Dravet Syndrome Foundation Inc logo

Dravet Syndrome Foundation Inc

CHERRY HILL, NJ EIN: 27-0924627 Website

The mission of the Dravet Syndrome Foundation is to aggressively raise funds for Dravet syndrome & related epilepsies; support & fund research; increase awareness; & provide support to affected individuals & families. We understand the ongoing need to fund innovative research, the urgency in finding better treatments, the motivation of our donors to make an impact specifically in the fields of Dravet syndrome and related epilepsies, the importance of transparency and accountability of not only our organization, but the researchers that we fund, and the need for global collaboration in order to find a cure.

Financial Overview

From 2024 IRS Form 990-PF · View filing

Total Assets

$8.5M

+13.7% YoY

Annual Giving

$2.0M

+157.7% YoY

Grant Count

7

+40.0% YoY

Avg Grant Size

$284K

+84.1% YoY

About Dravet Syndrome Foundation Inc

Based on IRS filings

Dravet Syndrome Foundation Inc is a nonprofit organization focused on Philanthropy, Voluntarism & Grantmaking, based in CHERRY HILL, NJ. IRS filing data is available from 2020 through 2024. As of 2024, the organization holds $8.5M in total assets. In 2024, it awarded 7 grants totaling $2.0M. Net investment income was $304K.

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Geographic Focus

Where this funder awards grants

Grant Distribution by State

14states
+6 more states

Cities

AlbanyAnn ArborAuroraAustinCamdenClevelandColumbusEustisEvanstonMinneapolisNashvillePhiladelphiaProvidenceSalt Lake CitySt Louis

Financial History

Multi-year comparison from IRS filings

Revenue
Expenses
Qualifying Distributions
Net Investment Income
$0$1M$2M$4M$5M20202021202220232024
Metric202420232022
Total Assets$8,536,916$7,509,902$6,249,148
Revenue$4,221,622$3,257,096$2,515,782
Expenses$4,259,172$2,163,052$2,028,839
Qualifying Distributions
Net Investment Income$304,376$218,414$88,364
Distributable Amount

Giving Over Time

Total grant dollars and number of grants per year

$0$497K$994K$1M$2M2 grants20204 grants20214 grants20225 grants20237 grants2024

Grant Insights

How this funder distributes its grants

Top Recipients

Top 7 recipients in 2024

Children's Hospital of P…$1.0MRegents Of The Universit…$500KBrown University$250KChildren's Hospital of P…$75KUniversity of Colorado D…$75KRegents Of The Universit…$75KCoriell Institute for Me…$13K

Grant Size Distribution

22 grants across all recorded years

4<$50K6$50–100K9$100–250K1$250–500K1$500K–1M1$1–5M$5M+

Open Grants

7 open opportunities from Dravet Syndrome Foundation Inc

Show all 7 →

Giving History

Grant recipients and amounts by year

Among its reported 2024 grants, the largest include Children's Hospital of Philadelphia ($1,000,000), Regents Of The University Of Michigan ($500,000), Brown University ($250,000).

RecipientPurposeAmount
Children's Hospital of Philadelphia Philadelphia, PAIndividuals with Dravet syndrome (DS) can have different disease courses, and there are important differences in how seizure and development affect them over time. Identifying the causes of variation within the patient population may be helpful in providing accurate prognosis and developing new treatments. This project will generate broad genetic data with whole genome sequencing on 500 individuals with DS. These genetic analyses will be paired with clinical data using pioneered novel methods to transform clinical information to a format that can be used for computational analysis. Finally, this project is built for data sharing - all biosample data, genomic data, and clinical data will be shared within the DS Community.$1,000,000
Regents Of The University Of Michigan Ann Arbor, MIDespite recent advances in small molecule drug discovery, the majority of Dravet syndrome (DS) patients remain intractable and non-seizure symptoms are not addressed. This project aims to exploit an alternative therapeutic strategy that has been successful in mouse models: Medial Ganglionic Eminence (MGE) progenitor cell transplantation to restore healthy fast-spiking interneurons in DS patient brains. While transgenic mice have provided invaluable insights into seizures and some comorbidities associated with DS, mice have critical differences in physiology and neuroanatomy compared to humans and thus are not the most appropriate model to test a cell transplantation-based therapy. In contrast, this study will use rabbits, which are larger vertebrates, more similar to humans. The results of this large animal work will strengthen the preclinical foundation for future cell transplantation therapeutic strategies in DS patients.$500,000
Brown University Providence, RIThe scientific understanding of how the SCN1A gene changes brain activity is rapidly evolving. This work will explore whether a brain cell that is integrally important in Dravet syndrome symptomatology has disruptions that lead to specific malfunctions. This work aims to determine how mutations in the SCN1A gene impact these cells' normally powerful ability to "put the brakes on" the brain when it is too active. We believe that the loss of this "brake" may lead to seizures, and our experiments may yield important clues about how to get it working again.$250,000
Children's Hospital of Philadelphia Philadelphia, PAMutations in the SCN1A gene most commonly cause reduced functioning of the Nav1.1 protein and lead to Dravet syndrome, a debilitating epilepsy disorder. However, a new class of SCN1A mutations causes excessive activity of Nav1.1. Individuals with these mutations exhibit an even more severe form of epilepsy as well as developmental delay and intellectual disability. This research group has generated the first mouse expressing a patient-derived mutation associated with this severe early-onset condition. In this fellowship, they will evaluate the novel mouse for neurological abnormalities, including seizures and movement disorders. Additionally, they will investigate the electrical properties of neurons. The overall goal is to understand the mechanism by which both reduced and excessive activity of Nav1.1 can cause epilepsy and to identify treatments for both disorders.$75,000
University of Colorado Denver Aurora, COCurrent precision therapeutic clinical trials for Dravet syndrome (DS) utilize seizure frequency as the primary outcome measure, but using this alone to assess outcome does not capture the full array of challenges associated with DS. This project will focus on refining a set of clinician and caregiver-reported outcome measures previously created for CDKL5-deficiency disorder and piloting them in patients with DS. The overarching objective is to design valid and feasible outcome measures specifically for DS that represent the full range of the phenotype. The creation of the DS clinical severity assessment-clinician and caregiver (DS-CSA) will be a crucial step towards disease modifying clinical trial readiness in DS.$75,000
Regents Of The University Of Michigan Ann Arbor, MIIndividuals with Dravet syndrome (DS) suffer from severe seizures that cannot be completely controlled by medications. While most epilepsy research has focused on the more superficial brain regions that we know are prone to seizures, an improved understanding of the role of deeper brain regions in epilepsy may open the door to new therapies. The focus of this proposal is a deep brain region called the locus coeruleus, which sends noradrenergic projections throughout seizure-prone brain regions. The locus coeruleus is known as a "master regulator" that coordinates brain-wide states, such as reward and attention; this project will test the hypothesis that it also plays a critical role in seizures in DS using a mouse model of DS, to (1) determine the activity of noradrenergic neurons during seizures and (2) test whether their activation curtails seizures.$75,000
Coriell Institute for Medical Research Camden, NJThis project aims to establish a biobank of five unique lines of commercially-available induced pluripotent stem cells (iPSCs) from patient blood samples. The cellular reprogramming will be conducted by the Coriell Institute for Medical Research and samples will be housed and distributed through an additional partnership with the Orphan Disease Center at The University of Pennsylvania. Cell lines will be available to researchers in academic and for-profit research settings at a low cost, set to cover the long-term maintenance of the biobank effort.$12,617

Leadership & Key People

Officers and directors from IRS filings

Compensation Overview

From 2024 IRS filing

Mary Anne MeskisExecutive Director$173KVeronica HoodScientific Director$165KJamie CohenFinance & Program Director$109K

From 2024 filing

NameTitleHoursCompensation
Mary Anne MeskisExecutive Director40$172,586
Veronica HoodScientific Director40$165,459
Jamie CohenFinance & Program Director40$108,866
Ted Odlaug PhDPresident1
Ross NicholasVice President1
Claire CareySecretary1
Josh GoldmanTreasurer1
Nathan BattTrustee1
Ashley KernsTrustee1
Joseph Sullivan MDTrustee1
Bill KirshnerTrustee1
Gail FarfelTrustee1
Amanda PratherTrustee1

Subject Areas

Focus areas based on grantmaking activity

Frequently Asked Questions

What is Dravet Syndrome Foundation Inc?

Dravet Syndrome Foundation Inc is a nonprofit organization focused on Philanthropy, Voluntarism & Grantmaking, based in CHERRY HILL, NJ. It holds $8.5M in total assets as of 2024.

How large is Dravet Syndrome Foundation Inc?

As of 2024, Dravet Syndrome Foundation Inc holds $8.5M in total assets with $4.2M in annual revenue. It awarded 7 grants totaling $2.0M in 2024.

Where does Dravet Syndrome Foundation Inc operate?

Dravet Syndrome Foundation Inc has awarded grants in Colorado, Florida, Illinois, Michigan, Minnesota, Missouri, New Jersey, New York, Ohio, Pennsylvania, Rhode Island, Tennessee, Texas, Utah.

What size grants does Dravet Syndrome Foundation Inc award?

In 2024, Dravet Syndrome Foundation Inc awarded 7 grants totaling $2.0M — an average of about $284K per grant, based on its IRS Form 990 filings.

What is Dravet Syndrome Foundation Inc's EIN?

Dravet Syndrome Foundation Inc's EIN (Employer Identification Number) is 27-0924627. IRS Form 990 filing data is available on this page for 2020–2024.

Explore Open Grants

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Data last updated April 2026. Sourced from IRS Form 990-PF filings.

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