Robert J & Helen C Kleberg Foundation logo

Robert J & Helen C Kleberg Foundation

SAN ANTONIO, TX EIN: 74-6044810 Website

The Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation is a private grantmaking foundation incorporated in 1950 and headquartered in San Antonio, Texas. The foundation was established by Robert J. Kleberg, Jr. and Helen C. Kleberg, who spent their lives working on King Ranch in South Texas. The foundation operates on a national basis with a particular focus on South Texas communities.

Financial Overview

From 2024 IRS Form 990-PF · View filing

Total Assets

$242.6M

+6.1% YoY

Annual Giving

$13.1M

-7.9% YoY

Grant Count

47

+2.2% YoY

Avg Grant Size

$279K

-9.8% YoY

Research compiled by Grantable AI from public sources. Last updated April 2026.

Mission & Focus Areas

The foundation's mission is to improve the world through the advancement of knowledge in medical and basic science research, conservation, community services, and the arts.

Primary funding areas include:

  • Medical research
  • Basic science research
  • Veterinary and animal sciences
  • Wildlife research and preservation
  • Health services
  • Higher education
  • Arts and humanities
  • Community services and local community organizations

Grantmaking

The foundation's ongoing relationships with universities and medical schools have contributed to significant accomplishments including the first successful bone marrow transplant from an unrelated donor, the Human Genome Project, transgenesis, and personalized medicine.

Grant Range

approximately $1,000 to $150,000

Average Grant

approximately $1,000 to $150,000

How to Apply

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Geographic Focus

Where this funder awards grants

The foundation funds on a national basis with particular emphasis on:

  • South Texas communities and Kleberg County
  • Adjacent South Texas regions
  • Major urban centers including New York, San Francisco, and Seattle
  • Numerous locations throughout Texas including Austin, Houston, and San Antonio

Grant Distribution by State

9states
+1 more states

Cities

AliceAustinBaltimoreBostonBrownsvilleCollege StationCorpus ChristiDallasEdingburgGalvestonHarlengenHarlingenHoustonKennett SquareKingsvilleMcallenMissionMount VernonNashvilleNew York

Financial History

Multi-year comparison from IRS filings

As of 2023:

  • Total Assets: $228.6 million to $229 million
  • Annual Revenue: $23 million
  • Annual Expenses: $17.1 million
  • Total Liabilities: $3.16 million

Tax Status:

  • 501(c)(3) organization
  • Tax-exempt since May 1952
  • EIN: 74-6044810
  • Donations are tax-deductible
Revenue
Expenses
Qualifying Distributions
Net Investment Income
$0$9M$18M$27M$36M20202021202220232024
Metric202420232022
Total Assets$242,609,804$228,649,086$221,326,840
Revenue$29,045,761$23,035,418$9,790,777
Expenses$15,135,374$17,137,275$17,505,259
Qualifying Distributions$13,260,091$14,383,604$14,857,285
Net Investment Income$27,154,612$20,863,598$7,463,289
Distributable Amount$14,381,273$13,380,468$14,156,928

Giving Over Time

Total grant dollars and number of grants per year

$0$4M$7M$11M$15M40 grants202041 grants202143 grants202246 grants202347 grants2024

Grant Insights

How this funder distributes its grants

Top Recipients

Top 10 recipients in 2024

BAYLOR COLLEGE OF MEDICINE$1.2MUNIVERSITY OF CALIFORNIA$1.0MUNIVERSITY OF TEXAS SOUT…$1.0MRICE UNIVERSITY$994KTHOMAS JEFFERSON UNIVERS…$839KUNIVERSITY OF TEXAS MD A…$657KUNIVERSITY OF TEXAS AUSTIN$625KFOUNDATION OF THE MASSAC…$600KVANDERBILT UNIVERSITY ME…$583KSTANFORD UNIVERSITY BOAR…$500K

Grant Size Distribution

217 grants across all recorded years

66<$50K25$50–100K30$100–250K44$250–500K35$500K–1M17$1–5M$5M+

Open Grants

4 open opportunities from Robert J & Helen C Kleberg Foundation

Show all 4 →

Giving History

Grant recipients and amounts by year

No grants recorded for .

Leadership & Key People

Leadership team and compensation from IRS filings

  • Helen C. Alexander: President
  • John D. Alexander Jr.: Principal Officer
  • John Alexander: Officer

The foundation's leadership includes a volunteer board, with all members serving without compensation.

Compensation Overview

From 2024 IRS filing

From 2024 filing

NameTitleHoursCompensation
HELEN C ALEXANDERPRESIDENT1
EMORY A HAMILTONV/P - TREASURER1
JOHN D ALEXANDER JRV/P - SECRETARY1
CAROLINE A FORGASONDIRECTOR1
HENRIETTA K ALEXANDERDIRECTOR1
DOROTHY A MATZVICE-PRESIDENT1
Helen A HamiltonDirector1
John D Alexander IIIDirector1

Recent News & Activity

Recent developments and announcements

The foundation has funded recent research initiatives including:

Foundation funds research to block drug resistance in cancer treatment -

Thomas Jefferson University research on bone destruction in metastatic breast cancer

Thomas Jefferson University Receives $1.25M Grant to Tackle Bone Destruction

Research to block drug resistance in cancer treatment

Foundation funds research to block drug resistance in cancer treatment -

Vanderbilt-Ingram Cancer Center cancer drug discovery project

Foundation funds research to block drug resistance in cancer treatment -

Monell Center research on bacterial and viral immune responses to reduce antibiotic use

Monell Center Receives Kleberg Foundation Grant to Discriminate Bacterial

Monell Center research on distinctive odor characteristics of ovarian cancer

Foundation funds research to block drug resistance in cancer treatment -

Data last updated April 2026. Sourced from IRS Form 990-PF filings. Research dossier generated April 2026.

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