they collect or create are not appropriate for release must justify that contention in the DMP
submitted with their application for CDC funds.
The DMP may be outlined in a narrative format or as a checklist but, at a minimum, should include:
• A description of the data to be collected or generated in the proposed project;
• Standards to be used for the collected or generated data;
• Mechanisms for, or limitations to, providing access to and sharing of the data (include a description of
provisions for the protection of privacy, confidentiality, security, intellectual property, or other rights - this
section should address access to identifiable and de-identified data);
• Statement of the use of data standards that ensure all released data have appropriate documentation
that describes the method of collection, what the data represent, and potential limitations for use; and
• Plans for archiving and long-term preservation of the data, or explaining why long-term preservation and
access are not justified (this section should address archiving and preservation of identifiable and de-
identified data).
CDC OMB-approved templates may be used (e.g., NCCDPHP template).
Appendix:
Past performance and/or prior accomplishments within the last 5 years, whether for new or renewal
applicants, are limited to 6 pages. Follow all instructions for the Appendix as described in the SF424
(R&R) Application Guide. Only the items listed in NOT-OD-17-098, plus additional items specifically listed
in this funding opportunity announcement, are allowed.
PHS Human Subjects and Clinical Trials Information (Research Project)
When involving human subjects research, clinical research, and/or NIH-defined clinical trials follow all
instructions for the PHS Human Subjects and Clinical Trials Information form in the SF424 (R&R)
Application Guide, with the following additional instructions:
If you answered “Yes” to the question “Are Human Subjects Involved?” on the R&R Other Project
Information form, you must include at least one human subjects study record using the Study Record:
PHS Human Subjects and Clinical Trials Information form or a Delayed Onset Study record.
Study Record: PHS Human Subjects and Clinical Trials Information
All instructions in the SF424 (R&R) Application Guide must be followed
Delayed Onset Study
Note: Delayed onset does NOT apply to a study that can be described but will not start immediately (i.e.,
delayed start).All instructions in the SF424 (R&R) Application Guide must be followed.
3. Unique Entity Identifier and System for Award Management
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
(SAM)
See Part 2. Section III.1 for information regarding the requirement for obtaining a unique
entity identifier and for completing and maintaining active registrations in System for
Award Management (SAM), NATO Commercial and Government Entity (NCAGE) Code (if
applicable), eRA Commons, and Grants.gov.
4. Submission Dates and Times
Part I. Overview Information contains information about Key Dates. Applicants are strongly
encouraged to allocate additional time and submit in advance of the deadline to ensure
they have time to make any corrections that might be necessary for successful
submission. This includes the time necessary to complete the application resubmission
process that may be necessary, if errors are identified during validation by Grants.gov and
the NIH eRA systems. The application package is not complete until it has passed the
Grants.gov and NIH eRA Commons submission and validation processes. Applicants will
use a platform or system to submit applications. When a submission date falls on a
weekend or Federal holiday, the application deadline is automatically extended to the next
business day.
ASSIST is a commonly used platform because it provides a validation of all requirements
prior to submission. If ASSIST detects errors, then the applicant must correct errors before
their application can be submitted. Applicants should view their applications in ASSIST
after submission to ensure accurate and successful submission through Grants.gov. If the
submission is not successful and post-submission errors are found, then those errors
must be corrected, and the application must be resubmitted in ASSIST.
Applicants are able to access, view, and track the status of their applications in the eRA
Commons.
Information on the submission process is provided in the SF-424 (R&R) Application
Guidance and ASSIST User Guide.
Note: HHS/CDC grant submission procedures do not provide a grace period beyond the
grant application due date time to correct any error or warning notices of noncompliance
with application instructions that are identified by Grants.gov or eRA systems (i.e., error
correction window).
Applicants who encounter problems when submitting their applications must attempt to
resolve them by contacting the NIH eRA Service desk at:
Toll-free: 1-866-504-9552; Phone: 301-402-7469
http://grants.nih.gov/support/index.html
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
Hours: Mon-Fri, 7 a.m. to 8 p.m. Eastern Time (closed on Federal holidays)
Problems with Grants.gov can be resolved by contacting the Grants.gov Contact Center
at:
Toll-free: 1-800-518-4726
https://www.grants.gov/web/grants/support.html
support@grants.gov
Hours: 24 hours a day, 7 days a week; closed on Federal holidays
It is important that applicants complete the application submission process well in advance
of the due date time.
After submission of your application package, applicants will receive a "submission
receipt" email generated by Grants.gov. Grants.gov will then generate a second e-
mail message to applicants which will either validate or reject their submitted
application package. A third and final e-mail message is generated once the
applicant's application package has passed validation and the grantor agency has
confirmed receipt of the application.
Unsuccessful Submissions: If an application submission was unsuccessful, the
applicant must:
1. Track submission and verify the submission status (tracking should be done initially
regardless of rejection or success).
a. If the status states "rejected," be sure to save time stamped, documented rejection
notices, and do #2a or #2b.
2. Check emails from both Grants.gov and NIH eRA Commons for rejection notices. If the
status states "rejected" and there is time before the deadline, correct the problem(s) and
resubmit as soon as possible.
a. If the deadline has passed, he/she should email the Grants Management contact listed
in the Agency Contacts section of this announcement explaining why the submission
failed.
b. If there is time before the deadline, correct the problem(s) and resubmit as soon as
possible.
Electronically submitted applications must be submitted no later than 11:59 PM Eastern
Time on the listed application due date.
Applicants are responsible for viewing their application before the due date in the
eRA Commons to ensure accurate and successful submission.
Information on the submission process and a definition of on-time submission are
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
provided in the SF424 (R&R) Application Guide.
5. Intergovernmental Review (E.O. 12372)
This initiative is not subject to intergovernmental review.
6. Funding Restrictions
Expanded Authority:
For more information on expanded authority and pre-award costs, go to the HHS Grants
Policy Statement and speak to your GMS.
All HHS/CDC awards are subject to the federal regulations, in 45 CFR Part 75, terms and
conditions, and other requirements described in the HHS Grants Policy Statement. pre-
award costs may be allowable as an expanded authority, but only if authorized by CDC.
Public Health Data:
CDC requires that mechanisms for, and cost of, public health data sharing be included in
grants, cooperative agreements, and contracts. The cost of sharing or archiving public
health data may also be included as part of the total budget requested for first-time or
continuation awards.
Data Management Plan:
Fulfilling the data-sharing requirement must be documented in a Data Management Plan (DMP) that is
developed during the project planning phase prior to the initiation of generating or collecting public health
data and must be included in the Resource Sharing Plan(s) section of the PHS398 Research Plan
Component of the application.
Applicants who contend that the public health data they collect or create are not appropriate for release
must justify that contention in the DMP submitted with their application for CDC funds (for example,
privacy and confidentiality considerations, embargo issues).
Recipients who fail to release public health data in a timely fashion will be subject to
procedures normally used to address lack of compliance (for example, reduction in
funding, restriction of funds, or award termination). For further information, please see
revised AR25.
Human Subjects:
Funds relating to the conduct of research involving human subjects will be restricted until
the appropriate assurances and Institutional Review Board (IRB) approvals are in place.
Copies of all current local IRB approval letters and local IRB approved protocols (and
CDC IRB approval letters, if applicable) will be required to lift restrictions.
If the proposed research project involves more than one institution and will be conducted
in the United States, awardees are expected to use a single Institutional Review Board
(sIRB) to conduct the ethical review required by HHS regulations for the Protections of
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
Human Subjects Research, and include a single IRB plan in the application, unless review
by a sIRB would be prohibited by a federal, tribal, or state law, regulation, or policy or a
compelling justification based on ethical or human subjects protection issues or other well-
justified reasons is provided. Exceptions will be reviewed and approved by CDC in
accordance with Department of Health and Human Services (DHHS) Regulations (45 CFR
Part 46), or a restriction may be placed on the award. For more information, please
contact the scientific/research contact included on this NOFO.
Note: The sIRB requirement applies to participating sites in the United States.
Foreign sites participating in CDC-funded, cooperative research studies are not
expected to follow the requirement for sIRB.
Awards may be initially issued with restrictions until all information requested can be
provided. Generally, funds will not be given for renovation of existing facilities or for
purchasing substantial amounts of equipment.
7. Other Submission Requirements and Information
Applications must be submitted electronically following the instructions described in the
SF424 (R&R) Application Guide. Paper applications will not be accepted.
For information on how your application will be automatically assembled for review and
funding consideration after submission go to:
http://grants.nih.gov/grants/ElectronicReceipt/files/Electronic_Multi-
project_Application_Image_Assembly.pdf.
Applicants must complete all required registrations before the application due date.
Section III. Eligibility Information contains information about registration.
For assistance with your electronic application or for more information on the electronic
submission process, visit How to Apply – Application Guide. If you encounter a system
issue beyond your control that threatens your ability to complete the submission process
on-time, you must follow the Dealing with System Issues guidance. For assistance with
application submission, contact the Application Submission Contacts in Section VII.
Important reminders:
All PD(s)/PI(s) and component Project Leads must include their eRA Commons ID in the
Credential field of the Senior/Key Person Profile form. Failure to register in the Commons
and to include a valid PD/PI Commons ID in the credential field will prevent the successful
submission of an electronic application to NIH.
The applicant organization must ensure that the unique entity identifier provided on the
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RFA-OH-24-001: National Center for Construction Safety and Health Research and Translation (U54)
application is the same identifier used in the organization’s profile in the eRA Commons
and for the System for Award Management. Additional information may be found in the
SF424 (R&R) Application Guide.
See more tips for avoiding common errors.
Upon receipt, applications will be evaluated for completeness by the CDC Office of Grants
Services (OGS) and responsiveness by OGS and the Center, Institute or Office of the
CDC. Applications that are incomplete and/or nonresponsive will not be reviewed.
Risk Assessment Questionnaire Requirement
CDC is required to conduct pre-award risk assessments to determine the risk an applicant
poses to meeting federal programmatic and administrative requirements by taking into
account issues such as financial instability, insufficient management systems, non-
compliance with award conditions, the charging of unallowable costs, and inexperience.
The risk assessment will include an evaluation of the applicant’s CDC Risk Questionnaire,
as well as a review of the applicant’s history in all available systems; including OMB-
designated repositories of government-wide eligibility and financial integrity systems (see
45 CFR 75.205(a)), and other sources of historical information. These systems include,
but are not limited to: FAPIIS, including past performance on federal contracts as per
Duncan Hunter National Defense Authorization Act of 2009; Do Not Pay list; and System
for Award Management (SAM) exclusions.
CDC requires all applicants to complete the Risk Questionnaire, OMB Control Number
0920-1132 annually. This questionnaire, along with supporting documentation must be
submitted with your application by the closing date of the Notice of Funding Opportunity
Announcement. If your organization has completed CDC’s Risk Questionnaire within the
past 12 months of the closing date of this NOFO, then you must submit a copy of that
questionnaire, or submit a letter signed by the authorized organization representative to
include the original submission date, organization’s EIN and UEI.
When uploading supporting documentation for the Risk Questionnaire into this application
package, clearly label the documents for easy identification of the type of documentation.
For example, a copy of Procurement policy submitted in response to the questionnaire
may be labeled using the following format: Risk Questionnaire Supporting Documents _
Procurement Policy. Upload the questionnaire and supporting documents as an
attachment in the "12. Other Attachments" section of the "R&R Other Project
Information" section of the application.
Duplication of Efforts
Applicants are responsible for reporting if this application will result in programmatic,
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