Fundamental Research to Counter Weapons of Mass Destruction

Fundamental Research BAA Amendment 2 posted on January 15, 2026 This Amendment adds Topics B1-B6. PRE-APPLICATION WHITE PAPERS FOR THIS TOPIC MUST BE SUBMITTED BY 11:59 PM (MIDNIGHT) EST ON 2 MARCH 2026. White papers may not be considered if they are received after this deadline. Potential applicants are strongly encouraged to review the BAA in its entirety. **Please note that ALL general correspondence for this BAA must be sent to dtra.belvoir.rd.mbx.rd-cb-frbaa25-34-a@mail.mil Thrust Area-specific correspondence must be sent to dtra.belvoir.rd.mbx.rd-cb-frbaa25-34-a@mail.mil

Details

• Agency: Defense Threat Reduction Agency
• Department: Department of Defense
• Opportunity #: HDTRA1-25-S-0001
• Total Funding: $500,000,000
• Expected Awards: 10
• Instrument: cooperative_agreement;grant

Eligibility

See Section 3. “Eligibility Information”, of the BAA for full Eligibility Requirements.

Amendment 2 Topics B1-B6

DEFENSE THREAT REDUCTION AGENCY
BROAD AGENCY ANNOUNCEMENT
HDTRA1-25-S-0001
Amendment 3
Posted January 22, 2026
Research and Development Directorate (RD)
Chemical and Biological Technologies Department (RD-CB)
Fundamental Research to Counter Weapons
of Mass Destruction (C-WMD)
Original Posting Date: 1 October 2024
H DTRA1-25-S-0001 Page 1

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TABLE OF CONTENTS
SECTION NO. PAGE NO.
OVERVIEW INFORMATION .................................................................................................3

1. FUNDING OPPORTUNITY DESCRIPTION .......................................................................5
2. AWARD INFORMATION .....................................................................................................6
3. ELIGIBILITY INFORMATION ............................................................................................8
4. APPLICATION AND SUBMISSION INFORMATION .....................................................10
5. APPLICATION REVIEW INFORMATION .......................................................................23
6. AWARD ADMINISTRATION INFORMATION ...............................................................26
7. AGENCY CONTACTS ........................................................................................................36
8. OTHER INFORMATION .....................................................................................................36

ATTACHMENT 1: SPECIFIC TOPICS ...................................................................................37
ATTACHMENT 2: INTELLECTUAL PROPERTY ............................................................... 59
H DTRA1-25-S-0001 Page 2

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OVERVIEW INFORMATION
Agency Name:
Defense Threat Reduction Agency (DTRA)
Research and Development (RD) Directorate
Chemical and Biological Technologies Department (CB)
8725 John J. Kingman Road, MS 6201
Fort Belvoir, VA 22060-6201
Funding Opportunity Title: Fundamental Research to Counter Weapons of Mass Destruction
(FRCWMD) Broad Agency Announcement (BAA)
Announcement Type: This is the initial announcement of this funding opportunity. This BAA
is in effect from October 1, 2024 through September 30, 2034. It is anticipated that a majority of
the actions funded from this announcement will be in the form of grants; however, other
instruments such as cooperative agreements (CAs) or other transactions (OTs) for research may
also be awarded from this announcement. No contracts will be awarded from this
announcement.